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Volumn 31, Issue 1, 2017, Pages 34-39

Maintenance therapy with decitabine in younger adults with acute myeloid leukemia in first remission: A phase 2 Cancer and Leukemia Group B Study (CALGB 10503)

(18)  Blum, W a   Sanford, B L b   Klisovic, R a   Deangelo, D J c   Uy, G d   Powell, B L e   Stock, W f   Baer, M R g   Kolitz, J E h   Wang, E S i   Hoke, E b   Mrozek K a   Kohlschmidt, J a,b   Bloomfield, C D a   Geyer, S j   Marcucci, G k   Stone, R M c   Larson, R A f  


Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; BUSULFAN; CYTARABINE; DAUNORUBICIN; DECITABINE; ETOPOSIDE; AZACITIDINE;

EID: 84990212570     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2016.252     Document Type: Article
Times cited : (63)

References (37)
  • 1
    • 0021266372 scopus 로고
    • Prolonged survival in acute myelogenous leukaemia without maintenance chemotherapy
    • Champlin R, Jacobs A, Gale RP, Boccia R, Elashoff R, Foon K et al. Prolonged survival in acute myelogenous leukaemia without maintenance chemotherapy. Lancet 1984; 1: 894-896
    • (1984) Lancet , vol.1 , pp. 894-896
    • Champlin, R.1    Jacobs, A.2    Gale, R.P.3    Boccia, R.4    Elashoff, R.5    Foon, K.6
  • 2
    • 0027275352 scopus 로고
    • Long-term outcome of patients with acute myelogenous leukemia: The role of maintenance therapy, consolidation therapy and the predictive value of two in vitro assays
    • Raza A, Preisler HD, Browman GP, Larson RA, Rustum YM, Goldberg J et al. Long-term outcome of patients with acute myelogenous leukemia: the role of maintenance therapy, consolidation therapy and the predictive value of two in vitro assays. Leuk Lymphoma 1993; 10: 57-66
    • (1993) Leuk Lymphoma , vol.10 , pp. 57-66
    • Raza, A.1    Preisler, H.D.2    Browman, G.P.3    Larson, R.A.4    Rustum, Y.M.5    Goldberg, J.6
  • 3
    • 0021369050 scopus 로고
    • Acute myelogenous leukaemia: Maintenance chemotherapy after early consolidation treatment does not prolong survival
    • Sauter C, Berchtold W, Fopp M, Gratwohl A, Imbach P, Maurice P et al. Acute myelogenous leukaemia: maintenance chemotherapy after early consolidation treatment does not prolong survival. Lancet 1984; 1: 379-382
    • (1984) Lancet , vol.1 , pp. 379-382
    • Sauter, C.1    Berchtold, W.2    Fopp, M.3    Gratwohl, A.4    Imbach, P.5    Maurice, P.6
  • 4
    • 33745003472 scopus 로고    scopus 로고
    • Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia
    • Büchner T, Berdel WE, Schoch C, Haferlach T, Serve HL, Kienast J et al. Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia. J Clin Oncol 2006; 24: 2480-2489
    • (2006) J Clin Oncol , vol.24 , pp. 2480-2489
    • Büchner, T.1    Berdel, W.E.2    Schoch, C.3    Haferlach, T.4    Serve, H.L.5    Kienast, J.6
  • 5
    • 1542753653 scopus 로고    scopus 로고
    • 6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): A randomized trial of the German AML Cooperative Group
    • Büchner T, Hiddemann W, Berdel WE, Wörmann B, Schoch C, Fonatsch C et al. 6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group. J Clin Oncol 2003; 21: 4496-4504
    • (2003) J Clin Oncol , vol.21 , pp. 4496-4504
    • Büchner, T.1    Hiddemann, W.2    Berdel, W.E.3    Wörmann, B.4    Schoch, C.5    Fonatsch, C.6
  • 6
    • 0035799382 scopus 로고    scopus 로고
    • Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
    • Santini V, Kantarjian HM, Issa JP. Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Ann Intern Med 2001; 134: 573-586
    • (2001) Ann Intern Med , vol.134 , pp. 573-586
    • Santini, V.1    Kantarjian, H.M.2    Issa, J.P.3
  • 7
    • 0037093195 scopus 로고    scopus 로고
    • Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: A study of the Cancer and Leukemia Group B
    • Silverman LR, Demakos EP, Peterson BL, Kornblith AB, Holland JC, Odchimar-Reissig R et al. Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the Cancer and Leukemia Group B. J Clin Oncol 2002; 20: 2429-2440
    • (2002) J Clin Oncol , vol.20 , pp. 2429-2440
    • Silverman, L.R.1    Demakos, E.P.2    Peterson, B.L.3    Kornblith, A.B.4    Holland, J.C.5    Odchimar-Reissig, R.6
  • 8
    • 33646071894 scopus 로고    scopus 로고
    • Decitabine improves patient outcomes in myelodysplastic syndromes: Results of a phase III randomized study
