Posttraumatic stress disorder, adverse childhood events, and buccal cell telomere length in elderly swiss former indentured child laborers

Frontiers in Psychiatry

Volumn 7, Issue AUG, 2016, Pages

  Küffer, Andreas Lorenz ^a,b,c   O'Donovan, Aoife ^b,c   Burri, Andrea ^d,e   Maercker, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d AUCKLAND UNIVERSITY OF TECHNOLOGY   (New Zealand)

^e NORTH SHORE HOSPITAL   (New Zealand)

Author keywords

Adverse childhood events; Buccal cell telomere length; Old adults; PTSD; QPCR; Swiss indentured child laborers

Indexed keywords

AGE DISTRIBUTION; AGED; ARTICLE; CHEEK CELL; CHILDHOOD TRAUMA QUESTIONNAIRE; CHILDHOOD TRAUMA SURVIVOR; CONTROLLED STUDY; DEPRESSION; EARLY LIFE STRESS; EDUCATIONAL STATUS; FEMALE; HUMAN; HUMAN CELL; LIFE EVENT; MAJOR CLINICAL STUDY; MALE; MENTAL FUNCTION; PHYSICAL ACTIVITY; POLYMERASE CHAIN REACTION; POSTTRAUMATIC STRESS DISORDER; RISK FACTOR; SEX DIFFERENCE; STRUCTURED CLINICAL INTERVIEW FOR DSM DISORDERS; SWISS; TELOMERE LENGTH;

EID: 84988808517     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2016.00147     Document Type: Article

References (52)

