Fecal microbiota transplant in patients with recurrent Clostridium difficile infection - A retrospective multicenter observational study from the MicroTrans registry;Fäkaler Mikrobiota-Transfer bei rezidivierenden Clostridium-difficile-Infektionen - Eine retrospektive multizentrische Beobachtungsstudie des MicroTrans-Registers

Deutsches Arzteblatt International

Volumn 113, Issue 35-36, 2016, Pages 583-589

  Hagel, Stefan ^a   Stallmach, Andreas ^a   Vehreschild, Maria ^b   Angeli, Wolfgang ^c   Bachmann, Oliver ^c   Gross, Manfred ^c   Jazmati, Nathalie ^c   Heyer, Thomas ^c   Korsten, Friedrich ^c   Kusak, Hasan ^c   Liebhardt, Eva ^c   Matthes, Harald ^c   Merckens, Harald ^c   Missel, Matthias ^c   Reinshagen, Max ^c   Rosien, Ulrich ^c   Schering, Rüdiger ^c   Schmelz, Renate ^c   Tacke, Frank ^c  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b University of Cologne   (Germany)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; DISEASE REGISTRY; FECAL MICROBIOTA TRANSPLANTATION; HUMAN; OBSERVATIONAL STUDY; RECURRENT INFECTION; RETROSPECTIVE STUDY; AGED; CLINICAL TRIAL; CLOSTRIDIUM INFECTION; EPIDEMIOLOGY; FEMALE; GERMANY; MALE; MICROBIOLOGY; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; PREVALENCE; PROCEDURES; RECURRENT DISEASE; REGISTER; RISK FACTOR; SURVIVAL RATE; TREATMENT OUTCOME; UTILIZATION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CLOSTRIDIUM INFECTIONS; FECAL MICROBIOTA TRANSPLANTATION; FEMALE; GERMANY; HUMANS; MALE; MIDDLE AGED; PREVALENCE; RECURRENCE; REGISTRIES; RISK FACTORS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84988450776     PISSN: 18660452     EISSN: None     Source Type: Journal    
DOI: 10.3238/arztebl.2016.0583     Document Type: Article

References (13)

1. Lessa FC, Winston LG, McDonald LC, Emerging Infections Program CdST: Burden of Clostridium difficile infection in the United States. N Engl J Med 2015; 372: 2369-70.
2. Leffler DA, Lamont JT: Clostridium difficile Infection. N Engl J Med 2015; 373: 287-8.
3. Debast SB, Bauer MP, Kuijper EJ: European Society of Clinical Microbiology and Infec tious Diseases: update of the treatment guidance document for Clostridium difficile infection. Clin Microbiol Infect 2014; 20 (Suppl 2): 1-26.
4. Cornely OA, Nathwani D, Ivanescu C, Odufowora-Sita O, Retsa P, Odeyemi IA: Clinical efficacy of fidaxomicin compared with vancomycin and metronidazole in Clostridium difficile infections: a metaanalysis and indirect treatment comparison. J Antimicrob Chemo - ther 2014; 69: 2892-900.
5. van Nood E, Vrieze A, Nieuwdorp M, et al.: Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 2013; 368: 407-15.
6. Youngster I, Russell GH, Pindar C, Ziv-Baran T, Sauk J, Hohmann EL: Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection. JAMA 2014; 312: 1772-8.
7. Agrawal M, Aroniadis OC, Brandt LJ, et al.: The long-term efficacy and safety of fecal microbiota transplant for recurrent, severe, and complicated clostridium difficile infection in 146 elderly individuals. J Clin Gastroenterol 2016; 50: 403-7.
8. Cammarota G, Masucci L, Ianiro G, et al.: Randomised clinical trial: faecal microbiota transplantation by colonoscopy vs. vancomycin for the treatment of recurrent Clostridium difficile infection. Aliment Pharmacol Ther 2015; 41: 835-43.
9. Lee CH, Steiner T, Petrof EO, et al.: Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent clostridium difficile Infection: A randomized clinical trial. JAMA 2016; 315: 142-9.
10. Kleger A, Schnell J, Essig A, et al.: Fecal transplant in refractory Clostridium difficile colitis. Dtsch Arztebl Int 2013; 110: 108-15.
11. Lubbert C, John E, von Muller L: Clostridium difficile infection: guide line-based diagnosis and treatment. Dtsch Arztebl Int 2014; 111: 723-31.
12. Vehreschild JJ, Rüping MJ, Farowski F, Cornely OA: ClinicalSurveys.net-a web-based research portal for rare infectious diseas es. Mycoses 2009; 52: 391.
13. Kelly CR, Ihunnah C, Fischer M, et al.: Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompro - mised patients. Am J Gastroenterol 2014; 109: 1065-71.