Monocyte-derived macrophages from Crohn's disease patients are impaired in the ability to control intracellular adherent-invasive Escherichia coli and exhibit disordered cytokine secretion profile

Journal of Crohn's & colitis

Volumn 9, Issue 5, 2015, Pages 410-420

  Vazeille, Emilie ^a   Buisson, Anthony ^a   Bringer, Marie Agnès ^a   Goutte, Marion ^a   Ouchchane, Lemlih ^a   Hugot, Jean Pierre ^a   de Vallée, Amélie ^a   Barnich, Nicolas ^a   Bommelaer, Gilles ^a   Darfeuille Michaud, Arlette ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

adherent invasive E. coli; Crohn s disease; cytokines; infliximab; Macrophages

Indexed keywords

ATG16L1 PROTEIN, HUMAN; CARRIER PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; INFLIXIMAB; INTERLEUKIN 6; INTERLEUKIN 8; NOD2 PROTEIN, HUMAN; NONSTEROID ANTIINFLAMMATORY AGENT; TUMOR NECROSIS FACTOR;

ADULT; BACTERIAL LOAD; BACTERIUM ADHERENCE; CELL CULTURE; COMPARATIVE STUDY; CROHN DISEASE; DRUG EFFECTS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; FEMALE; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MACROPHAGE; MALE; MICROBIOLOGY; MIDDLE AGED; SECRETION (PROCESS); SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BACTERIAL ADHESION; BACTERIAL LOAD; CARRIER PROTEINS; CELLS, CULTURED; COLITIS, ULCERATIVE; CROHN DISEASE; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; GENOTYPE; HUMANS; INFLIXIMAB; INTERLEUKIN-6; INTERLEUKIN-8; MACROPHAGES; MALE; MIDDLE AGED; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, SINGLE NUCLEOTIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84991199507     PISSN: None     EISSN: 18764479     Source Type: Journal    
DOI: 10.1093/ecco-jcc/jjv053     Document Type: Article

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