Salience Network Connectivity in Autism Is Related to Brain and Behavioral Markers of Sensory Overresponsivity

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 55, Issue 7, 2016, Pages 618-626.e1

  Green, Shulamite A ^a   Hernandez, Leanna ^a   Bookheimer, Susan Y ^a   Dapretto, Mirella ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

autism spectrum disorders; fMRI; resting state; salience network; sensory overresponsivity

Indexed keywords

ADULT; AMYGDALA; ANTERIOR INSULA; ANXIETY; ARTICLE; AUDITORY CORTEX; AUDITORY STIMULATION; AUTISM; AUTISM DIAGNOSTIC OBSERVATION SCHEDULE; BRAIN REGION; CHILD; CHILD BEHAVIOR; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; ECHO PLANAR IMAGING; ELECTROENCEPHALOGRAM; FEMALE; FRONTAL CORTEX; FUNCTIONAL CONNECTIVITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; FUSIFORM GYRUS; HUMAN; INSULA; INTELLIGENCE QUOTIENT; LINGUAL GYRUS; MALE; MIDDLE TEMPORAL GYRUS; NUCLEAR MAGNETIC RESONANCE SCANNER; OCCIPITAL CORTEX; POSTCENTRAL GYRUS; PRECUNEUS; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; RIGHT HIPPOCAMPUS; SALIENCE NETWORK; SENSORY OVERRESPONSIVITY; SENSORY SYSTEM; SOMATOSENSORY CORTEX; STRIATE CORTEX; SUPERIOR FRONTAL GYRUS; SUPERIOR PARIETAL LOBULE; SUPERIOR TEMPORAL GYRUS; SUPPLEMENTARY MOTOR AREA; SUPRAMARGINAL GYRUS; TACTILE STIMULATION; TIME SERIES ANALYSIS; WECHSLER INTELLIGENCE SCALE FOR CHILDREN; ADOLESCENT; BRAIN CORTEX; COMPLICATION; CONNECTOME; DIAGNOSTIC IMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; SENSORY DYSFUNCTION;

ADOLESCENT; AUTISM SPECTRUM DISORDER; CEREBRAL CORTEX; CHILD; CONNECTOME; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; SENSATION DISORDERS;

EID: 84988843492     PISSN: 08908567     EISSN: 15275418     Source Type: Journal    
DOI: 10.1016/j.jaac.2016.04.013     Document Type: Article

References (44)