    • Kantarjian H, Issa J-PJ, Rosenfeld CS, Bennett JM, Albitar M, DiPersio J et al. Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer 2006; 106: 1794-1803
    • (2006) Cancer , vol.106 , pp. 1794-1803
    • Kantarjian, H.1    Issa, J.-P.J.2    Rosenfeld, C.S.3    Bennett, J.M.4    Albitar, M.5    DiPersio, J.6
  • 9
    • 62849104641 scopus 로고    scopus 로고
    • Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: A randomised, open-label, phase III study
    • Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009; 10: 223-232
    • (2009) Lancet Oncol , vol.10 , pp. 223-232
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3    Santini, V.4    Finelli, C.5    Giagounidis, A.6
  • 10
    • 77449149373 scopus 로고    scopus 로고
    • Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia
    • Fenaux P, Mufti GJ, Hellström-Lindberg E, Santini V, Gattermann N, Germing U et al. Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia. J Clin Oncol 2010; 28: 562-569
    • (2010) J Clin Oncol , vol.28 , pp. 562-569
    • Fenaux, P.1    Mufti, G.J.2    Hellström-Lindberg, E.3    Santini, V.4    Gattermann, N.5    Germing, U.6
  • 11
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa J-PJ, Garcia-Manero G, Giles FJ, Mannari R, Thomas D, Faderl S et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 2004; 103: 1635-1640
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.-P.J.1    Garcia-Manero, G.2    Giles, F.J.3    Mannari, R.4    Thomas, D.5    Faderl, S.6
  • 12
    • 77952140672 scopus 로고    scopus 로고
    • Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine
    • Blum W, Garzon R, Klisovic RB, Schwind S, Walker A, Geyer S et al. Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine. Proc Natl Acad Sci USA 2010; 107: 7473-7478
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 7473-7478
    • Blum, W.1    Garzon, R.2    Klisovic, R.B.3    Schwind, S.4    Walker, A.5    Geyer, S.6
  • 13
    • 77449149374 scopus 로고    scopus 로고
    • Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia
    • Cashen AF, Schiller GJ, O'Donnell MR, DiPersio JF. Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia. J Clin Oncol 2010; 28: 556-561
    • (2010) J Clin Oncol , vol.28 , pp. 556-561
    • Cashen, A.F.1    Schiller, G.J.2    O'Donnell, M.R.3    DiPersio, J.F.4
  • 14
    • 84864063679 scopus 로고    scopus 로고
    • Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia
    • Kantarjian HM, Thomas XG, Dmoszynska A, Wierzbowska A, Mazur G, Mayer J et al. Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. J Clin Oncol 2012; 30: 2670-2677
    • (2012) J Clin Oncol , vol.30 , pp. 2670-2677
    • Kantarjian, H.M.1    Thomas, X.G.2    Dmoszynska, A.3    Wierzbowska, A.4    Mazur, G.5    Mayer, J.6
  • 15
    • 84869095050 scopus 로고    scopus 로고
    • A randomized study of decitabine versus conventional care for maintenance therapy in patients with acute myeloid leukemia in complete remission [letter]
    • Boumber Y, Kantarjian H, Jorgensen J, Wen S, Faderl S, Castoro R et al. A randomized study of decitabine versus conventional care for maintenance therapy in patients with acute myeloid leukemia in complete remission [letter]. Leukemia 2012; 26: 2428-2431
    • (2012) Leukemia , vol.26 , pp. 2428-2431
    • Boumber, Y.1    Kantarjian, H.2    Jorgensen, J.3    Wen, S.4    Faderl, S.5    Castoro, R.6
  • 16
    • 0035339877 scopus 로고    scopus 로고
    • Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: A Cancer and Leukemia Group B study
    • Mrózek K, Prior TW, Edwards C, Marcucci G, Carroll AJ, Snyder PJ et al. Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer and Leukemia Group B study. J Clin Oncol 2001; 19: 2482-2492
    • (2001) J Clin Oncol , vol.19 , pp. 2482-2492
    • Mrózek, K.1    Prior, T.W.2    Edwards, C.3    Marcucci, G.4    Carroll, A.J.5    Snyder, P.J.6
  • 19
    • 48749119622 scopus 로고    scopus 로고
    • Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: The Cancer and Leukemia Group B experience
    • Mrózek K, Carroll AJ, Maharry K, Rao KW, Patil SR, Pettenati MJ et al. Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: the Cancer and Leukemia Group B experience. Int J Oncol 2008; 33: 239-244
    • (2008) Int J Oncol , vol.33 , pp. 239-244
    • Mrózek, K.1    Carroll, A.J.2    Maharry, K.3    Rao, K.W.4    Patil, S.R.5    Pettenati, M.J.6
  • 20