1. Leuenberger M, Seglias L. Versorgt Und Vergessen: Ehemalige Verdingkinder Erzählen. 4th ed. Zurich: Rotpunktverlag (2008).
2. Kuhlman KR, Maercker A, Bachem R, Simmen K, Burri A. Developmental and contextual factors in the role of severe childhood trauma in geriatric depression: the sample case of former indentured child laborers. Child Abuse Negl (2013) 37(11):969-78. doi:10.1016/j.chiabu.2013.04.013
3. Burri A, Maercker A, Krammer S, Simmen-Janevska K. Childhood trauma and PTSD symptoms increase the risk of cognitive impairment in a sample of former indentured child laborers in old age. PLoS One (2013) 8(2):e57826. doi:10.1371/journal.pone.0057826
4. Kendall-Tackett K. Psychological trauma and physical health: a psychoneuroimmunology approach to etiology of negative health effects and possible interventions. Psychol Trauma Theory Res Pract Policy (2009) 1(1):35-48. doi:10.1037/a0015128
5. Blackburn EH. Structure and function of telomeres. Nature (1991) 350(6319):569-73. doi:10.1038/350569a0
6. Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res (1965) 37:614-36. doi:10.1016/0014-4827(65)90211-9
7. von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci (2002) 27(7):339-44. doi:10.1016/S0968-0004(02)02110-2
8. O'Donovan A, Pantell MS, Puterman E, Dhabhar FS, Blackburn EH, Yaffe K, et al. Cumulative inflammatory load is associated with short leukocyte telomere length in the health, aging and body composition study. PLoS One (2011) 6(5):e19687. doi:10.1371/journal.pone.0019687
9. Carroll JE, Diez Roux AV, Fitzpatrick AL, Seeman T. Low social support is associated with shorter leukocyte telomere length in late life: multi-ethnic study of atherosclerosis. Psychosom Med (2013) 75(2):171-7. doi:10.1097/PSY.0b013e31828233bf
10. Herborn KA, Heidinger BJ, Boner W, Noguera JC, Adam A, Daunt F, et al. Stress exposure in early post-natal life reduces telomere length: an experimental demonstration in a long-lived seabird stress exposure in early post-natal life reduces telomere length: an experimental demonstration in a long-lived seabird. Proc R Soc B (2014) 281:e20133151. doi:10.1098/rspb.2013.3151
11. Kotrschal A, Ilmonen P, Penn DJ. Stress impacts telomere dynamics. Biol Lett (2007) 3(2):128-30. doi:10.1098/rsbl.2006.0594
12. Zhang L, Hu X-Z, Benedek DM, Fullerton CS, Forsten RD, Naifeh JA, et al. The interaction between stressful life events and leukocyte telomere length is associated with PTSD. Mol Psychiatry (2013) 19:1-2. doi:10.1038/mp.2013.141
13. O'Donovan A, Epel E, Lin J, Wolkowitz O, Cohen B, Maguen S, et al. Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder. Biol Psychiatry (2011) 70(5):465-71. doi:10.1016/j.biopsych.2011.01.035
14. Shalev I, Moffitt TE, Braithwaite W, Danese A, Fleming NI, Goldman-Mellor S, et al. Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder. Mol Psychiatry (2014) 11:1-8. doi:10.1038/mp.2013.183
15. Drury SS, Mabile E, Brett ZH, Esteves K, Jones E, Shirtcliff E, et al. The association of telomere length with family violence and disruption. Pediatrics (2014) 134(1):e128-37. doi:10.1542/peds.2013-3415
16. Savolainen K, Eriksson JG, Kananen L, Kajantie E, Pesonen A-K, Heinonen K, et al. Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults. Biol Psychol (2014) 97:1-8. doi:10.1016/j.biopsycho.2014.02.002
17. Ladwig K-H, Brockhaus AC, Baumert J, Lukaschek K, Emeny RT, Kruse J, et al. Posttraumatic stress disorder and not depression is associated with shorter leukocyte telomere length: findings from 3, 000 participants in the population-based KORA F4 study. PLoS One (2013) 8(7):e64762. doi:10.1371/journal.pone.0064762
18. Schaakxs R, Wielaard I, Verhoeven JE, Beekman AT, Penninx BW, Comijs HC. Early and recent psychosocial stress and telomere length in. Int Psychogeriatr (2015) 28(3):1-9. doi:10.1017/S1041610215001155
19. Shalev I, Moffitt TE, Sugden K, Williams B, Houts RM, Danese A, et al. Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study. Mol Psychiatry (2012) 18:576-81. doi:10.1038/mp.2012.32
20. Drury SS, Theall K, Gleason MM, Smyke T, De Vivo I, Wong JY, et al. Telomere length and early severe social deprivation: linking early adversity and cellular aging. Mol Psychiatry (2012) 17(7):719-27. doi:10.1038/mp.2011.53
21. Kiecolt-Glaser JK, Gouin J-P, Weng N-P, Malarkey WB, Beversdorf DQ, Glaser R. Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation. Psychosoma Med (2011) 73(1):16-22. doi:10.1097/PSY.0b013e31820573b6
22. Karos K, Niederstrasser N, Abidi L, Bernstein DP, Bader K. Factor structure, reliability, and known groups validity of the German version of the childhood trauma questionnaire (short-form) in Swiss patients and nonpatients. J Child Sex Abus (2014) 23(4):418-30. doi:10.1080/10538712.2014.896840
23. Thombs BD, Bernstein DP, Lobbestael J, Arntz A. A validation study of the Dutch childhood trauma questionnaire-short form: factor structure, reliability, and known-groups validity. Child Abuse Negl (2009) 33(8):518-23. doi:10.1016/j.chiabu.2009.03.001
