Loss of Trex1 in dendritic cells is sufficient to trigger systemic autoimmunity

Journal of Immunology

Volumn 197, Issue 6, 2016, Pages 2157-2166

  Peschke, Katrin ^a   Achleitner, Martin ^a   Frenzel, Kathrin ^b   Gerbaulet, Alexander ^a   Remzi Ada, Servi ^a   Zeller, Nicolas ^b   Lienenklaus, Stefan ^c,d   Lesche, Mathias ^e   Poulet, Claire ^a   Naumann, Ronald ^f   Dahl, Andreas ^e   Ravens, Ursula ^a   Günther, Claudia ^a   Müller, Werner ^g   Knobeloch, Klaus Peter ^b   Prinz, Marco ^b   Roers, Axel ^a   Behrendt, Rayk ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^e DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^f MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^g UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC GMP; DNA; EXTRACHROMOSOMAL DNA; INTERFERON; NUCLEIC ACID; PROTEIN; TREX1 PROTEIN; UNCLASSIFIED DRUG; CD19 ANTIGEN; CD19 ANTIGEN, MOUSE; EXODEOXYRIBONUCLEASE; PHOSPHOPROTEIN; THREE PRIME REPAIR EXONUCLEASE 1;

ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; AUTOIMMUNITY; B LYMPHOCYTE; CARDIAC MUSCLE CELL; CELLS BY BODY ANATOMY; CONTROLLED STUDY; DENDRITIC CELL; HEMATOPOIETIC SYSTEM; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; KERATINOCYTE; MICROGLIA; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSOR; ANIMAL; BIOSYNTHESIS; BRAIN; C57BL MOUSE; DEFICIENCY; IMMUNOLOGY; KNOCKOUT MOUSE; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD19; AUTOIMMUNITY; B-LYMPHOCYTES; BRAIN; DENDRITIC CELLS; EXODEOXYRIBONUCLEASES; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOPROTEINS;

EID: 84988958814     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600722     Document Type: Article

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