    • 0035476264 scopus 로고    scopus 로고
    • Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A Cancer and Leukemia Group B study
    • Whitman SP, Archer KJ, Feng L, Baldus C, Becknell B, Carlson BD et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a Cancer and Leukemia Group B study. Cancer Res 2001; 61: 7233-7239
    • (2001) Cancer Res , vol.61 , pp. 7233-7239
    • Whitman, S.P.1    Archer, K.J.2    Feng, L.3    Baldus, C.4    Becknell, B.5    Carlson, B.D.6
  • 21
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C, Steudel C, Mohr B, Schaich M, Schäkel U, Platzbecker U et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood 2002; 99: 4326-4335
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3    Schaich, M.4    Schäkel, U.5    Platzbecker, U.6
  • 22
    • 55549103713 scopus 로고    scopus 로고
    • Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: A Cancer and Leukemia Group B study
    • Marcucci G, Maharry K, Radmacher MD, Mrózek K, Vukosavljevic T, Paschka P et al. Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B study. J Clin Oncol 2008; 26: 5078-5087
    • (2008) J Clin Oncol , vol.26 , pp. 5078-5087
    • Marcucci, G.1    Maharry, K.2    Radmacher, M.D.3    Mrózek, K.4    Vukosavljevic, T.5    Paschka, P.6
  • 23
    • 77449140390 scopus 로고    scopus 로고
    • Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated geneand microRNA-expression signatures: A Cancer and Leukemia Group B study
    • Becker H, Marcucci G, Maharry K, Radmacher MD, Mrózek K, Margeson D et al. Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated geneand microRNA-expression signatures: a Cancer and Leukemia Group B study. J Clin Oncol 2010; 28: 596-604
    • (2010) J Clin Oncol , vol.28 , pp. 596-604
    • Becker, H.1    Marcucci, G.2    Maharry, K.3    Radmacher, M.D.4    Mrózek, K.5    Margeson, D.6
  • 24
    • 77449159028 scopus 로고    scopus 로고
    • Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet
    • Döhner H, Estey EH, Amadori S, Appelbaum FR, Büchner T, Burnett AK et al. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 2010; 115: 453-474
    • (2010) Blood , vol.115 , pp. 453-474
    • Döhner, H.1    Estey, E.H.2    Amadori, S.3    Appelbaum, F.R.4    Büchner, T.5    Burnett, A.K.6
  • 26
    • 0343045296 scopus 로고    scopus 로고
    • Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy-the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: Final report of the European Organization for the Research and Treatment of Cancer and the Dutch-Belgian Hemato-Oncology Cooperative Hovon Group randomized phase III study AML-9
    • Löwenberg B, Suciu S, Archimbaud E, Haak H, Stryckmans P, de Cataldo R et al. Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy-the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: final report of the European Organization for the Research and Treatment of Cancer and the Dutch-Belgian Hemato-Oncology Cooperative Hovon Group randomized phase III study AML-9. J Clin Oncol 1998; 16: 872-881
    • (1998) J Clin Oncol , vol.16 , pp. 872-881
    • Löwenberg, B.1    Suciu, S.2    Archimbaud, E.3    Haak, H.4    Stryckmans, P.5    De Cataldo, R.6
  • 27
    • 84881305790 scopus 로고    scopus 로고
    • A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia
    • Petersdorf SH, Kopecky KJ, Slovak M, Willman C, Nevill T, Brandwein J et al. A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia. Blood 2013; 121: 4854-4860
    • (2013) Blood , vol.121 , pp. 4854-4860
    • Petersdorf, S.H.1    Kopecky, K.J.2    Slovak, M.3    Willman, C.4    Nevill, T.5    Brandwein, J.6
  • 28
    • 77950992731 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin as postremission treatment in AML at 60 years of age or more: Results of a multicenter phase 3 study
    • Löwenberg B, Beck J, Graux C, van Putten W, Schouten HC, Verdonck LF et al. Gemtuzumab ozogamicin as postremission treatment in AML at 60 years of age or more: results of a multicenter phase 3 study. Blood 2010; 115: 2586-2591
    • (2010) Blood , vol.115 , pp. 2586-2591
    • Löwenberg, B.1    Beck, J.2    Graux, C.3    Van Putten, W.4    Schouten, H.C.5    Verdonck, L.F.6
  • 29
    • 84899434062 scopus 로고    scopus 로고
    • Recombinant interleukin-2 in patients aged younger than 60 years with acute myeloid leukemia in first complete remission: Results from Cancer and Leukemia Group B 19808