24. Bernstein DP, Stein JA, Newcomb MD, Walker E, Pogge D, Ahluvalia T, et al. Development and validation of a brief screening version of the childhood trauma questionnaire. Child Abuse Negl (2003) 27(2):169-90. doi:10.1016/S0145-2134(02)00541-0
25. Scher CD, Stein MB, Asmundson GJ, McCreary DR, Forde DR. The childhood trauma questionnaire in a community sample: psychometric properties and normative data. J Trauma Stress (2001) 14(4):843-57. doi:10.1023/A:1013058625719
26. Bernstein D, Fink L. Manual for the Childhood Trauma Questionnaire. New York: The Psychological Corporation (1998).
27. Maercker A, Pielmaier L. Gibt Es Posttraumatische Belastungsstörungen Bei älteren Schweizerinnen Und Schweizern? SANP (2010) 161(2):64-8.
28. Maercker A, Forstmeier S, Wagner B, Glaesmer H, Brähler E. [Post-traumatic stress disorder in Germany. results of a nationwide epidemiological study]. Nervenarzt (2008) 79(5):577-86. doi:10.1007/s00115-008-2467-5
29. Yesavage JA, Sheikh JI. 9/Geriatric depression scale (GDS): recent evidence and development of a shorter version. Clin Gerontol (1986) 5(January):165-73. doi:10.1300/J018v05n01
30. Gauggel S, Birkner B. Validität Und Reliabilität Einer Deutschen Version Der Geriatrischen Depressionsskala (GDS). Z Klin Psychol (1999) 28(1):18-27.
31. Ware J, Kosinski M, Keller SD. A 12-item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care (1996) 34(3):220-33. doi:10.2307/3766749
32. McMichael GL, Gibson CS, O'Callaghan ME, Goldwater PN, Dekker GA, Haan EA, et al. DNA from buccal swabs suitable for high-throughput SNP multiplex analysis. J Biomol Tech (2009) 20:232-5.
33. Freeman B, Smith N, Curtis C, Huckett L, Mill J, Craig IW. DNA from buccal swabs recruited by mail: evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping. Behav Genet (2003) 33(1):67-72. doi:10.1023/A:1021055617738
34. Cell Projects Ltd. DNA stability on isohelix SK1 buccal swabs stored with isohelix dri-capsules is maintained over a 3 + year period. (2011). Available from: http://www.isohelix.com/PDF/isohelix_swab_brochure.pdf
35. O'Callaghan N, Dhillon V, Thomas P, Fenech M. A quantitative real-time PCR method for absolute telomere length. Biotechniques (2008) 44(6):807-9. doi:10.2144/000112761
36. Cawthon RM. Telomere measurement by quantitative PCR. Nucl Acids Res (2002) 30(10):e47. doi:10.1093/nar/30.10.e47
37. Yandell BS. Practical Data Analysis for Designed Experiments. Boca Raton, FL: CRC Press (1997).
38. Aguinis H, Gottfredson RK, Joo H. Best-practice. Org Res Methods (2013) 16(2):270-301. doi:10.1177/1094428112470848
39. Van der Meer T, Te Grotenhuis M, Pelzer B. Influential cases in multilevel modeling: a methodological comment. Am Sociol Rev (2010) 75(1):173-8. doi:10.1177/0003122409359166
40. Royston JP. An extension of Shapiro and Wilk's W test for normality to large samples. Appl Stat (1982) 31(2):115-24. doi:10.2307/2347973
41. R_Core_Team (R Foundation for Statistical Computing). R: A Language and Environment for Statistical Computing. Vienna, Austria (2013). Available from: https://cran.r-project.org/doc/FAQ/R-FAQ.html
42. Boscarino JA. A prospective study of PTSD and early-age heart disease mortality among Vietnam veterans: implications for surveillance and prevention. Psychosom Med (2008) 70(6):668-76. doi:10.1097/PSY.0b013e31817bccaf
43. Boscarino JA. External-cause mortality after psychologic trauma: the effects of stress exposure and predisposition. Compr Psychiatry (2006) 47(6):503-14. doi:10.1016/j.comppsych.2006.02.006
44. McNally RJ, Frueh BC. Why are Iraq and Afghanistan war veterans seeking PTSD disability compensation at unprecedented rates? J Anxiety Disord (2013) 27(5):520-6. doi:10.1016/j.janxdis.2013.07.002
45. Sagi-Schwartz A, Bakermans-Kranenburg MJ, Linn S, Van Ijzendoorn MH. Against all odds: genocidal trauma is associated with longer life-expectancy of the survivors. PLoS One (2013) 8(7):e69179. doi:10.1371/journal.pone.0069179
46. Friedrich U, Griese E, Schwab M, Fritz P, Thon K, Klotz U. Telomere length in different tissues of elderly patients. Mech Ageing Dev (2000) 119(3):89-99. doi:10.1016/S0047-6374(00)00173-1
47. Kimura M, Gazitt Y, Cao X, Zhao X, Lansdorp PM, Aviv A. Synchrony of telomere length among hematopoietic cells. Exp Hematol (2010) 38(10):854-9. doi:10.1016/j.exphem.2010.06.010
48. Nakamura K-I, Izumiyama-Shimomura N, Sawabe M, Arai T, Aoyagi Y, Fujiwara M, et al. Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium. J Invest Dermatol (2002) 119(5):1014-9. doi:10.1046/j.1523-1747.2002.19523.x
49. Okuda K. Telomere length in the newborn. Pediatr Res (2002) 52(3):377-81. doi:10.1203/01.PDR.0000022341.72856.72
50. Thomas P, O'Callaghan NJ, Fenech M. Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease. Mech Ageing Dev (2008) 129(4):183-90. doi:10.1016/j.mad.2007.12.004
51. Youngren K, Jeanclos E, Aviv H, Kimura M, Stock J, Hanna M, et al. Synchrony in telomere length of the human fetus. Hum Genet (1998) 102(6):640-3. doi:10.1007/s004390050755
52. Soneson C, Gerster S, Delorenzi M. Batch effect confounding leads to strong bias in performance estimates obtained by cross-validation. PLoS One (2014) 9(6):e100335. doi:10.1371/journal.pone.0100335