1. 1 Monk, C.S., Peltier, S.J., Wiggins, J.L., et al. Abnormalities of intrinsic functional connectivity in autism spectrum disorders. NeuroImage 47 (2009), 764–772.
2. 2 Uddin, L.Q., Supekar, K., Lynch, C.J., et al. Salience network–based classification and prediction of symptom severity in children with autism. JAMA Psychiatry 70 (2013), 869–879.
3. 3 Wass, S., Distortions and disconnections: disrupted brain connectivity in autism. Brain Cogn 75 (2011), 18–28.
4. 4 Greicius, M., Resting-state functional connectivity in neuropsychiatric disorders. Curr Opin Neurol 24 (2008), 424–430.
5. 5 Fox, M.D., Raichle, M.E., Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 8 (2007), 700–711.
6. 6 Fox, M.D., Greicius, M., Clinical applications of resting state functional connectivity. Front Syst Neurosci, 4, 2010, 19.
7. 7 Sridharan, D., Levitin, D.J., Menon, V., A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proc Natl Acad Sci 105 (2008), 12569–12574.
8. 8 Menon, V., Uddin, L.Q., Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct 214 (2010), 655–667.
9. 9 Green, S.A., Rudie, J.D., Colich, N.L., et al. Overreactive brain responses to sensory stimuli in youth with autism spectrum disorders. J Am Acad Child Adolesc Psychiatry 52 (2013), 1158–1172.
10. 10 Green, S.A., Hernandez, L., Tottenham, N., Krasileva, K., Bookheimer, S.Y., Dapretto, M., Neurobiology of sensory overresponsivity in youth with autism spectrum disorders. JAMA Psychiatry 72 (2015), 778–786.
11. 11 Seeley, W.W., Menon, V., Schatzberg, A.F., et al. Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 27 (2007), 2349–2356.
12. 12 Di Martino, A., Ross, K., Uddin, L.Q., Sklar, A.B., Castellanos, F.X., Milham, M.P., Functional brain correlates of social and nonsocial processes in autism spectrum disorders: an activation likelihood estimation meta-analysis. Biol Psychiatry 65 (2009), 63–74.
13. 13 Baranek, G.T., David, F.J., Poe, M.D., Stone, W.L., Watson, L.R., Sensory experience questionnaire: discriminating sensory features in young children with autism, developmental delays, and typical development. J Child Psychol Psychiatry 47 (2006), 591–601.
14. 14 Ben-Sasson, A., Cermak, S.A., Orsmond, G.I., Carter, A.S., Kadlec, M.B., Dunn, W., Extreme sensory modulation behaviors in toddlers with autism. Am J Occup Ther 61 (2007), 584–592.
15. 15 Liss, M., Sensory and attention abnormalities in autistic spectrum disorders. Autism 10 (2006), 155–172.
16. 16 Pfeiffer, B., Kinnealey, M., Reed, C., Herzberg, G., Sensory modulation and affective disorders in children and adolescents with Asperger's disorder. Am J Occup Ther 59 (2005), 335–345.
17. 17 Ben-Sasson, A., Cermak, S.A., Orsmond, G.I., Tager-Flusberg, H., Kadlec, M.B., Carter, A.S., Sensory clusters of toddlers with autism spectrum disorders: differences in affective symptoms. J Child Psychol Psychiatry 49 (2008), 817–825.
18. 18 Zald, D.H., The human amygdala and the emotional evaluation of sensory stimuli. Brain Res Rev 41 (2003), 88–123.
19. 19 Vuilleumier, P., The role of the human amygdala in perception and attention. Whalen, P.J., Phelps, E.A., (eds.) The Human Amygdala, 2009, Guilford Press, New York, 220–249.
20. 20 Adolphs, R., What does the amygdala contribute to social cognition?. Ann N Y Acad Sci 1191 (2010), 42–61.
21. 21 Murphy, E.R., Foss-Feig, J., Kenworthy, L., Gaillard, W.D., Vaidya, C.J., Atypical functional connectivity of the amygdala in childhood autism spectrum disorders during spontaneous attention to eye-gaze. Autism Res Treat, 2012, 2012, 652408.
22. 22 Wechsler, D., Wechsler Abbreviated Scale of Intelligence. 1999, Psychological Corporation, New York.
23. 23 Wechsler, D., Wechsler Intelligence Scale for Children. 4th ed., 2003, Psychological Corporation, San Antonio, TX.
24. 24 Lord, C., Rutter, M., Le Couteur, A., Autism Diagnostic Interview−Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 24 (1994), 659–685.
25. 25 Lord, C., Rutter, M., DiLavore, P., Risi, S., Gotham, K., Bishop, S., Autism Diagnostic Observation Schedule, Second Edition (ADOS-2). 2012, Western Psychological Services, Torrance, CA.
26. 26 Oldfield, R.C., The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 9 (1971), 97–113.
27. 27 Birmaher, B., Khetarpal, S., Brent, D., et al. The Screen for Child Anxiety Related Emotional Disorders (SCARED): scale construction and psychometric characteristics. J Am Acad Child Adolesc Psychiatry 36 (1997), 545–553.
28. 28 Stern, J.A., Gadgil, M.S., Blakeley-Smith, A., Reaven, J.A., Hepburn, S.L., Psychometric properties of the SCARED in youth with autism spectrum disorder. Res Autism Spectr Disord 8 (2014), 1225–1234.
29. 29 van Steensel, F.J.A., Deutschman, A.A.C.G., Bögels, S.M., Examining the Screen for Child Anxiety-Related Emotional Disorder−71 as an assessment tool for anxiety in children with high-functioning autism spectrum disorders. Autism Int J Res Pract 17 (2013), 681–692.
30. 30 Dunn, W., The Sensory Profile: User's Manual. 1999, Psychological Corporation, San Antonio, TX.
31. 31 McIntosh, D.N., Miller, L.J., Evaluation of sensory processing. Dunn, W., (eds.) The Sensory Profile: Examiner's Manual, 1999, Psychological Corporation, San Antonio, TX, 59–73.
32. 32 Schoen, S.A., Miller, L.J., Green, K.E., Pilot study of the Sensory Over-Responsivity Scales: assessment and inventory. Am J Occup Ther 62 (2008), 393–406.
33. 33 Beckmann, C.F., Jenkinson, M., Smith, S.M., General multilevel linear modeling for group analysis in fMRI. NeuroImage 20 (2003), 1052–1063.
34. 34 Woolrich, M., Robust group analysis using outlier inference. NeuroImage 41 (2008), 286–301.
35. 35 Woolrich, M.W., Behrens, T.E.J., Beckmann, C.F., Jenkinson, M., Smith, S.M., Multilevel linear modelling for fMRI group analysis using Bayesian inference. NeuroImage 21 (2004), 1732–1747.
36. 36 Fransson, P., Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. Hum Brain Mapp 26 (2005), 15–29.
37. 37 Patriat, R., Molloy, E.K., Meier, T.B., et al. The effect of resting condition on resting-state fMRI reliability and consistency: a comparison between resting with eyes open, closed, and fixated. NeuroImage 78 (2013), 463–473.
38. 38 Green, S.A., Ben-Sasson, A., Anxiety disorders and sensory over-responsivity in children with autism spectrum disorders: is there a causal relationship?. J Autism Dev Disord 40 (2010), 1495–1504.
39. 39 Schultz, R.T., Grelotti, D.J., Klin, A., et al. The role of the fusiform face area in social cognition: implications for the pathobiology of autism. Philos Trans R Soc B Biol Sci 358 (2003), 415–427.
40. 40 Siegal, M., Varley, R., Neural systems involved in “theory of mind.”. Nat Rev Neurosci 3 (2002), 463–471.
41. 41 Uddin, L.Q., Salience processing and insular cortical function and dysfunction. Nat Rev Neurosci 16 (2015), 55–61.
42. 42 Ben-Sasson, A., Carter, A.S., Briggs-Gowan, M.J., Sensory over-responsivity in elementary school: prevalence and social-emotional correlates. J Abnorm Child Psychol 37 (2009), 705–716.
43. 43 Carter, A.S., Ben-Sasson, A., Briggs-Gowan, M.J., Sensory over-responsivity, psychopathology, and family impairment in school-aged children. J Am Acad Child Adolesc Psychiatry 50 (2011), 1210–1219.
44. 1 Power, J.D., Barnes, K.A., Snyder, A.Z., Schlaggar, B.L., Petersen, S.E., Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. NeuroImage 59 (2012), 2142–2154.