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Volumn 42, Issue 10, 2016, Pages 1540-1547

FOLFIRI plus cetuximab in patients with liver-limited or non-liver-limited RAS wild-type metastatic colorectal cancer: A retrospective subgroup analysis of the CRYSTAL study

Author keywords

Cetuximab; CRYSTAL; LLD; mCRC; R0 resection; RAS

Indexed keywords

CETUXIMAB; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; K RAS PROTEIN; RAS PROTEIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; KRAS PROTEIN, HUMAN; PROTEIN P21;

EID: 84989883694     PISSN: 07487983     EISSN: 15322157     Source Type: Journal    
DOI: 10.1016/j.ejso.2016.05.038     Document Type: Article
Times cited : (29)

References (21)
  • 1
    • 68949094312 scopus 로고    scopus 로고
    • Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
    • 1 Kopetz, S., Chang, G.J., Overman, M.J., et al. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 27:22 (2009), 3677–3683.
    • (2009) J Clin Oncol , vol.27 , Issue.22 , pp. 3677-3683
    • Kopetz, S.1    Chang, G.J.2    Overman, M.J.3
  • 2
    • 84869024683 scopus 로고    scopus 로고
    • Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors
    • 2 Kanas, G.P., Taylor, A., Primrose, J.N., et al. Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors. Clin Epidemiol 4 (2012), 283–301.
    • (2012) Clin Epidemiol , vol.4 , pp. 283-301
    • Kanas, G.P.1    Taylor, A.2    Primrose, J.N.3
  • 4
    • 84925303820 scopus 로고    scopus 로고
    • Is it worth reorganising cancer services on the basis of multidisciplinary teams (MDTs)? A systematic review of the objectives and organisation of MDTs and their impact on patient outcomes
    • 4 Prades, J., Remue, E., van Hoof, E., Borras, J.M., Is it worth reorganising cancer services on the basis of multidisciplinary teams (MDTs)? A systematic review of the objectives and organisation of MDTs and their impact on patient outcomes. Health Policy 119:4 (2015), 464–474.
    • (2015) Health Policy , vol.119 , Issue.4 , pp. 464-474
    • Prades, J.1    Remue, E.2    van Hoof, E.3    Borras, J.M.4
  • 5
    • 84864677002 scopus 로고    scopus 로고
    • Effect of specialist decision-making on treatment strategies for colorectal liver metastases
    • 5 Jones, R.P., Vauthey, J.N., Adam, R., et al. Effect of specialist decision-making on treatment strategies for colorectal liver metastases. Br J Surg 99:9 (2012), 1263–1269.
    • (2012) Br J Surg , vol.99 , Issue.9 , pp. 1263-1269
    • Jones, R.P.1    Vauthey, J.N.2    Adam, R.3
  • 6
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • 6 Van Cutsem, E., Kohne, C.H., Hitre, E., et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 360:14 (2009), 1408–1417.
    • (2009) N Engl J Med , vol.360 , Issue.14 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 7
    • 79956298812 scopus 로고    scopus 로고
    • Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status
    • 7 Van Cutsem, E., Kohne, C.H., Lang, I., et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol 29:15 (2011), 2011–2019.
    • (2011) J Clin Oncol , vol.29 , Issue.15 , pp. 2011-2019
    • Van Cutsem, E.1    Kohne, C.H.2    Lang, I.3
  • 8
    • 84925324704 scopus 로고    scopus 로고
    • Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer
    • 8 Van Cutsem, E., Lenz, H.J., Kohne, C.H., et al. Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer. J Clin Oncol 33:7 (2015), 692–700.
    • (2015) J Clin Oncol , vol.33 , Issue.7 , pp. 692-700
    • Van Cutsem, E.1    Lenz, H.J.2    Kohne, C.H.3
  • 9
    • 84880736194 scopus 로고    scopus 로고
    • Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases
    • [Epub 2013 Apr 8]
    • 9 Ye, L.C., Liu, T.S., Ren, L., et al. Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases. J Clin Oncol 31:16 (2013), 1931–1938, 10.1200/JCO.2012.44.8308 [Epub 2013 Apr 8].
    • (2013) J Clin Oncol , vol.31 , Issue.16 , pp. 1931-1938
    • Ye, L.C.1    Liu, T.S.2    Ren, L.3
  • 10
    • 73249130298 scopus 로고    scopus 로고
    • Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
    • 10 Folprecht, G., Gruenberger, T., Bechstein, W.O., et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 11:1 (2010), 38–47.
    • (2010) Lancet Oncol , vol.11 , Issue.1 , pp. 38-47
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.O.3
  • 11
    • 84904904651 scopus 로고    scopus 로고
    • Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study)
    • 11 Folprecht, G., Gruenberger, T., Bechstein, W., et al. Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study). Ann Oncol 25:5 (2014), 1018–1025.
    • (2014) Ann Oncol , vol.25 , Issue.5 , pp. 1018-1025
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.3
  • 12
    • 78149469673 scopus 로고    scopus 로고
    • Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial
    • 12 Garufi, C., Torsello, A., Tumolo, S., et al. Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial. Br J Cancer 103:10 (2010), 1542–1547.
    • (2010) Br J Cancer , vol.103 , Issue.10 , pp. 1542-1547
