Surgical prophylaxis with gram-negative activity for reduction of surgical site infections after microvascular reconstruction for head and neck cancer

Head and Neck

Volumn 38, Issue 10, 2016, Pages 1449-1454

  Wagner, Jamie L ^a,b,c   Kenney, Rachel M ^b   Vazquez, Jose A ^d   Ghanem, Tamer A ^b   Davis, Susan L ^b,c  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b HENRY FORD HOSPITAL   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

antibiotics; head and neck cancer; microvascular reconstruction; surgical prophylaxis; surgical site infection

Indexed keywords

BACITRACIN; CEFEPIME; CLINDAMYCIN; POVIDONE IODINE; VANCOMYCIN;

ADULT; ALCOHOL CONSUMPTION; AMERICAN SOCIETY OF ANESTHESIOLOGISTS CLASSIFICATION; ANTIBIOTIC PROPHYLAXIS; ANTIMICROBIAL THERAPY; ARTICLE; BACTERIUM ISOLATE; CANDIDA; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE CLASSIFICATION; ENTEROBACTER; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HEAD AND NECK CANCER; HEAD AND NECK SURGERY; HUMAN; INCIDENCE; INFECTION RISK; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MICROVASCULAR SURGERY; MIDDLE AGED; NEISSERIA; OPERATION DURATION; OUTCOME ASSESSMENT; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; RETROSPECTIVE STUDY; STAPHYLOCOCCUS; STREPTOCOCCUS; SURGICAL INFECTION; WOUND ASSESSMENT;

EID: 84987814190     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.24178     Document Type: Article

References (28)

1. Dor P, Klastersky J. Prophylactic antibiotics in oral, pharyngeal and laryngeal surgery for cancer: a double-blind study. Laryngoscope 1973;83:1992–1998.
2. Becker GD, Parell GJ. Cefazolin prophylaxis in head and neck cancer surgery. Ann Otol Rhinol Laryngol 1979;88(2 Pt 1):183–186.
3. Gerard M, Meunier F, Dor P, et al. Antimicrobial prophylaxis for major head and neck surgery in cancer patients. Antimicrob Agents Chemother 1988;32:1557–1559.
4. Johnson JT, Wagner RL, Schuller DE, Gluckman J, Suen JY, Snyderman NL. Prophylactic antibiotics for head and neck surgery with flap reconstruction. Arch Otolaryngol Head Neck Surg 1992;118:488–490.
5. Phan M, Van der Auwera P, Andry G, et al. Antimicrobial prophylaxis for major head and neck surgery in cancer patients: sulbactam-ampicillin versus clindamycin-amikacin. Antimicrob Agents Chemother 1992;36:2014–2019.
6. Carroll WR, Rosenstiel D, Fix JR, et al. Three-dose vs extended-course clindamycin prophylaxis for free-flap reconstruction of the head and neck. Arch Otolaryngol Head Neck Surg 2003;129:771–774.
7. Penel N, Fournier C, Lefebvre D, Lefebvre JL. Multivariate analysis of risk factors for wound infection in head and neck squamous cell carcinoma surgery with opening of mucosa. Study of 260 surgical procedures. Oral Oncol 2005;41:294–303.
8. Liu SA, Tung KC, Shiao JY, Chiu YT. Preliminary report of associated factors in wound infection after major head and neck neoplasm operations – does the duration of prophylactic antibiotic matter? J Laryngol Otol 2007;122:403–408.
9. Lee DH, Kim SY, Nam SY, Choi SH, Choi JW, Roh JL. Risk factors of surgical site infection in patients undergoing major oncological surgery for head and neck cancer. Oral Oncol 2011;47:528–531.
10. Cunha TF, Soares Melancia TA, Zagalo Fernandes Ribeiro CM, Almeida de Brito JA, Abreu Miguel SS, André Abreu Esteves Bogalhão do Casal D. Risk factors for surgical site infection in cervico-facial oncological surgery. J Craniomaxillofac Surg 2012;40:443–448.
11. Shuman AG, Shuman EK, Hauff SJ, et al. Preoperative topical antimicrobial decolonization in head and neck surgery. Laryngoscope 2012;122:2454–2460.
12. Weber RS, Raad I, Frankenthaler R, et al. Ampicillin-sulbactam vs clindamycin in head and neck oncologic surgery. The need for gram-negative coverage. Arch Otolaryngol Head Neck Surg 1992;118:1159–1163.
13. Righi M, Manfredi R, Farneti G, Pasquini E, Cenacchi V. Short-term versus long-term antimicrobial prophylaxis in oncologic head and neck surgery. Head Neck 1996;18:399–404.
14. Simo R, French G. The use of prophylactic antibiotics in head and neck oncological surgery. Curr Opin Otolaryngol Head Neck Surg 2006;14:55–61.
15. Lotfi CJ, Cavalcanti Rde C, Costa e Silva AM, et al. Risk factors for surgical-site infections in head and neck cancer surgery. Otolaryngol Head Neck Surg 2008;138:74–80.
16. Hirakawa H, Hasegawa Y, Hanai N, Ozawa T, Hyodo I, Suzuki M. Surgical site infection in clean-contaminated head and neck cancer surgery: risk factors and prognosis. Eur Arch Otorhinolaryngol 2013;270:1115–1123.
17. Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm 2013;70:195–283.
18. Ma CY, Ji T, Ow A, et al. Surgical site infection in elderly oral cancer patients: is the evaluation of comorbid conditions helpful in the identification of high-risk ones? J Oral Maxillofac Surg 2012;70:2445–2452.
19. Liu SA, Wong YK, Wang CP, et al. Surgical site infection after preoperative neoadjuvant chemotherapy in patients with locally advanced oral squamous cell carcinoma. Head Neck 2011;33:954–958.
20. Man LX, Beswick DM, Johnson JT. Antibiotic prophylaxis in uncontaminated neck dissection. Laryngoscope 2011;121:1473–1477.
21. American College of Surgeons National Surgical Quality Improvement Program. Chapter 4 – Variables and Definitions. Revised June 24, 2010.
22. NHSN. JulyNHSN Protocol CorrectionsCDC / 2013 CDC/, Clarification and Additions. Revised July 2013.
23. Skitarelić N, Morović M, Manestar D. Antibiotic prophylaxis in clean-contaminated head and neck oncological surgery. J Craniomaxillofac Surg 2007;35:15–20.
24. Chaukar DA, Deshmukh AD, Majeed T, Chaturvedi P, Pai P, D'cruz AK. Factors affecting wound complications in head and neck surgery: a prospective study. Indian J Med Paediatr Oncol 2013;34:247–251.
25. Simons JP, Johnson JT, Yu VL, et al. The role of topical antibiotic prophylaxis in patients undergoing contaminated head and neck surgery with flap reconstruction. Laryngoscope 2001;111:329–335.
26. Russell MD, Goldberg AN. What is the evidence for use of antibiotic prophylaxis in clean-contaminated head and neck surgery? Laryngoscope 2012;122:945–946.
27. Strauss M, Saccogna PW, Allphin AL. Cephazolin and metronidazole prophylaxis in head and neck surgery. J Laryngol Otol 1997;111:631–634.
28. CDC Vital Signs.Centers for Disease Control. Making health care safer: antibiotic Rx in hospitals, proceed with caution. 2014 March. Available at: http://www.cdc.gov/vitalsigns. Accessed March 14, 2014.