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Volumn 105, Issue 10, 2016, Pages 3007-3012

Pharmacodynamics and Systems Pharmacology Approaches to Repurposing Drugs in the Wake of Global Health Burden

Author keywords

big data; global health; pharmacodynamics; systems pharmacology

Indexed keywords

DRUG;

EID: 84988038440     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1016/j.xphs.2016.07.004     Document Type: Note
Times cited : (7)

References (33)
  • 1
    • 0023720917 scopus 로고
    • Severe hypertrichosis of the external ear canal during minoxidil therapy
    • 1 Toriumi, D.M., Konior, R.J., Berktold, R.E., Severe hypertrichosis of the external ear canal during minoxidil therapy. Arch Otolaryngol Head Neck Surg 114 (1988), 918–919.
    • (1988) Arch Otolaryngol Head Neck Surg , vol.114 , pp. 918-919
    • Toriumi, D.M.1    Konior, R.J.2    Berktold, R.E.3
  • 2
    • 0030438222 scopus 로고    scopus 로고
    • Sildenafil, a novel effective oral therapy for male erectile dysfunction
    • 2 Boolell, M., Gepi-Attee, S., Gingell, J.C., Allen, M.J., Sildenafil, a novel effective oral therapy for male erectile dysfunction. Br J Urol 78 (1996), 257–261.
    • (1996) Br J Urol , vol.78 , pp. 257-261
    • Boolell, M.1    Gepi-Attee, S.2    Gingell, J.C.3    Allen, M.J.4
  • 3
    • 84988008989 scopus 로고    scopus 로고
    • Available at: Accessed December 21, 2015
    • 3 Global Health Topics: Communicable Diseases, 2015 Available at: http://www.globalhealth.gov/global-health-topics/communicable-diseases/index.html/ Accessed December 21, 2015.
    • (2015) Global Health Topics: Communicable Diseases
  • 4
    • 84986616956 scopus 로고    scopus 로고
    • Health in 2015: From MDGs to SDGs
    • Available at: Accessed January 1, 2016
    • 4 World Health Organization. Health in 2015: From MDGs to SDGs. 2016 Available at: http://www.who.int/gho/publications/mdgs-sdgs/en/ Accessed January 1, 2016.
    • (2016)
  • 5
    • 84987973017 scopus 로고    scopus 로고
    • Drugs@FDA
    • Available at: Accessed January 1, 2016
    • 5 Food and Drug Administration. Drugs@FDA. 2016 Available at: http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm/ Accessed January 1, 2016.
    • (2016)
  • 6
    • 84973376490 scopus 로고    scopus 로고
    • Search Orphan Drug Designations and Approvals
    • Available at: Accessed June 5, 2016
    • 6 Food and Drug Administration. Search Orphan Drug Designations and Approvals. 2016 Available at: http://www.accessdata.fda.gov/scripts/opdlisting/oopd/listResult.cfm Accessed June 5, 2016.
    • (2016)
  • 7
    • 84962393606 scopus 로고    scopus 로고
    • The neglected dimension of global security—a framework for countering infectious-disease crises
    • 7 Sands, P., Mundaca-Shah, C., Dzau, V.J., The neglected dimension of global security—a framework for countering infectious-disease crises. N Engl J Med 374 (2016), 1281–1287.
    • (2016) N Engl J Med , vol.374 , pp. 1281-1287
    • Sands, P.1    Mundaca-Shah, C.2    Dzau, V.J.3
  • 8
    • 84988032903 scopus 로고    scopus 로고
    • 2016. Update: Influenza Activity—Worldwide
    • Available at: Accessed January 1, 2016
    • 8 Centers for Disease Control and Prevention. 2016. Update: Influenza Activity—Worldwide. 1996 Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/00043786.htm/ Accessed January 1, 2016.
    • (1996)
  • 9
    • 68449094325 scopus 로고    scopus 로고
    • The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
    • 9 Currie, C.J., Poole, C.D., Gale, E.A., The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. DiabetologiaI 52 (2009), 1766–1777.
    • (2009) DiabetologiaI , vol.52 , pp. 1766-1777
    • Currie, C.J.1    Poole, C.D.2    Gale, E.A.3
  • 10
    • 80052968453 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus and medications for type 2 diabetes mellitus are associated with risk for and mortality from cancer in a German primary care cohort
    • 10 Baur, D.M., Klotsche, J., Hamnvik, O.P., et al. Type 2 diabetes mellitus and medications for type 2 diabetes mellitus are associated with risk for and mortality from cancer in a German primary care cohort. Metabolism 60 (2011), 1363–1371.
    • (2011) Metabolism , vol.60 , pp. 1363-1371
    • Baur, D.M.1    Klotsche, J.2    Hamnvik, O.P.3
