메뉴 건너뛰기




Volumn 39, Issue 10, 2016, Pages 1664-1670

Fall in C-peptide during first 4 years from diagnosis of type 1 diabetes: Variable relation to age, HbA1c, and insulin dose

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; HEMOGLOBIN A1C; INSULIN; ANTIDIABETIC AGENT; GLYCOSYLATED HEMOGLOBIN;

EID: 84988934374     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc16-0360     Document Type: Article
Times cited : (118)

References (26)
  • 1
    • 57749176852 scopus 로고    scopus 로고
    • Type 1 Diabetes TrialNet Study Group. Type. 1 Diabetes TrialNet-an international collaborative clinical trials network
    • Skyler JS, Greenbaum CJ, Lachin JM, et al. Type 1 Diabetes TrialNet Study Group. Type 1 Diabetes TrialNet-an international collaborative clinical trials network. Ann N Y Acad Sci 2008; 1150:14-24
    • (2008) Ann N y Acad Sci , vol.1150 , pp. 14-24
    • Skyler, J.S.1    Greenbaum, C.J.2    Lachin, J.M.3
  • 2
    • 55249085210 scopus 로고    scopus 로고
    • Mixed-meal tolerance test versus glucagon stimulation test for the assessment of betacell function in therapeutic trials in type 1 diabetes
    • Type 1 Diabetes Trial Net Research Group; European C-Peptide Trial Study Group
    • Greenbaum CJ, Mandrup-Poulsen T, McGee PF, et al.; Type 1 Diabetes Trial Net Research Group; European C-Peptide Trial Study Group. Mixed-meal tolerance test versus glucagon stimulation test for the assessment of betacell function in therapeutic trials in type 1 diabetes. Diabetes Care 2008;31:1966-1971
    • (2008) Diabetes Care , vol.31 , pp. 1966-1971
    • Greenbaum, C.J.1    Mandrup-Poulsen, T.2    Mc Gee, P.F.3
  • 3
    • 9144268894 scopus 로고    scopus 로고
    • C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β-cell function: Report of an ADA workshop, 21-22 October 2001
    • Palmer JP, Fleming GA, Greenbaum CJ, et al. C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β-cell function: Report of an ADA workshop, 21-22 October 2001. Diabetes 2004;53:250-264
    • (2004) Diabetes , vol.53 , pp. 250-264
    • Palmer, J.P.1    Fleming, G.A.2    Greenbaum, C.J.3
  • 4
    • 68149136902 scopus 로고    scopus 로고
    • New definition for the partial remission period in children and adolescents with type. 1 diabetes
    • Hvidoere Study Group on Childhood Diabetes
    • Mortensen HB, Hougaard P, Swift P, et al.; Hvidoere Study Group on Childhood Diabetes. New definition for the partial remission period in children and adolescents with type 1 diabetes. Diabetes Care 2009;32:1384-1390
    • (2009) Diabetes Care , vol.32 , pp. 1384-1390
    • Mortensen, H.B.1    Hougaard, P.2    Swift, P.3
  • 5
    • 80051471700 scopus 로고    scopus 로고
    • Protégé Trial Investigators. Teplizumab for treatment of type. 1 diabetes (Protégé study): 1-year results from a randomised, placebocontrolled trial
    • Sherry N, Hagopian W, Ludvigsson J, et al.; Protégé Trial Investigators. Teplizumab for treatment of type 1 diabetes (Protegé study): 1-year results from a randomised, placebocontrolled trial. Lancet 2011;378:487-497
    • (2011) Lancet , vol.378 , pp. 487-497
    • Sherry, N.1    Hagopian, W.2    Ludvigsson, J.3
  • 6
    • 84878300647 scopus 로고    scopus 로고
    • Interleukin-1 antagonism in type 1 diabetes of recent onset: Two multicentre, randomised, double-blind, placebo-controlled trials
    • Type 1 Diabetes Trial Net Canakinumab Study Group; AIDA Study Group
    • Moran A, Bundy B, Becker DJ, et al.; Type 1 Diabetes Trial Net Canakinumab Study Group; AIDA Study Group. Interleukin-1 antagonism in type 1 diabetes of recent onset: Two multicentre, randomised, double-blind, placebo-controlled trials. Lancet 2013;381:1905-1915
    • (2013) Lancet , vol.381 , pp. 1905-1915
    • Moran, A.1    Bundy, B.2    Becker, D.J.3
  • 7
    • 79960743608 scopus 로고    scopus 로고
    • Antigenbased therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: A randomised double-blind trial
    • Type 1 Diabetes Trial Net GAD Study Group
    • Wherrett DK, Bundy B, Becker DJ, et al.; Type 1 Diabetes Trial Net GAD Study Group. Antigenbased therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: A randomised double-blind trial. Lancet 2011;378:319-327
    • (2011) Lancet , vol.378 , pp. 319-327
    • Wherrett, D.K.1    Bundy, B.2    Becker, D.J.3
  • 8
    • 79960912796 scopus 로고    scopus 로고
    • Co-stimulation modulation with abatacept in patients with recent-onset type. 1 diabetes: A randomised, double-blind, placebo-controlled trial
