Real-time point of care microcirculatory assessment of shock: Design, rationale and application of the point of care microcirculation (POEM) tool

Critical Care

Volumn 20, Issue 1, 2016, Pages

  Naumann, David N ^a   Mellis, Clare ^b   Husheer, Shamus L G ^c   Hopkins, Philip ^b   Bishop, Jon ^a   Midwinter, Mark J ^a   Hutchings, Sam D ^b  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c Heartfelt Technologies Ltd   (United Kingdom)

Author keywords

Circulation; Hemorrhage; Microcirculation; Point of care; Sepsis; Shock

Indexed keywords

ARTICLE; CARDIOVASCULAR PARAMETERS; CLINICAL ARTICLE; CLINICAL ASSESSMENT TOOL; COMPUTER ANALYSIS; CORRELATION COEFFICIENT; HEALTH CARE PERSONNEL; HUMAN; INTERNAL CONSISTENCY; MEDICAL EXPERT; MICROCIRCULATORY FLOW INDEX; MICROCIRCULATORY HETEROGENEITY INDEX; NON INVASIVE MEASUREMENT; PERFUSED VESSEL DENSITY; POINT OF CARE MICROCIRCULATION; PRIORITY JOURNAL; PROPORTION OF PERFUSED VESSEL; SCORING SYSTEM; SHOCK; TOTAL VESSEL DENSITY; VIDEO MICROSCOPY; BLOOD FLOW VELOCITY; CLINICAL TRIAL; COMPUTER SYSTEM; MICROCIRCULATION; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; POINT OF CARE SYSTEM; PROCEDURES; RANDOMIZATION; SEVERITY OF ILLNESS INDEX; SINGLE BLIND PROCEDURE; STANDARDS;

BLOOD FLOW VELOCITY; COMPUTER SYSTEMS; HEALTH PERSONNEL; HUMANS; MICROCIRCULATION; MICROSCOPY, VIDEO; POINT-OF-CARE SYSTEMS; RANDOM ALLOCATION; SEVERITY OF ILLNESS INDEX; SHOCK; SINGLE-BLIND METHOD;

EID: 84989322147     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-016-1492-1     Document Type: Article

References (19)

1. Ince C. Hemodynamic coherence and the rationale for monitoring the microcirculation. Crit Care. 2015;19 Suppl 3:S8.
2. Dubin A, Pozo MO, Casabella CA, Palizas Jr F, Murias G, Moseinco MC, et al. Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study. Crit Care. 2009;13(3):R92.
3. De Backer D, Donadello K, Sakr Y, Ospina-Tascon G, Salgado D, Scolletta S, et al. Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome. Crit Care Med. 2013;41(3):791-9.
4. Tachon G, Harrois A, Tanaka S, Kato H, Huet O, Pottecher J, et al. Microcirculatory alterations in traumatic hemorrhagic shock. Crit Care Med. 2014;42(6):1433-41.
5. Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM. Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial. Crit Care. 2010;14(4):R151.
6. Trzeciak S, McCoy JV, Phillip Dellinger R, Arnold RC, Rizzuto M, Abate NL, et al. Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis. Intensive Care Med. 2008;34(12):2210-7.
7. De Backer D, Hollenberg S, Boerma C, Goedhart P, Buchele G, Ospina-Tascon G, et al. How to evaluate the microcirculation: report of a round table conference. Crit Care. 2007;11(5):R101.
8. Hutchings S, Naumann DN, Harris T, Wendon J, Midwinter MJ. Observational study of the effects of traumatic injury, haemorrhagic shock and resuscitation on the microcirculation: a protocol for the MICROSHOCK study. BMJ Open. 2016;6(3):e010893.
9. Hutchings S, Watts S, Kirkman E. The Cytocam video microscope. A new method for visualising the microcirculation using Incident Dark Field technology. Clin Hemorheol Microcirc. 2016;62(3):261-71.
10. Massey MJ, Larochelle E, Najarro G, Karmacharla A, Arnold R, Trzeciak S, et al. The microcirculation image quality score: development and preliminary evaluation of a proposed approach to grading quality of image acquisition for bedside videomicroscopy. J Crit Care. 2013;28(6):913-7.
11. Boerma EC, Mathura KR, van der Voort PH, Spronk PE, Ince C. Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study. Crit Care. 2005;9(6):R601-6.
12. Arnold RC, Parrillo JE, Phillip Dellinger R, Chansky ME, Shapiro NI, Lundy DJ, et al. Point-of-care assessment of microvascular blood flow in critically ill patients. Intensive Care Med. 2009;35(10):1761-6.
13. van der Voort PH, van Zanten M, Bosman RJ, van Stijn I, Wester JP, van Raalte R, et al. Testing a conceptual model on early opening of the microcirculation in severe sepsis and septic shock: a randomised controlled pilot study. Eur J Anaesthesiol. 2015;32(3):189-98.
14. Lima A, Lopez A, van Genderen ME, Hurtado FJ, Angulo M, Grignola JC, et al. Interrater Reliability and Diagnostic Performance of Subjective Evaluation of Sublingual Microcirculation Images by Physicians and Nurses: A Multicenter Observational Study. Shock. 2015;44(3):239-44.
15. Tanaka S, Harrois A, Nicolai C, Flores M, Hamada S, Vicaut E, et al. Qualitative real-time analysis by nurses of sublingual microcirculation in intensive care unit: the MICRONURSE study. Crit Care. 2015;19:388.
16. Marini JJ, Gattinoni L, Ince C, Kozek-Langenecker S, Mehta RL, Pichard C, et al. A few of our favorite unconfirmed ideas. Crit Care. 2015;19 Suppl 3:S1.
17. Naumann DN, Midwinter MJ, Hutchings S. Venous-to-arterial CO2 differences and the quest for bedside point-of-care monitoring to assess the microcirculation during shock. Ann Translat Med. 2016;4(2):37.
18. Kozar RA, Peng Z, Zhang R, Holcomb JB, Pati S, Park P, et al. Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock. Anesth Analg. 2011;112(6):1289-95.
19. Pati S, Potter DR, Baimukanova G, Farrel DH, Holcomb JB, Schreiber MA. Modulating the endotheliopathy of trauma: factor concentrate versus fresh frozen plasma. J Trauma Acute Care Surg. 2016;80(4):576-85.