  • 12
    • 84859029647 scopus 로고    scopus 로고
    • Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survival
    • 12 Currie, C.J., Poole, C.D., Jenkins-Jones, S., Gale, E.A., Johnson, J.A., Morgan, C.L., Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survival. Diabetes Care 35 (2012), 299–304.
    • (2012) Diabetes Care , vol.35 , pp. 299-304
    • Currie, C.J.1    Poole, C.D.2    Jenkins-Jones, S.3    Gale, E.A.4    Johnson, J.A.5    Morgan, C.L.6
  • 13
    • 84928658794 scopus 로고    scopus 로고
    • Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality
    • 13 Xu, H., Aldrich, M.C., Chen, Q., et al. Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality. J Am Med Inform Assoc 22 (2015), 179–191.
    • (2015) J Am Med Inform Assoc , vol.22 , pp. 179-191
    • Xu, H.1    Aldrich, M.C.2    Chen, Q.3
  • 14
    • 84907370814 scopus 로고    scopus 로고
    • Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
    • 14 Bridges, H.R., Jones, A.J., Pollak, M.N., Hirst, J., Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria. Biochem J 462 (2014), 475–487.
    • (2014) Biochem J , vol.462 , pp. 475-487
    • Bridges, H.R.1    Jones, A.J.2    Pollak, M.N.3    Hirst, J.4
  • 15
    • 84924869031 scopus 로고    scopus 로고
    • Association between statin use and uveitis: results from the Pacific Ocular Inflammation study
    • 15 Borkar, D.S., Tham, V.M., Shen, E., et al. Association between statin use and uveitis: results from the Pacific Ocular Inflammation study. Am J Ophthalmol 159 (2015), 707–713.
    • (2015) Am J Ophthalmol , vol.159 , pp. 707-713
    • Borkar, D.S.1    Tham, V.M.2    Shen, E.3
  • 16
    • 0037109098 scopus 로고    scopus 로고
    • Simvastatin inhibits inflammatory properties of Staphylococcus aureus alpha-toxin
    • 16 Pruefer, D., Makowski, J., Schnell, M., et al. Simvastatin inhibits inflammatory properties of Staphylococcus aureus alpha-toxin. Circulation 106 (2012), 2104–2110.
    • (2012) Circulation , vol.106 , pp. 2104-2110
    • Pruefer, D.1    Makowski, J.2    Schnell, M.3
  • 17
    • 84860672665 scopus 로고    scopus 로고
    • Statins are associated with reduced use of steroids in inflammatory bowel disease: a retrospective cohort study
    • 17 Crockett, S.D., Hansen, R.A., Sturmer, T., et al. Statins are associated with reduced use of steroids in inflammatory bowel disease: a retrospective cohort study. Inflamm Bowel Dis 18 (2012), 1048–1056.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1048-1056
    • Crockett, S.D.1    Hansen, R.A.2    Sturmer, T.3
  • 18
    • 84954074297 scopus 로고    scopus 로고
    • Effect of artesunate-amodiaquine on mortality related to Ebola virus disease
    • 18 Gignoux, E., Azman, A.S., de Smet, M., et al. Effect of artesunate-amodiaquine on mortality related to Ebola virus disease. N Engl J Med 374 (2016), 23–32.
    • (2016) N Engl J Med , vol.374 , pp. 23-32
    • Gignoux, E.1    Azman, A.S.2    de Smet, M.3
  • 19
    • 84924353789 scopus 로고    scopus 로고
    • Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records
    • 19 Paik, H., Chung, A.Y., Park, H.C., et al. Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records. Sci Rep, 5, 2015, 8580.
    • (2015) Sci Rep , vol.5 , pp. 8580
    • Paik, H.1    Chung, A.Y.2    Park, H.C.3
  • 20
    • 84867338003 scopus 로고    scopus 로고
    • Discovery and preclinical validation of drug indications using compendia of public gene expression data
    • 20 Sirota, M., Dudley, J.T., Kim, J., et al. Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med, 3, 2011, 96ra77.
    • (2011) Sci Transl Med , vol.3 , pp. 96ra77
    • Sirota, M.1    Dudley, J.T.2    Kim, J.3
  • 21
    • 80051831092 scopus 로고    scopus 로고
    • Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease
    • 21 Dudley, J.T., Sirota, M., Shenoy, M., et al. Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease. Sci Transl Med, 3, 2011, 96ra76.
    • (2011) Sci Transl Med , vol.3 , pp. 96ra76
    • Dudley, J.T.1    Sirota, M.2    Shenoy, M.3
  • 22
    • 84903532304 scopus 로고    scopus 로고
    • Topiramate use does not reduce flares of inflammatory bowel disease
    • 22 Crockett, S.D., Schectman, R., Sturmer, T., Kappelman, M.D., Topiramate use does not reduce flares of inflammatory bowel disease. Dig Dis Sci 59 (2014), 1535–1543.
