Rotational thromboelastometry can detect factor XIII deficiency and bleeding diathesis in patients with cirrhosis

Liver International

Volumn 37, Issue 4, 2017, Pages 562-568

  Bedreli, Sotiria ^a   Sowa, Jan Peter ^a   Malek, Saraa ^a   Blomeyer, Sandra ^a   Katsounas, Antonios ^a   Gerken, Guido ^a   Saner, Fuat H ^a   Canbay, Ali ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

cirrhosis; coagulation; factor XIII; rotational thromboelastometry; ROTEM

Indexed keywords

BLOOD CLOTTING FACTOR 13; FIBRINOGEN;

ADULT; ARTICLE; BLEEDING; BLEEDING DISORDER; BLEEDING TENDENCY; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; BLOOD CLOTTING FACTOR 13 DEFICIENCY; CHILD PUGH SCORE; COHORT ANALYSIS; EPISTAXIS; ESOPHAGUS VARICES; FEMALE; HUMAN; HYPERTENSIVE GASTROPATHY; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY RATE; PORTAL HYPERTENSION; RECTUM HEMORRHAGE; RETROSPECTIVE STUDY; STOMACH ANTRUM VASCULAR ECTASIA; STOMACH DISEASE; THROMBOCYTE COUNT; COMPARATIVE STUDY; COMPLICATION; DISEASE PREDISPOSITION; GERMANY; INTERNATIONAL NORMALIZED RATIO; PREDICTIVE VALUE; PROCEDURES; THROMBOELASTOGRAPHY;

DISEASE SUSCEPTIBILITY; FACTOR XIII DEFICIENCY; FEMALE; GERMANY; HEMORRHAGE; HUMANS; INTERNATIONAL NORMALIZED RATIO; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PLATELET COUNT; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; THROMBELASTOGRAPHY;

EID: 84990177606     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.13254     Document Type: Article

References (30)

1. Mammen EF. Coagulation abnormalities in liver disease. Hematol Oncol Clin North Am. 1992;6:1247–1257.
2. Tripodi A, Mannucci PM. The coagulopathy of chronic liver disease. N Engl J Med. 2011;365:147–156.
3. Northup PG, McMahon MM, Ruhl AP, et al. Coagulopathy does not fully protect hospitalized cirrhosis patients from peripheral venous thromboembolism. Am J Gastroenterol. 2006;101:1524–1528.
4. Dabbagh O, Oza A, Prakash S, Sunna R, Saettele TM. Coagulopathy does not protect against venous thromboembolism in hospitalized patients with chronic liver disease. Chest. 2010;137:1145–1149.
5. Nagy JA, Henriksson P, McDonagh J. Biosynthesis of factor XIII B subunit by human hepatoma cell lines. Blood. 1986;68:1272–1279.
6. Ariëns RA, Lai TS, Weisel JW, Greenberg CS, Grant PJ. Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. Blood. 2002;100:743–754.
7. Tacke F, Fiedler K, von Depka M, et al. Clinical and prognostic role of plasma coagulation factor XIII activity for bleeding disorders and 6-year survival in patients with chronic liver disease. Liver Int. 2006;26:173–181.
8. Saner FH, Gieseler RK, Akiz H, Canbay A, Görlinger K. Delicate balance of bleeding and thrombosis in end-stage liver disease and liver transplantation. Digestion. 2013;88:135–144.
9. Bedreli S, Sowa JP, Gerken G, Saner FH, Canbay A. Management of acute-on-chronic liver failure: rotational thromboelastometry may reduce substitution of coagulation factors in liver cirrhosis. Gut. 2016;65:357–358.
10. Carrell NA, Erickson HP, McDonagh J. Electron microscopy and hydrodynamic properties of factor XIII subunits. J Biol Chem. 1989;264:551–556.
11. Bishop PD, Teller DC, Smith RA, Lasser GW, Gilbert T, Seale RL. Expression, purification, and characterization of human factor XIII in Saccharomyces cerevisiae. Biochemistry. 1990;29:1861–1869.
12. Luscher EF. Fibrin-stabilizing factor from thrombocytes [German]. Schweiz Med Wochenschr. 1957;87:1220–1221.
13. Buluk K. An unknown action of blood platelets; preliminary communication. Pol Tyg Lek (Wars). 1955;10:191.
14. Bohn H. Isolation and characterization of the fibrin stabilizing factor from human thrombocytes [German]. Thromb Diath Haemorrh. 1970;23:455–468.
15. Muszbek L, Yee VC, Hevessy Z. Blood coagulation factor XIII: structure and function. Thromb Res. 1999;94:271–305.
16. Theusinger OM, Baulig W, Asmis LM, Seifert B, Spahn DR. In vitro factor XIII supplementation increases clot firmness in Rotation Thromboelastometry (ROTEM). Thromb Haemost. 2010;104:385–391.
17. Nielsen VG, Kirklin JK, Hoogendoorn H, Ellis TC, Holman WL. Thrombelastographic method to quantify the contribution of factor XIII to coagulation kinetics. Blood Coagul Fibrinolysis. 2007;18:145–150.
18. Weber CF, Jambor C, Marquardt M, Gorlinger K, Zwissler B. Thrombelastometric detection of factor XIII deficiency [German]. Anaesthesist. 2008;57:487–490.
19. Weber CF, Sanders JO, Friedrich K, et al. Role of thrombelastometry for the monitoring of factor XIII. A prospective observational study in neurosurgical patients [German]. Hamostaseologie. 2011;31:111–117.
20. Grossmann E, Akyol D, Eder L, et al. Thromboelastometric detection of clotting Factor XIII deficiency in cardiac surgery patients. Transfus Med. 2013;23:407–415.
21. Child CG, Turcotte JG. Surgery and portal hypertension. Major Probl Clin Surg. 1964;1:1–85.
22. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60:646–649.
23. Wiesner R, Edwards E, Freeman R, et al. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology. 2003;124:91–96.
24. Caldwell SH, Hoffman M, Lisman T, et al. Coagulation disorders and hemostasis in liver disease: pathophysiology and critical assessment of current management. Hepatology. 2006;44:1039–1046.
25. Tripodi A, Salerno F, Chantarangkul V, et al. Evidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation tests. Hepatology. 2005;41:553–558.
26. Gorlinger K. Coagulation management during liver transplantation [German]. Hamostaseologie. 2006;26(3 Suppl 1):S64–S76.
27. Tripodi A, Primignani M, Chantarangkul V, et al. The coagulopathy of cirrhosis assessed by thromboelastometry and its correlation with conventional coagulation parameters. Thromb Res. 2009;124:132–136.
28. Nielsen VG, Gurley WQ Jr, Burch TM. The impact of factor XIII on coagulation kinetics and clot strength determined by thrombelastography. Anesth Analg. 2004;99:120–123.
29. Schöchl H, Cotton B, Inaba K, et al. FIBTEM provides early prediction of massive transfusion in trauma. Crit Care. 2011;15:R265.
30. Ghavidel AA, Toutounchi Z, Shahandashti FJ, Mirmesdagh Y. Rotational thromboelastometry in prediction of bleeding after cardiac surgery. Asian Cardiovasc Thorac Ann. 2015;23:525–529.