    • Type 1 Diabetes TrialNet Abatacept Study Group
    • Orban T, Bundy B, Becker DJ, et al.; Type 1 Diabetes TrialNet Abatacept Study Group. Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: A randomised, double-blind, placebo-controlled trial. Lancet 2011;378:412-419
    • (2011) Lancet , vol.378 , pp. 412-419
    • Orban, T.1    Bundy, B.2    Becker, D.J.3
  • 9
    • 77950636402 scopus 로고    scopus 로고
    • Failure to preserve β-cell function with mycophenolate mofetil and daclizumab combined therapy in patientswith new-onset type 1 diabetes
    • Type 1 Diabetes TrialNet MMF/DZB Study Group
    • Gottlieb PA, Quinlan S, Krause-Steinrauf H, et al.; Type 1 Diabetes TrialNet MMF/DZB Study Group.Failure to preserve β-cell function with mycophenolate mofetil and daclizumab combined therapy in patientswith new-onset type 1 diabetes. Diabetes Care 2010;33:826-832
    • (2010) Diabetes Care , vol.33 , pp. 826-832
    • Gottlieb, P.A.1    Quinlan, S.2    Krause-Steinrauf, H.3
  • 10
    • 70449480577 scopus 로고    scopus 로고
    • Rituximab, B-lymphocyte depletion, and preservation of β-cell function
    • Type 1 Diabetes TrialNet Anti-CD20 Study Group
    • Pescovitz MD, Greenbaum CJ, Krause- Steinrauf H, et al.; Type 1 Diabetes TrialNet Anti- CD20 Study Group.Rituximab, B-lymphocyte depletion, and preservation of β-cell function. N Engl J Med 2009;361:2143-2152
    • (2009) N Engl J Med , vol.361 , pp. 2143-2152
    • Pescovitz, M.D.1    Greenbaum, C.J.2    Krause-Steinrauf, H.3
  • 11
    • 20044375937 scopus 로고    scopus 로고
    • A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
    • Herold KC, Gitelman SE, Masharani U, et al. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 2005;54:1763-1769
    • (2005) Diabetes , vol.54 , pp. 1763-1769
    • Herold, K.C.1    Gitelman, S.E.2    Masharani, U.3
  • 12
    • 0041666293 scopus 로고    scopus 로고
    • β-cell function and the development of diabetes- related complications in the Diabetes Control and Complications Trial
    • Steffes MW, Sibley S, Jackson M, ThomasW. β-cell function and the development of diabetes- related complications in the Diabetes Control and Complications Trial. Diabetes Care 2003;26: 832-836
    • (2003) Diabetes Care , vol.26 , pp. 832-836
    • Steffes, M.W.1    Sibley, S.2    Jackson, M.3    Thomas, W.4
  • 13
    • 84893119634 scopus 로고    scopus 로고
    • Impact of C-peptide preservation on metabolic and clinical outcomes in the Diabetes Control and Complications Trial
    • DCCT/EDIC Research Group
    • Lachin JM, Mc Gee P, Palmer JP; DCCT/EDIC Research Group. Impact of C-peptide preservation on metabolic and clinical outcomes in the Diabetes Control and Complications Trial. Diabetes 2014;63:739-748
    • (2014) Diabetes , vol.63 , pp. 739-748
    • Lachin, J.M.1    Mc Gee, P.2    Palmer, J.P.3
  • 14
    • 0032055459 scopus 로고    scopus 로고
    • Effect of intensive therapy on residual β-cell function in patients with type 1 diabetes in the diabetes control and complications trial: A randomized, controlled trial
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. Effect of intensive therapy on residual β-cell function in patients with type 1 diabetes in the diabetes control and complications trial: A randomized, controlled trial. Ann Intern Med 1998;128:517-523
    • (1998) Ann Intern Med , vol.128 , pp. 517-523
  • 15
    • 84920052627 scopus 로고    scopus 로고
    • Demonstration of an intrinsic relationship between endogenous C-peptide concentration and determinants of glycemic control in type 1 diabetes following islet transplantation
    • Brooks AM, OramR, Home P, Steen N, Shaw JA. Demonstration of an intrinsic relationship between endogenous C-peptide concentration and determinants of glycemic control in type 1 diabetes following islet transplantation. Diabetes Care 2015;38:105-112
    • (2015) Diabetes Care , vol.38 , pp. 105-112
    • Brooks, A.M.1    Oram, R.2    Home, P.3    Steen, N.4    Shaw, J.A.5
  • 16
    • 84868624334 scopus 로고    scopus 로고
    • Continuous glucosemonitoring after islet transplantation in type 1 diabetes: An excellent graft function (b-score greater than 7) is required to abrogate hyperglycemia, whereas a minimal function is necessary to suppress severe hypoglycemia (b-score greater than 3)
    • Vantyghem MC, Raverdy V, Balavoine AS, et al. Continuous glucosemonitoring after islet transplantation in type 1 diabetes: An excellent graft function (b-score greater than 7) is required to abrogate hyperglycemia, whereas a minimal function is necessary to suppress severe hypoglycemia (b-score greater than 3). J Clin Endocrinol Metab 2012;97:E2078-E2083
