Durable Viral Suppression and Transmission Risk Potential among Persons with Diagnosed HIV Infection: United States, 2012-2013

Clinical Infectious Diseases

Volumn 63, Issue 7, 2016, Pages 976-983

  Crepaz, Nicole ^a   Tang, Tian ^b   Marks, Gary ^a   Mugavero, Michael J ^c   Espinoza, Lorena ^a   Hall, H Irene ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b ICF INTERNATIONAL   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

disparity; durable viral suppression; HIV transmission risk; HIV diagnosed persons; viral burden

Indexed keywords

ADOLESCENT; ADULT; AFRICAN AMERICAN; AGE; ARTICLE; COHORT ANALYSIS; DURABLE VIRAL SUPPRESSION; ETHNICITY; FEMALE; HISPANIC; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; MEN WHO HAVE SEX WITH MEN; MIDDLE AGED; PATIENT CARE; PRIORITY JOURNAL; SEX DIFFERENCE; UNITED STATES; VIRAL PHENOMENA AND FUNCTIONS; VIREMIA; VIRUS LOAD; VIRUS TRANSMISSION; HUMAN IMMUNODEFICIENCY VIRUS 1; RISK; SUSTAINED VIROLOGIC RESPONSE; TRANSMISSION; VIROLOGY; YOUNG ADULT;

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ADOLESCENT; ADULT; ANTI-HIV AGENTS; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; MIDDLE AGED; RISK; SUSTAINED VIROLOGIC RESPONSE; UNITED STATES; VIRAL LOAD; YOUNG ADULT;

EID: 84990898362     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciw418     Document Type: Article

References (23)

1. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. Available at: http://www.aidsinfo.nih.gov/ ContentFiles/AdultandAdolescentGL.pdf. Accessed 30 January 2016.
2. Centers for Disease Control and Prevention, Health Resources and Services Administration, National Institutes of Health, American Academy of HIV Medicine, Association of Nurses in AIDS Care, International Association of Providers in AIDS Care, the National of Minority AIDS Council, and Urban Coalition for HIV/AIDS Prevention Services. Recommendations for HIV prevention with adults and adolescents with HIV in the United States, 2014. Available at: http:// stacks.cdc.gov/view/cdc/26062. Accessed 30 January 2016.
3. Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011; 365:493-505.
4. Mugavero MJ, Napravnik S, Cole SR, et al. Viremia copy-years predicts mortality among treatment-naive HIV-infected patients initiating antiretroviral therapy. Clin Infect Dis 2011; 53:927-35.
5. Quinn TC, Wawer MJ, Sewankambo N, et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1.Rakai Project Study Group. N Engl J Med 2000; 342:921-9.
6. Zoufaly A, Stellbrink HJ, Heiden MA, et al. Cumulative HIV viremia during highly active antiretroviral therapy is a strong predictor of AIDS-related lymphoma. J Infect Dis 2009; 200:79-87.
7. National Office on AIDS Policy. National HIV/AIDS strategy for the United States: updated to 2020. Available at: https://www.aids.gov/federal-resources/ national-hiv-aids-strategy/nhas-update.pdf. Accessed 30 January 3016.
8. Doshi RK, Milberg J, Isenberg D, et al. High rates of retention and viral suppression in the US HIV safety net system: HIV care continuum in the Ryan White HIV/AIDS program, 2011. Clin Infect Dis 2015; 60:117-25.
9. Althoff KN, Buchacz K, Hall HI, et al. U.S. trends in antiretroviral therapy use, HIV RNA plasma viral loads, and CD4 T-lymphocyte counts among HIV-infected persons, 2000 to 2008. Ann Intern Med 2012; 157:325-35.
10. Dombrowski JC, Kitahata MM, Van Rompaey SE, et al. High level of antiretroviral use and viral suppression among persons in HIV care in the United States, 2010. J Acquir Immune Defic Syndr 2013; 63:299-306.
11. Centers for Disease Control and Prevention. Monitoring selected national HIV prevention and care objectives by using HIV surveillance data-United States and 6 U.S. dependent areas-2013. HIV Surveillance Supplemental Report, 2015. 20(No. 2). Available at: http://www.cdc.gov/hiv/library/reports/surveillance/. Accessed 30 January 2016.
12. Centers for Disease Control and Prevention. Vital signs: HIV diagnosis, care, and treatment among persons living with HIV-United States, 2011. MMWR Morb Mortal Wkly Rep 2014; 63:1-6.
13. Marks G, Patel U, Stirratt MJ, et al. Single viral load measures overestimate stable viral suppression among HIV patients in care: clinical and public health implications. Acquir Immune Defic Syndr 2016.
14. Terzian AS, Bodach SD, Wiewel EW, et al. Novel use of surveillance data to detect HIV-infected persons with sustained high viral load and durable virologic suppression in New York City. PLoS One 2012; 7:e29679.
15. Marks G, Gardner LI, Rose CE, et al. Time above 1500 copies: a viral load measure for assessing transmission risk of HIV-positive patients in care. AIDS 2015; 29:947-54.
16. Crepaz N, Tungol MLV, Higa DH, et al. A systematic review of behavioral interventions for people living with HIV in the United States, 1988-2012. AIDS 2014; 28:633-56.
17. Mizuno Y, Zhu J, CrepazN, et al. Receipt ofHIV/STD prevention counseling byHIVinfected adults receiving medical care in the United States. AIDS 2014; 28:407-15.
18. International Advisory Panel on HIV Care Continuum Optimization. IAPAC guidelines for optimizing the HIV care continuum for adults and adolescents. J Int Assoc Provid AIDS Care 2015; 14(suppl 1):S3-34.
19. Marrazzo JM, Del Rio C, Holtgrave DR, et al. HIV prevention in clinical care settings: 2014 recommendations of the International Antiviral Society-USA Panel. JAMA 2014; 312:390-409.
20. Crepaz N, Baack BN, Higa DH, Mullins MM. Effects of integrated interventions on transmission risk and care continuum outcomes in persons living with HIV: meta-analysis, 1996-2014. AIDS 2015; 29:2371-83.
21. Centers for Disease Control and Prevention. Social determinants of health among adults with diagnosed HIV in 11 states, the District of Columbia and Puerto Rico, 2013. HIV Surveillance Supplemental Report. 2015; 20:1-38. http://www.cdc.gov/ hiv/library/reports/surveillance/. PublishedNovember 2015. Accessed 30 January 2016.
22. Weiser J, Beer L, Frazier EL, et al. Service delivery and patient outcomes in Ryan White HIV/AIDS Program-funded and-nonfunded health care facilities in the United States. JAMA Intern Med 2015; 175:1650-9.
23. Data to Care. Available at: https://effectiveinterventions.cdc.gov/en/highimpact prevention/publichealthstrategies/DatatoCare.aspx. Accessed 30 January 2016.