Pharmacologic Characterization of AMG 334, a Potent and Selective Human Monoclonal Antibody against the Calcitonin Gene-Related Peptide Receptor

The Journal of pharmacology and experimental therapeutics

Volumn 356, Issue 1, 2016, Pages 223-231

  Shi, Licheng ^a   Lehto, Sonya G ^a   Zhu, Dawn X D ^a   Sun, Hong ^a   Zhang, Jianhua ^a   Smith, Brian P ^a   Immke, David C ^a   Wild, Kenneth D ^a   Xu, Cen ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN RECEPTOR; CAPSAICIN; CYCLIC AMP; ERENUMAB; MONOCLONAL ANTIBODY;

ANIMAL; ANTAGONISTS AND INHIBITORS; BINDING COMPETITION; BIOSYNTHESIS; BLOOD FLOW; DOG; DOSE RESPONSE; DRUG EFFECTS; HUMAN; MACACA FASCICULARIS; METABOLISM; MIGRAINE DISORDERS; MOUSE; RABBIT; RAT; SKIN; VASCULARIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; CALCITONIN GENE-RELATED PEPTIDE; CAPSAICIN; CYCLIC AMP; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MACACA FASCICULARIS; MICE; MIGRAINE DISORDERS; RABBITS; RATS; RECEPTORS, CALCITONIN; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; REGIONAL BLOOD FLOW; SKIN;

EID: 84991204447     PISSN: None     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.115.227793     Document Type: Article

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