Inactivation and identification of three genes encoding glycosyltransferase required for biosynthesis of nogalamycin

Biotechnology and Applied Biochemistry

Volumn 62, Issue 6, 2015, Pages 765-771

  Shao, Lei ^a   Shi, Xuanwen ^a   Liu, Wei ^a   Gao, Xiaorong ^a   Pu, Tian ^a   Ma, Bingji ^b   Wang, Siyuan ^c  

^a SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY   (China)

^b HENAN AGRICULTURAL UNIVERSITY   (China)

^c NANJING NORMAL UNIVERSITY   (China)

Author keywords

biosynthesis; gene disruption; glycosyltransferase (GTs); homologous recombination; nogalamycin

Indexed keywords

ANTIBIOTICS; BIOSYNTHESIS; GENES; GENETIC ENGINEERING; SUGARS;

ANTITUMOR ANTIBIOTICS; BIOSYNTHESIS PATHWAYS; FERMENTATION BROTHS; GENE DISRUPTIONS; GLYCOSYL TRANSFERASE; HOMOLOGOUS RECOMBINATION; NOGALAMYCIN; PRODUCTION YIELD;

BIOCHEMISTRY;

ACLACINOMYCIN; DEOXYSUGAR; GLYCOSYLTRANSFERASE; NOGALAMYCIN; PROTEIN SNOGD; PROTEIN SNOGE; PROTEIN SNOGZ; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; FERMENTATION; GENE DELETION; GENE DISRUPTION; GENE FUNCTION; GENE IDENTIFICATION; GENE INACTIVATION; GENE PRODUCT; GENETIC ENGINEERING; GENOTYPE; GLYCOSYLATION; HOMOLOGOUS RECOMBINATION; NONHUMAN; SEQUENCE ALIGNMENT; BIOSYNTHESIS; DEFICIENCY; ESCHERICHIA COLI; GENE SILENCING; GENETICS; METABOLISM; PROCEDURES; STREPTOMYCES;

ESCHERICHIA COLI; GENE SILENCING; GENETIC ENGINEERING; GLYCOSYLTRANSFERASES; NOGALAMYCIN; SEQUENCE ALIGNMENT; STREPTOMYCES;

EID: 84988299675     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1332     Document Type: Article

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