Ammonia‐induced brain edema and intracranial hypertension in rats after portacaval anastomosis

Hepatology

Volumn 19, Issue 6, 1994, Pages 1437-1444

  Blei, Andres T ^a   Olafsson, Sigurdur ^a   Therrien, Guy ^b   Butterworth, Roger F ^b  

^a JESSE BROWN VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; AMMONIA; AMMONIUM ACETATE; GLUTAMIC ACID; GLUTAMINE; METHIONINE SULFOXIMINE;

AMINO ACID ANALYSIS; ANIMAL EXPERIMENT; ARTICLE; BRAIN EDEMA; BRAIN HERNIA; BRAIN WATER; CAUSE OF DEATH; CONTROLLED STUDY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; LIVER FAILURE; MALE; NONHUMAN; PORTOCAVAL SHUNT; PRIORITY JOURNAL; RAT;

AMMONIA; ANIMALS; BLOOD PRESSURE; BODY WATER; BRAIN EDEMA; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMATES; GLUTAMINE; INTRACRANIAL PRESSURE; MALE; METHIONINE SULFOXIMINE; PORTACAVAL SHUNT, SURGICAL; PSEUDOTUMOR CEREBRI; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84989509425     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.1840190619     Document Type: Article

References (35)

1. Early indicators of prognosis in fulminant hepatic failure
2. Fulminant hepatic failure and orthotopic liver transplantation
3. Brain edema in rabbits with galactosamine‐induced fulminant hepatitis. Regional differences and effects on intracranial pressure
4. Effect of body temperature on brain edema and encephalopathy in the rat after hepatic devascularization
5. Cerebral edema and intracranial hypertension in acute liver failure: distinct aspects of the same problem
6. Changes in the blood‐brain barrier in hepatic coma after hepatectomy in the rat
7. Increased blood‐brain transfer in a rabbit model of acute liver failure
8. Brain edem
9. Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure
10. Controlled trial of dexametasone and mannitol for the cerebral oedema of fulminant hepatic failure
11. +‐ATPase activity by serum from patients with fulminant hepatic failure
12. Digoxin‐like immunoreactive substances in severe acute liver disease due to viral hepatitis and paracetamol overdose
13. Hepatic encephalopathy [Letter]
14. Acute hyperammonemia in the young primate: physiologic and neuropathologic correlates
15. Interactions between glutamine metabolism and cell‐volume regulation in perfused rat liver
16. Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats
17. Monitoring of neurotransmitter amino acids by means of an indwelling cisterna magna catheter: a comparison of two rodent models of fulminant hepatic failure
18. Ammonia and related amino acids in the pathogenesis of brain edema in acute ischemic liver failure in rats
19. Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice
20. A simple gravimetric technique for measurement of cerebral edema
21. Amino acid changes in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy
22. Hyperammonemia does not impair brain function in the absence of net glutamine synthesis
23. Cerebral blood flow and the hyperdynamic circulation of rats after portacaval anastomosis
24. Blood/brain barrier and brain edema in ammonia intoxication
25. Cerebral vasodilatation and intracranial pressure in rabbits with hepatic encephalopathy
26. Intracellular pH rises and astrocytes swell after portacaval anastomosis in rats
27. Ammonia‐induced swelling of rat cerebral cortical slices: implications for the pathogenesis of brain edema in acute hepatic failure
28. Synpatic transmission in ammonia intoxication
29. Early establishment of cerebral dysfunction after portacaval shunting
30. Effects of an inhibitor of glutamine synthetase (methionine sulfoximine) on ammonia toxicity and metabolism
31. Glial and neuronal changes in experimental hepatic encephalopathy
32. 15N]glutamine: implications for the glutamine‐glutamate cycle
33. 2 responsivity by glutamine synthesis inhibition in hyperammonemic rats
34. Intravenous glutamate enhances edema formation after a freezing lesion
35. Intracranial pressure waves and intracranial hypertension in rats with ischemic fulminant hepatic failure