The linear-quadratic approach in clinical practice

Basic Clinical Radiobiology, Fourth Edition

Volumn , Issue , 2009, Pages 120-134

  Joiner, Michael C ^a   Bentzen, Søren M ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84988497079     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/b15450-12     Document Type: Chapter

References (23)

1. Bentzen SM (2006). Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology. Nat Rev Cancer 6: 702-13.
2. Bentzen SM, Dische S (2000). Morbidity related to axillary irradiation in the treatment of breast cancer. Acta Oncol 39: 337-47.
3. Bentzen SM, Overgaard J (1995). Clinical normal-tissue radiobiology. In: Tobias JS, Thomas PR (eds) Current radiation oncology, Vol. 2, London: Arnold, 37-67.
4. Bentzen SM, Ritter MA (2005). The alpha/beta ratio for prostate cancer: what is it, really? Radiother Oncol 76: 1-3.
5. Bentzen SM, Saunders MI, Dische S (1999). Repair halftimes estimated from observations of treatment-related morbidity after CHART or conventional radiotherapy in head and neck cancer. Radiother Oncol 53: 219-26.
6. Bentzen SM, Saunders MI, Dische S, Bond SJ (2001). Radiotherapy-related early morbidity in head and neck cancer: quantitative clinical radiobiology as deduced from the CHART trial. Radiother Oncol 60: 123-35.
7. Bentzen SM, Harari PM, Bernier J (2007). Exploitable mechanisms for combining drugs with radiation:concepts, achievements and future directions. Nat Clin Pract Oncol 4: 172-80.
8. Bentzen SM, Agrawal RK, Aird EG et al. (2008). The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet Oncol 9: 331-41.
9. Brenner DJ, Hall EJ (1999). Fractionation and protraction for radiotherapy of prostate carcinoma. Int J Radiat Oncol Biol Phys 43: 1095-101.
10. Dische S, Saunders MI (1989). Continuous, hyperfractionated, accelerated radiotherapy (CHART): an interim report upon late morbidity. Radiother Oncol 16: 65-72.
11. Fuwa N, Ito Y, Matsumoto A, Morita K (2000). The treatment results of 40 patients with localized endobronchial cancer with external beam irradiation and intraluminal irradiation using low dose rate (192)Ir thin wires with a new catheter. Radiother Oncol 56: 189-95.
12. Guttenberger R, Thames HD, Ang KK (1992). Is the experience with CHART compatible with experimental data? A new model of repair kinetics and computer simulations. Radiother Oncol 25:280-6.
13. Hendry JH, Bentzen SM, Dale RG et al. (1996). A modelled comparison of the effects of using different ways to compensate for missed treatment days in radiotherapy. Clin Oncol 8: 297-307.
14. Joiner MC (2004). A simple alpha/beta-independent method to derive fully isoeffective schedules following changes in dose per fraction. Int J Radiat Oncol Biol Phys 58: 871-5.
15. Kapiteijn E, Marijnen CA, Nagtegaal ID et al. (2001). Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345: 638-46.
16. Lee AW, Sze WM, Fowler JF, Chappell R, Leung SF, Teo P (1999). Caution on the use of altered fractionation for nasopharyngeal carcinoma. Radiother Oncol 52:207-11.
17. Lee SP, Leu MY, Smathers JB, McBride WH, Parker RG, Withers HR (1995). Biologically effective dose distribution based on the linear quadratic model and its clinical relevance. Int J Radiat Oncol Biol Phys 33:375-89.
18. Lukka H, Hayter C, Julian JA et al. (2005). Randomized trial comparing two fractionation schedules for patients with localized prostate cancer. J Clin Oncol 23: 6132-8.
19. Miles EF, Lee WR (2008). Hypofractionation for prostate cancer: a critical review. Semin Radiat Oncol 18:41-7.
20. Overgaard J, Hansen HS, Specht L et al. (2003). Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6 and 7 randomised controlled trial. Lancet 362: 933-40.
21. Thames HD, Bentzen SM, Turesson I, Overgaard M, van den Bogaert W (1990). Time-dose factors in radiotherapy: a review of the human data. Radiother Oncol 19: 219-35.
22. Withers HR, Thames HD, Jr, Peters L J (1983). A new isoeffect curve for change in dose per fraction. Radiother Oncol 1: 187-91.
23. Dale RG, Jones B (ed.) (2007). Radiobiological modeling in radiation oncology. London: British Institute of Radiology.