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. E2078-E2083
    • Vantyghem, M.C.1    Raverdy, V.2    Balavoine, A.S.3
  • 17
    • 0141964474 scopus 로고    scopus 로고
    • GRAGIL Group. Reduction of blood glucose variability in type 1 diabetic patients treated by pancreatic islet transplantation: Interest of continuous glucose monitoring
    • Kessler L, Passemard R, Oberholzer J, et al.; GRAGIL Group. Reduction of blood glucose variability in type 1 diabetic patients treated by pancreatic islet transplantation: Interest of continuous glucose monitoring. Diabetes Care 2002;25:2256-2262
    • (2002) Diabetes Care , vol.25 , pp. 2256-2262
    • Kessler, L.1    Passemard, R.2    Oberholzer, J.3
  • 18
    • 84864381301 scopus 로고    scopus 로고
    • Fall in C-peptide during first 2 years from diagnosis: Evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data
    • Type 1 Diabetes TrialNet Study Group
    • Greenbaum CJ, Beam CA, Boulware D, et al.; Type 1 Diabetes TrialNet Study Group.Fall in C-peptide during first 2 years from diagnosis: Evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data. Diabetes 2012;61:2066-2073
    • (2012) Diabetes , vol.61 , pp. 2066-2073
    • Greenbaum, C.J.1    Beam, C.A.2    Boulware, D.3
  • 19
    • 84930760699 scopus 로고    scopus 로고
    • T1D Exchange Clinic Network. Prevalence of detectable C-peptide according to age at diagnosis and duration of type 1 diabetes
    • Davis AK, DuBose SN, Haller MJ, et al.; T1D Exchange Clinic Network.Prevalence of detectable C-peptide according to age at diagnosis and duration of type 1 diabetes. Diabetes Care 2015; 38:476-481
    • (2015) Diabetes Care , vol.38 , pp. 476-481
    • Davis, A.K.1    DuBose, S.N.2    Haller, M.J.3
  • 21
    • 0022619110 scopus 로고
    • Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset. Results of a multicentre double-blind trial
    • Feutren G, Papoz L, Assan R, et al. Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset. Results of a multicentre double-blind trial. Lancet 1986;2:119-124
    • (1986) Lancet , vol.2 , pp. 119-124
    • Feutren, G.1    Papoz, L.2    Assan, R.3
  • 22
    • 84939218518 scopus 로고    scopus 로고
    • Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
    • Rigby MR, Harris KM, Pinckney A, et al. Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. J Clin Invest 2015;125:3285-3296
    • (2015) J Clin Invest , vol.125 , pp. 3285-3296
    • Rigby, M.R.1    Harris, K.M.2    Pinckney, A.3
  • 23
    • 84887621720 scopus 로고    scopus 로고
    • T1DAL Study Team.Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial
    • Rigby MR, DiMeglio LA, Rendell MS, et al.; T1DAL Study Team.Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Diabetes Endocrinol 2013;1:284-294
    • (2013) Lancet Diabetes Endocrinol , vol.1 , pp. 284-294
    • Rigby, M.R.1    DiMeglio, L.A.2    Rendell, M.S.3
  • 24
    • 84887052291 scopus 로고    scopus 로고
    • Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders
    • AbATE Study Team
    • Herold KC, Gitelman SE, Ehlers MR, et al.; AbATE Study Team.Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: Metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes 2013;62:3766-3774
    • (2013) Diabetes , vol.62 , pp. 3766-3774
    • Herold, K.C.1    Gitelman, S.E.2    Ehlers, M.R.3
  • 25
    • 84893118586 scopus 로고    scopus 로고
    • B-lymphocyte depletion with rituximab and β-cell function: Two-year results
    • Type 1 Diabetes TrialNet Anti-CD20 Study Group
    • Pescovitz MD, Greenbaum CJ, Bundy B, et al.; Type 1 Diabetes TrialNet Anti-CD20 Study Group. B-lymphocyte depletion with rituximab and β-cell function: Two-year results. Diabetes Care 2014;37:453-459
    • (2014) Diabetes Care , vol.37 , pp. 453-459
    • Pescovitz, M.D.1    Greenbaum, C.J.2    Bundy, B.3
  • 26
    • 84897851090 scopus 로고    scopus 로고
    • Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: Followup 1 year after cessation of treatment
    • Type 1 Diabetes TrialNet Abatacept Study Group
    • Orban T, Bundy B, Becker DJ, et al.; Type 1 Diabetes TrialNet Abatacept Study Group.Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: Followup 1 year after cessation of treatment. Diabetes Care 2014;37:1069-1075
    • (2014) Diabetes Care , vol.37 , pp. 1069-1075
    • Orban, T.1    Bundy, B.2    Becker, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.