    • Garufi, C.1    Torsello, A.2    Tumolo, S.3
  • 13
    • 84929942462 scopus 로고    scopus 로고
    • Liver resection rate following downsizing chemotherapy with cetuximab in metastatic colorectal cancer: UK retrospective observational study
    • 13 Malik, H., Khan, A.Z., Berry, D.P., et al. Liver resection rate following downsizing chemotherapy with cetuximab in metastatic colorectal cancer: UK retrospective observational study. Eur J Surg Oncol 41:4 (2015), 499–505.
    • (2015) Eur J Surg Oncol , vol.41 , Issue.4 , pp. 499-505
    • Malik, H.1    Khan, A.Z.2    Berry, D.P.3
  • 14
    • 84920833509 scopus 로고    scopus 로고
    • Tumour biology of colorectal liver metastasis is a more important factor in survival than surgical margin clearance in the era of modern chemotherapy regimens
    • 14 Truant, S., Sequier, C., Leteurtre, E., et al. Tumour biology of colorectal liver metastasis is a more important factor in survival than surgical margin clearance in the era of modern chemotherapy regimens. HPB (Oxford) 17:2 (2015), 176–184.
    • (2015) HPB (Oxford) , vol.17 , Issue.2 , pp. 176-184
    • Truant, S.1    Sequier, C.2    Leteurtre, E.3
  • 15
    • 84879124807 scopus 로고    scopus 로고
    • Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy
    • 15 Andreou, A., Aloia, T.A., Brouquet, A., et al. Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy. Ann Surg 257:6 (2013), 1079–1088.
    • (2013) Ann Surg , vol.257 , Issue.6 , pp. 1079-1088
    • Andreou, A.1    Aloia, T.A.2    Brouquet, A.3
  • 16
    • 84989854829 scopus 로고    scopus 로고
    • CALGB/SWOG 5: phase III trial of FOLFIRI or mFOLFOX6 with bevacizumab or cetuximab for patients with expanded RAS analyses in untreated metastatic adenocarcinoma of the colon or rectum, ESMO.
    • 16 Lenz H, Niedzwiecki D, Innocenti F et al. CALGB/SWOG 80405: phase III trial of FOLFIRI or mFOLFOX6 with bevacizumab or cetuximab for patients with expanded RAS analyses in untreated metastatic adenocarcinoma of the colon or rectum, ESMO; 2014.
    • (2014)
    • Lenz, H.1    Niedzwiecki, D.2    Innocenti, F.3
  • 17
    • 84989914176 scopus 로고    scopus 로고
    • Fischer von Weikersthal L, Decker T. Independent radiological evaluation of objective response, early tumor shrinkage, and depth of response in FIRE-3 (AIO KRK-0306) in the final RAS evaluable population, ESMO; [abstr LBA11].
    • 17 Stintzing S, Modest DP, Fischer von Weikersthal L, Decker T. Independent radiological evaluation of objective response, early tumor shrinkage, and depth of response in FIRE-3 (AIO KRK-0306) in the final RAS evaluable population, ESMO; 2014 [abstr LBA11].
    • (2014)
    • Stintzing, S.1    Modest, D.P.2
  • 18
    • 84908573757 scopus 로고    scopus 로고
    • FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial
    • 18 Heinemann, V., von Weikersthal, L.F., Decker, T., et al. FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial. Lancet Oncol 15:10 (2014), 1065–1075.
    • (2014) Lancet Oncol , vol.15 , Issue.10 , pp. 1065-1075
    • Heinemann, V.1    von Weikersthal, L.F.2    Decker, T.3
  • 19
    • 84907027361 scopus 로고    scopus 로고
    • CALGB/SWOG 80405: phase III trial of irinotecan/5-FU/leucovorin (FOLFIRI) or oxaliplatin/5-FU/leucovorin (mFOLFOX6) with bevacizumab (BV) or cetuximab (CET) for patients (pts) with KRAS wild-type (wt) untreated metastatic adenocarcinoma of the colon or rectum (MCRC)
    • 5s, suppl; abstr LBA3
    • 19 Venook, A.P., Niedzwiecki, D., Lenz, H.-J., et al. CALGB/SWOG 80405: phase III trial of irinotecan/5-FU/leucovorin (FOLFIRI) or oxaliplatin/5-FU/leucovorin (mFOLFOX6) with bevacizumab (BV) or cetuximab (CET) for patients (pts) with KRAS wild-type (wt) untreated metastatic adenocarcinoma of the colon or rectum (MCRC). J Clin Oncol, 32, 2014 5s, suppl; abstr LBA3.
    • (2014) J Clin Oncol , vol.32
    • Venook, A.P.1    Niedzwiecki, D.2    Lenz, H.-J.3
  • 20
    • 84907023716 scopus 로고    scopus 로고
    • Treatment outcome according to tumor RAS mutation status in OPUS study patients with metastatic colorectal cancer (mCRC) randomized to FOLFOX4 with/without cetuximab
    • 2014 (suppl; abstr 3505).
    • 20 Bokemeyer, C., Kohne, C.-H., Ciardiello, F., et al. Treatment outcome according to tumor RAS mutation status in OPUS study patients with metastatic colorectal cancer (mCRC) randomized to FOLFOX4 with/without cetuximab. J Clin Oncol, 32(5s), 2014 2014 (suppl; abstr 3505).
    • (2014) J Clin Oncol , vol.32 , Issue.5s
    • Bokemeyer, C.1    Kohne, C.-H.2    Ciardiello, F.3
  • 21
    • 79956310674 scopus 로고    scopus 로고
    • Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study
    • 21 Bokemeyer, C., Bondarenko, I., Hartmann, J.T., et al. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol 22:7 (2011), 1535–1546.
    • (2011) Ann Oncol , vol.22 , Issue.7 , pp. 1535-1546
    • Bokemeyer, C.1    Bondarenko, I.2    Hartmann, J.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.