    • (2014) Dig Dis Sci , vol.59 , pp. 1535-1543
    • Crockett, S.D.1    Schectman, R.2    Sturmer, T.3    Kappelman, M.D.4
  • 23
    • 84902498335 scopus 로고    scopus 로고
    • Integrated systems pharmacology analysis of clinical drug-induced peripheral neuropathy
    • 23 Hur, J., Guo, A.Y., Loh, W.Y., Feldman, E.L., Bai, J.P., Integrated systems pharmacology analysis of clinical drug-induced peripheral neuropathy. CPT Pharmacometrics Syst Pharmacol, 3, 2014, e114.
    • (2014) CPT Pharmacometrics Syst Pharmacol , vol.3 , pp. e114
    • Hur, J.1    Guo, A.Y.2    Loh, W.Y.3    Feldman, E.L.4    Bai, J.P.5
  • 24
    • 84938701981 scopus 로고    scopus 로고
    • Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury
    • 24 Melas, I.N., Sakellaropoulos, T., Iorio, F., et al. Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury. Integr Biol (Camb) 7 (2015), 904–920.
    • (2015) Integr Biol (Camb) , vol.7 , pp. 904-920
    • Melas, I.N.1    Sakellaropoulos, T.2    Iorio, F.3
  • 25
    • 84892455642 scopus 로고    scopus 로고
    • Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs
    • 25 Jiang, P., Mukthavaram, R., Chao, Y., et al. Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs. J Transl Med, 12, 2014, 13.
    • (2014) J Transl Med , vol.12 , pp. 13
    • Jiang, P.1    Mukthavaram, R.2    Chao, Y.3
  • 26
    • 84948808461 scopus 로고    scopus 로고
    • Literature review of gastrointestinal physiology in the elderly, in pediatric patients, and in patients with gastrointestinal diseases
    • 26 Bai, J.P., Burckart, G.J., Mulberg, A.E., Literature review of gastrointestinal physiology in the elderly, in pediatric patients, and in patients with gastrointestinal diseases. J Pharm Sci 105 (2016), 476–483.
    • (2016) J Pharm Sci , vol.105 , pp. 476-483
    • Bai, J.P.1    Burckart, G.J.2    Mulberg, A.E.3
  • 27
    • 84973531811 scopus 로고    scopus 로고
    • New role for FDA-approved drugs in combating antibiotic-resistant bacteria
    • 27 Andersson, J.A., Fitts, E.C., Kirtley, M.L., et al. New role for FDA-approved drugs in combating antibiotic-resistant bacteria. Antimicrobial Agents Chemother 60 (2016), 3717–3729.
    • (2016) Antimicrobial Agents Chemother , vol.60 , pp. 3717-3729
    • Andersson, J.A.1    Fitts, E.C.2    Kirtley, M.L.3
  • 28
    • 84937232326 scopus 로고    scopus 로고
    • Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease
    • 28 Kim, C.H., Han, B.S., Moon, J., et al. Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease. Proc Natl Acad Sci U S A 112 (2015), 8756–8761.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 8756-8761
    • Kim, C.H.1    Han, B.S.2    Moon, J.3
  • 29
    • 84937013006 scopus 로고    scopus 로고
    • Lansoprazole is an antituberculous prodrug targeting cytochrome bc1
    • 29 Rybniker, J., Vocat, A., Sala, C., et al. Lansoprazole is an antituberculous prodrug targeting cytochrome bc1. Nat Commun, 6, 2015, 7659.
    • (2015) Nat Commun , vol.6 , pp. 7659
    • Rybniker, J.1    Vocat, A.2    Sala, C.3
  • 30
    • 84927719625 scopus 로고    scopus 로고
    • Infectious disease. Combating emerging viral threats
    • 30 Bekerman, E., Einav, S., Infectious disease. Combating emerging viral threats. Science 348 (2015), 282–283.
    • (2015) Science , vol.348 , pp. 282-283
    • Bekerman, E.1    Einav, S.2
  • 31
    • 84938919218 scopus 로고    scopus 로고
    • Biology of Zika virus infection in human skin cells
    • 31 Hamel, R., Dejarnac, O., Wichit, S., et al. Biology of Zika virus infection in human skin cells. J Virol 89 (2015), 8880–8896.
    • (2015) J Virol , vol.89 , pp. 8880-8896
    • Hamel, R.1    Dejarnac, O.2    Wichit, S.3
  • 33
    • 0034684039 scopus 로고    scopus 로고
    • Expression of the receptor protein-tyrosine kinases Tyro-3, Axl, and mer in the developing rat central nervous system
    • 33 Prieto, A.L., Weber, J.L., Lai, C., Expression of the receptor protein-tyrosine kinases Tyro-3, Axl, and mer in the developing rat central nervous system. J Comp Neurol 425 (2000), 295–314.
    • (2000) J Comp Neurol , vol.425 , pp. 295-314
    • Prieto, A.L.1    Weber, J.L.2    Lai, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.