Estimating the immunogenicity of blood group antigens: a modified calculation that corrects for transfusion exposures

British Journal of Haematology

Volumn 175, Issue 1, 2016, Pages 154-160

  Stack, Gary ^a,b   Tormey, Christopher A ^a,b  

^a VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

alloimmunization; blood groups; immunogenicity; immunohematology; transfusion medicine

Indexed keywords

BLOOD GROUP ANTIBODY; BLOOD GROUP ANTIGEN;

ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE COUNT; ERYTHROCYTE TRANSFUSION; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; MALE; POPULATION EXPOSURE; PREVALENCE; PRIORITY JOURNAL;

EID: 84988499961     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.14175     Document Type: Article

References (20)

1. Brecher, M.E. (2005) Technical Manual, 15th edn. AABB Press, Bethesda, MD.
2. Giblett, E.R. (1961) A critique of the theoretical hazard of inter vs. intra-racial transfusion. Transfusion, 1, 233–238.
3. Gunson, H.H., Stratton, F., Cooper, D.G. & Rawlinson, V.I. (1970) Primary immunization of Rh-negative volunteers. British Medical Journal, 1, 593–595.
4. Klein, H.C. & Anstee, D.J. (2014) Mollison's Blood Transfusion in Clinical Medicine, 12th edn. Blackwell Science, Oxford UK.
5. Kornstad, L. & Heisto, H. (1957) The frequency of formation of Kell antibodies in recipients of Kell-positive blood. In: The Proceedings of the 6th Congress of the European Society for Haematology. (ed. by Videbaek, A.A., Neumark, E., Schubothe, H. & Bernard, J.), pp. 754–758. S. Karger, Base, Switzerland.
6. Pollack, W., Ascari, W.Q., Crispen, J.F., O'Connor, R.R. & Ho, T.Y. (1971) Studies on Rh prophylaxis. II. Rh immune prophylaxis after transfusion with Rh-positive blood. Transfusion, 11, 340–344.
7. Redman, M., Regan, F. & Contreras, M. (1996) A prospective study of the incidence of red cell allo-immunisation following transfusion. Vox Sanguinis, 71, 216–220.
8. Schabel, A., König, A.L., Schiebel, M.R. & Sugg, U. (1994) Incidence and persistence of anti-Kell after transfusion of Kell-positive blood. Beitrage zur Infusionstherapie und Transfusionsmedizin, 32, 175–178.
9. Schonewille, H., van de Watering, L.M., Loomans, D.S. & Brand, A. (2006) Red blood cell alloantibodies after transfusion: factors influencing incidence and specificity. Transfusion, 46, 250–256.
10. Spielmann, W. & Seidl, S. (1974) Prevalence of irregular red cell antibodies and their significance in blood transfusion and antenatal care. Vox Sanguinis, 26, 551–559.
11. Tormey, C.A. & Stack, G. (2009a) Immunogenicity of blood group antigens: a mathematical model corrected for antibody evanescence with exclusion of naturally occurring and pregnancy-related antibodies. Blood, 114, 4279–4282.
12. Tormey, C.A. & Stack, G. (2009b) The persistence and evanescence of blood group alloantibodies in men. Transfusion, 49, 505–512.
13. Tormey, C.A. & Stack, G. (2009c) Estimation of combat-related blood group alloimmunization and delayed serologic transfusion reactions in U.S. military veterans. Military Medicine, 174, 503–507.
14. Tormey, C.A., Fisk, J. & Stack, G. (2008) Red blood cell alloantibody frequency, specificity, and properties in a population of male military veterans. Transfusion, 48, 2069–2076.
15. Urbaniak, S.J. (2002) Alloimmunity to human red blood cell antigens. Vox Sanguinis, 83, 293–297.
16. US Census Bureau. (2014) Quick Facts Connecticut. US Census Bureau Washington, DC. Available at: http://quickfacts.census.gov/qfd/states/09000.html. (Accessed 29 January 2016)
17. Vamvakas, E.C. (1996) Epidemiology of red blood cell utilization. Transfusion Medicine Reviews, 10, 44–61.
18. Verduin, E.P., Brand, A., Middleburg, R.A. & Schonewille, H. (2015) Female sex of older patients is an independent risk factor for red blood cell alloimmunization after transfusion. Transfusion, 55, 478–485.
19. Walker, R.H., Lin, D.T. & Hartrick, M.B. (1989) Alloimmunization following blood transfusion. Archives of Pathology & Laboratory Medicine, 113, 254–261.
20. Winters, J.L., Pineda, A.A., Gorden, L.D., Bryant, S.C., Melton, L.J. 3rd, Vamvakas, E.C. & Moore, S.B. (2001) RBC alloantibody specificity and antigen potency in Olmsted County, Minnesota. Transfusion, 41, 1413–1420.