Process evaluation of a point-of-care cluster randomised trial using a computer-delivered intervention to reduce antibiotic prescribing in primary care

BMC Health Services Research

Volumn 14, Issue 1, 2014, Pages

  McDermott, Lisa ^a   Yardley, Lucy ^b   Little, Paul ^b   Van Staa, Tjeerd ^c   Dregan, Alex ^a   McCann, Gerard ^c   Ashworth, Mark ^a   Gulliford, Martin ^a   Charlton, Judith ^a   Rudd, Tony ^a   Wolfe, Charles ^a   Moore, Michael V ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c MEDICINES AND HEALTHCARE PRODUCTS REGULATORY AGENCY   (United Kingdom)

Author keywords

Antibiotic utilisation; Cluster trial; Implementation science; Point of care; Pragmatic trial; Primary care

Indexed keywords

ANTIINFECTIVE AGENT;

ADULT; AGED; COMPARATIVE STUDY; COMPUTER ASSISTED DRUG THERAPY; CONTROLLED STUDY; DECISION SUPPORT SYSTEM; FEMALE; GENERAL PRACTITIONER; HUMAN; MALE; MIDDLE AGED; POINT OF CARE SYSTEM; PREGNANCY; PRESCRIPTION DRUG OVERUSE; PRIMARY HEALTH CARE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTIONS; STANDARDS;

ADULT; AGED; ANTI-BACTERIAL AGENTS; DECISION MAKING, COMPUTER-ASSISTED; DRUG THERAPY, COMPUTER-ASSISTED; FEMALE; GENERAL PRACTITIONERS; HUMANS; MALE; MIDDLE AGED; POINT-OF-CARE SYSTEMS; PREGNANCY; PRESCRIPTION DRUG OVERUSE; PRIMARY HEALTH CARE; RESPIRATORY TRACT INFECTIONS; SURVEYS AND QUESTIONNAIRES;

EID: 84988662492     PISSN: None     EISSN: 14726963     Source Type: Journal    
DOI: 10.1186/s12913-014-0594-1     Document Type: Article

References (34)