    • Kolitz JE, George SL, Benson DM Jr, Maharry K, Marcucci G, Vij R et al. Recombinant interleukin-2 in patients aged younger than 60 years with acute myeloid leukemia in first complete remission: results from Cancer and Leukemia Group B 19808. Cancer 2014; 120: 1010-1017
    • (2014) Cancer , vol.120 , pp. 1010-1017
    • Kolitz, J.E.1    George, S.L.2    Benson, D.M.3    Maharry, K.4    Marcucci, G.5    Vij, R.6
  • 30
    • 54449095992 scopus 로고    scopus 로고
    • Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B study 9720
    • Baer MR, George SL, Caligiuri MA, Sanford BL, Bothun SM, Mrózek K et al. Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B study 9720. J Clin Oncol 2008; 26: 4934-4939
    • (2008) J Clin Oncol , vol.26 , pp. 4934-4939
    • Baer, M.R.1    George, S.L.2    Caligiuri, M.A.3    Sanford, B.L.4    Bothun, S.M.5    Mrózek, K.6
  • 31
    • 0033120418 scopus 로고    scopus 로고
    • A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission
    • Cortes JE, Kantarjian HM, O'Brien S, Giles F, Keating MJ, Freireich EJ et al. A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission. Cancer 1999; 85: 1506-1513
    • (1999) Cancer , vol.85 , pp. 1506-1513
    • Cortes, J.E.1    Kantarjian, H.M.2    O'Brien, S.3    Giles, F.4    Keating, M.J.5    Freireich, E.J.6
  • 32
    • 0034114681 scopus 로고    scopus 로고
    • Randomized study of recombinant interleukin-2 after autologous bone marrow transplantation for acute leukemia in first complete remission
    • Blaise D, Attal M, Reiffers J, Michallet M, Bellanger C, Pico JL et al. Randomized study of recombinant interleukin-2 after autologous bone marrow transplantation for acute leukemia in first complete remission. Eur Cytokine Netw 2000; 11: 91-98
    • (2000) Eur Cytokine Netw , vol.11 , pp. 91-98
    • Blaise, D.1    Attal, M.2    Reiffers, J.3    Michallet, M.4    Bellanger, C.5    Pico, J.L.6
  • 33
    • 0031406299 scopus 로고    scopus 로고
    • Immunotherapy with low-dose interleukin-2: Rationale for prevention of immune-deficiency-associated cancer
    • Khatri VP, Baiocchi RA, Bernstein ZP, Caligiuri MA. Immunotherapy with low-dose interleukin-2: rationale for prevention of immune-deficiency-associated cancer. Cancer J Sci Am 1997; 3(Suppl 1): S129-S136
    • (1997) Cancer J Sci Am , vol.3 , pp. S129-S136
    • Khatri, V.P.1    Baiocchi, R.A.2    Bernstein, Z.P.3    Caligiuri, M.A.4
  • 34
    • 53649091606 scopus 로고    scopus 로고
    • Low dose interleukin-2 following intensification therapy with high dose cytarabine for acute myelogenous leukemia in first complete remission
    • Stone RM, DeAngelo DJ, Janosova A, Galinsky I, Canning C, Ritz J et al. Low dose interleukin-2 following intensification therapy with high dose cytarabine for acute myelogenous leukemia in first complete remission. Am J Hematol 2008; 83: 771-777
    • (2008) Am J Hematol , vol.83 , pp. 771-777
    • Stone, R.M.1    DeAngelo, D.J.2    Janosova, A.3    Galinsky, I.4    Canning, C.5    Ritz, J.6
  • 35
    • 33745714215 scopus 로고    scopus 로고
    • Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: Results of a randomized phase 3 trial
    • Brune M, Castaigne S, Catalano J, Gehlsen K, Ho AD, Hofmann WK et al. Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: results of a randomized phase 3 trial. Blood 2006; 108: 88-96
    • (2006) Blood , vol.108 , pp. 88-96
    • Brune, M.1    Castaigne, S.2    Catalano, J.3    Gehlsen, K.4    Ho, A.D.5    Hofmann, W.K.6
  • 36
    • 79959845267 scopus 로고    scopus 로고
    • Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia
    • Buyse M, Squifflet P, Lange BJ, Alonzo TA, Larson RA, Kolitz JE et al. Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia. Blood 2011; 117: 7007-7013
    • (2011) Blood , vol.117 , pp. 7007-7013
    • Buyse, M.1    Squifflet, P.2    Lange, B.J.3    Alonzo, T.A.4    Larson, R.A.5    Kolitz, J.E.6
  • 37
    • 13944269127 scopus 로고    scopus 로고
    • Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia
    • Liu S, Shen T, Huynh L, Klisovic MI, Rush LJ, Ford JL et al. Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia. Cancer Res 2005; 65: 1277-1284.
    • (2005) Cancer Res , vol.65 , pp. 1277-1284
    • Liu, S.1    Shen, T.2    Huynh, L.3    Klisovic, M.I.4    Rush, L.J.5    Ford, J.L.6


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