Expression of Galα(1,3)Gal by porcine islet cells and its relevance to xenotransplantation

Xenotransplantation

Volumn 2, Issue 3, 1995, Pages 139-142

  McKenzie, Ian F C ^a   Koulmanda, Maria ^b   Sandrin, Mauro S ^a   Mandel, Tom E ^b  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Gal (1,3)Gal epitope; islet cell transplantation

Indexed keywords

EID: 84989026760     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.1995.tb00081.x     Document Type: Article

References (13)

1. How important are anti‐Galα(1,3)Gal antibodies in pig‐to‐human xenotransplants?
2. Identification of α‐galactosyl and other carbohydrate epitopes that are bound by human anti‐pig antibodies: relevance to discordant xenografting in man
3. Interaction of the natural anti‐Gal antibody with α‐galactosyl epitope: A major obstacle for xenotransplantation in humans
4. Biochemical studies of pig xenoantigens detected by naturally occurring human antibodies and the galactose α(1‐3)galactose reactive lectin
5. Galα(1,3)Gal is the major xenoepitope expressed on pig endothelial cells recognised by naturally occurring cytotoxic human antibodies
6. Transplantation of porcine fetal pancreas to diabetic patients
7. Distribution of the major xenoantigen (gal(α1‐3)gal) for pig to human xenografts
8. Activation of UDP‐galactose: Globotriaosyl‐ceramide α1‐3galactosyltransferase during PC12D cell differentiation induced by galactosylceramide
9. A cloned human cDNA determines expression of a mouse stage‐specific embryonic antigen and the Lewis blood group α(1,3/1,4) fucosyltransferase
10. Immediate destruction of xenogeneic islets in a primate model
11. Fetal pig islets in NOD‐mice and cynomologous monkeys