1. Grimshaw JM, Eccles MP, Walker AE, Thomas RE: Changing physicians' behavior: what works and thoughts on getting more things to work. J Contin Educ Health Professionals 2002, 2000(22):237-243.
2. Eccles M, McColl E, Steen N, Rousseau N, Grimshaw J, Parkin D, Purves I: Effect of computerised evidence based guidelines on management of asthma and angina in adults in primary care: cluster randomised controlled trial. BMJ 2002, 325:941.
3. MacLean CD, Gagnon M, Callas P, Littenberg B: The Vermont diabetes information system: a cluster randomized trial of a population based decision support system. J Gen Intern Med 2009, 24:1303-1310.
4. Simpson SA, Butler CC, Hood K, Cohen D, Dunstan F, Evans MR, Rollnick S, Moore L, Hare M, Bekkers M, Evans J: Stemming the Tide of Antibiotic Resistance (STAR): a protocol for a trial of a complex intervention addressing the 'why' and 'how' of appropriate antibiotic prescribing in general practice. BMC Fam Pract 2009, 10:20.
5. Hrisos S, Eccles M, Johnston M, Francis J, Kaner EF, Steen N, Grimshaw J: Developing the content of two behavioural interventions: using theory-based interventions to promote GP management of upper respiratory tract infection without prescribing antibiotics #1. BMC Health Serv Res 2008, 8:11.
6. Grimshaw JM, Russell IT: Effect of clinical guidelines on medical practice: a systematic review of rigorous evaluations. Lancet 1993, 342:1317-1322.
7. Shiffman RN, Liaw Y, Brandt CA, Corb GJ: Computer-based guideline implementation systems: a systematic review of functionality and effectiveness. J Am Med Inform Assoc 1999, 6:104-114.
8. Schriger DL, Baraff LJ, Rogers WH, Cretin S: Implementation of clinical guidelines using a computer charting system. Effect on the initial care of health care workers exposed to body fluids. JAMA 1997, 278:1585-1590.
9. Durieux P, Nizard R, Ravaud P, Mounier N, Lepage E: A clinical decision support system for prevention of venous thromboembolism: effect on physician behavior. JAMA 2000, 283:2816-2821.
10. Heselmans A, Van de Velde S, Donceel P, Aertgeerts B, Ramaekers D: Effectiveness of electronic guideline-based implementation systems in ambulatory care settings-a systematic review. Implement Sci 2009, 4:82.
11. Grol R, Grimshaw J: From best evidence to best practice: effective implementation of change in patients' care. Lancet 2003, 362:1225-1230.
12. Davis RL, Wright J, Chalmers F, Levenson L, Brown JC, Lozano P, Christakis DA: A cluster randomized clinical trial to improve prescribing patterns in ambulatory pediatrics. PLoS Clin Trials 2007, 2:e25.
13. Garg AX, Adhikari NK, McDonald H, Rosas-Arellano MP, Devereaux PJ, Beyene J, Sam J, Haynes B: Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. JAMA 2005, 293:1223-1238.
14. Flottorp S, Oxman AD, Havelsrud K, Treweek S, Herrin J: Cluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat. BMJ 2002, 325:367.
15. Roshanov PS, Fernandes N, Wilczynski JM, Hemens BJ, You JJ, Handler SM, Nieuwlaat R, Souza NM, Beyene J, Van Spall HG, Garg AX, Haynes RB: Features of effective computerised clinical decision support systems: meta-regression of 162 randomised trials. BMJ 2013, 346:f6576.
16. McDermott L, Yardley L, Little P, Ashworth M, Gulliford M: Developing a computer-delivered, theory based intervention for guideline implementation in general practice. BMC Fam Pract 2010, 11:90.
17. National Institute for Health and Clinical Excellence: Prescribing of antibiotics for self limiting respiratory tract infections in adults and children in primary care. In National Institute for Health and Clinical Excellence. London: National Insitatute for Health and Care Excellence; 2008.
18. Little P, Dorward M, Warner G, Stephens K, Senior J, Moore M: Importance of patient pressure and perceived pressure and perceived medical need for investigations, referral, and prescribing in primary care: nested observational study. BMJ 2004, 328:444.
19. Dagan R, Leibovitz E, Greenberg D, Yagupsky P, Fliss DM, Leiberman A: Dynamics of pneumococcal nasopharyngeal colonization during the first days of antibiotic treatment in pediatric patients. Pediatr Infect Dis J 1998, 17:880-885.
20. Costelloe C, Metcalfe C, Lovering A, Mant D, Hay AD: Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis. BMJ 2010, 340:c2096.
21. Bandura A: Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev 1977, 84:191-215.
22. Deci EL, Ryan RM: The empirical exploration of intrinsic motivational processes. In Advances in Experimental Social Psychology, Volume 13. Edited by Berkowitz L. New York: Academic press; 1980:39-80.
23. Gulliford MC, van Staa T, McDermott L, Dregan A, McCann G, Ashworth M, Charlton J, Grieve AP, Little P, Moore MV, Yardley L: Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study). Trials 2011, 12:115.
24. Linnan L, Steckler A: Process Evaluation for Public Health Interventions and Research. San Francisico: Jossey-Bass; 2002.
25. Braun V, Clarke V: Using thematic analysis in psychology. Qual Res Psychol 2006, 3:77-101.
26. Field A: Discovering Statistics Using SPSS. London: Sage Publications Limited; 2009.
27. Flottorp S, Havelsrud K, Oxman AD: Process evaluation of a cluster randomized trial of tailored interventions to implement guidelines in primary care - why is it so hard to change practice? Fam Pract 2003, 20:333-339.
28. Grol R, Wensing M: What drives change? Barriers to and incentives for achieving evidence-based practice. Med J Aust 2004, 180:57.
29. Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PAC, Rubin HR: Why don't physicians follow clinical practice guidelines? JAMA 1999, 282:1458-1465.
30. Moxey A, Robertson J, Newby D, Hains I, Williamson M, Pearson SA: Computerized clinical decision support for prescribing: provision does not guarantee uptake. J Am Med Inform Assoc 2010, 17:25-33.
31. Perkins D, Harris M, Tan J, Christl B, Taggart J, Fanaian M: Engaging participants in a complex intervention trial in Australian General Practice. BMC Med Res Methodol 2008, 8:55.
32. Lobo CM, Euser L, Kamp J, Frijling BD, Severens JL, Hulscher MEJL, Grol RP, van der Wouden JC: Process evaluation of a multifaceted intervention to improve cardiovascular disease prevention in general practice. Eur J General Pract 2003, 9:77-83.
33. Michie S, Ashford S, Sniehotta FF, Dombrowski SU, Bishop A, French DP: A refined taxonomy of behaviour change techniques to help people change their physical activity and healthy eating behaviours: The CALO-RE taxonomy. Psychol Health 2011, 26:1479-91498.
34. Abraham C, Michie S: A taxonomy of behaviour change techniques used in interventions. Health Psychol 2008, 27:379-387.