메뉴 건너뛰기




Volumn 22, Issue 10, 2016, Pages 1131-1139

The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy

(23)  Wang, Zhihua a,b,c,d   Zhang, Xiao Jing a,b,c   Ji, Yan Xiao a,b,c   Zhang, Peng a,b,c   Deng, Ke Qiong a,b,c   Gong, Jun a,b,c   Ren, Shuxun c   Wang, Xinghua e   Chen, Iris d   Wang, He d   Gao, Chen d   Yokota, Tomohiro d   Ang, Yen Sin f,g   Li, Shen d   Cass, Ashley d,h   Vondriska, Thomas M d   Li, Guangping e   Deb, Arjun d   Srivastava, Deepak f,g   Yang, Huang Tian i,j   more..


Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; LONG NONCODING RNA CHAER; LONG UNTRANSLATED RNA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; POLYCOMB REPRESSIVE COMPLEX 2; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

EID: 84987600948     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4179     Document Type: Article
Times cited : (326)

References (71)
  • 1
    • 84865226993 scopus 로고    scopus 로고
    • Signaling to cardiac hypertrophy: Insights from human and mouse RASopathies
    • Sala, V. et al. Signaling to cardiac hypertrophy: insights from human and mouse RASopathies. Mol. Med. 18, 938-947 (2012).
    • (2012) Mol. Med. , vol.18 , pp. 938-947
    • Sala, V.1
  • 2
    • 84864498547 scopus 로고    scopus 로고
    • Transcriptional regulation of the fetal cardiac gene program
    • Kuwahara, K., Nishikimi, T. & Nakao, K. Transcriptional regulation of the fetal cardiac gene program. J. Pharmacol. Sci. 119, 198-203 (2012).
    • (2012) J. Pharmacol. Sci. , vol.119 , pp. 198-203
    • Kuwahara, K.1    Nishikimi, T.2    Nakao, K.3
  • 3
    • 34548695952 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in heart development and diseases
    • Wang, Y. Mitogen-activated protein kinases in heart development and diseases. Circulation 116, 1413-1423 (2007).
    • (2007) Circulation , vol.116 , pp. 1413-1423
    • Wang, Y.1
  • 4
    • 84872551624 scopus 로고    scopus 로고
    • Hypertrophic cardiomyopathy
    • Maron, B. J. & Maron, M. S. Hypertrophic cardiomyopathy. Lancet 381, 242-255 (2013).
    • (2013) Lancet , vol.381 , pp. 242-255
    • Maron, B.J.1    Maron, M.S.2
  • 6
    • 0030772115 scopus 로고    scopus 로고
    • Functions of mammalian Polycomb group and trithorax group-related genes
    • Gould, A. Functions of mammalian Polycomb group and trithorax group-related genes. Curr. Opin. Genet. Dev. 7, 488-494 (1997).
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 488-494
    • Gould, A.1
  • 7
    • 58049145427 scopus 로고    scopus 로고
    • Genome-wide histone methylation profile for heart failure
    • Kaneda, R. et al. Genome-wide histone methylation profile for heart failure. Genes Cells 14, 69-77 (2009).
    • (2009) Genes Cells , vol.14 , pp. 69-77
    • Kaneda, R.1
  • 8
    • 84907476145 scopus 로고    scopus 로고
    • Epigenetic switch at Atp2a2 and Myh7 gene promoters in pressure-overload-induced heart failure
    • Angrisano, T. et al. Epigenetic switch at Atp2a2 and Myh7 gene promoters in pressure-overload-induced heart failure. PLoS One 9, e106024 (2014).
    • (2014) PLoS One , vol.9 , pp. e106024
    • Angrisano, T.1
  • 9
    • 84890255267 scopus 로고    scopus 로고
    • Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy
    • Papait, R. et al. Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 110, 20164-20169 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 20164-20169
    • Papait, R.1
  • 10
    • 33751277900 scopus 로고    scopus 로고
    • Identification of a novel noncoding RNA, MIAT, that confers risk of myocardial infarction
    • Ishii, N. et al. Identification of a novel noncoding RNA, MIAT, that confers risk of myocardial infarction. J. Hum. Genet. 51, 1087-1099 (2006).
    • (2006) J. Hum. Genet. , vol.51 , pp. 1087-1099
    • Ishii, N.1
  • 11
    • 61849151975 scopus 로고    scopus 로고
    • HBEGF, SRA1 and IK: Three co-segregating genes as determinants of cardiomyopathy
    • Friedrichs, F. et al. HBEGF, SRA1 and IK: Three co-segregating genes as determinants of cardiomyopathy. Genome Res. 19, 395-403 (2009).
    • (2009) Genome Res. , vol.19 , pp. 395-403
    • Friedrichs, F.1
  • 12
    • 78650696753 scopus 로고    scopus 로고
    • Expression of linear and novel circular forms of an INK4/ARF-associated noncoding RNA correlates with atherosclerosis risk
    • Burd, C. E. et al. Expression of linear and novel circular forms of an INK4/ARF-associated noncoding RNA correlates with atherosclerosis risk. PLoS Genet. 6, e1001233 (2010).
    • (2010) PLoS Genet. , vol.6 , pp. e1001233
    • Burd, C.E.1
  • 13
    • 84900844231 scopus 로고    scopus 로고
    • Circulating long noncoding RNA, LIPCAR, predicts survival in patients with heart failure
    • Kumarswamy, R. et al. Circulating long noncoding RNA, LIPCAR, predicts survival in patients with heart failure. Circ. Res. 114, 1569-1575 (2014).
    • (2014) Circ. Res. , vol.114 , pp. 1569-1575
    • Kumarswamy, R.1
  • 14
    • 84899912204 scopus 로고    scopus 로고
    • The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489
    • Wang, K. et al. The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489. Circ. Res. 114, 1377-1388 (2014).
    • (2014) Circ. Res. , vol.114 , pp. 1377-1388
    • Wang, K.1
  • 15
    • 84990177935 scopus 로고    scopus 로고
    • Long noncoding RNA-ROR mediates the reprogramming in cardiac hypertrophy
    • Jiang, F., Zhou, X. & Huang, J. Long noncoding RNA-ROR mediates the reprogramming in cardiac hypertrophy. PLoS One 11, e0152767 (2016).
    • (2016) PLoS One , vol.11 , pp. e0152767
    • Jiang, F.1    Zhou, X.2    Huang, J.3
  • 16
    • 84969234474 scopus 로고    scopus 로고
    • Long noncoding RNA Chast promotes cardiac remodeling
    • Viereck, J. et al. Long noncoding RNA Chast promotes cardiac remodeling. Sci. Transl. Med. 8, 326ra22 (2016).
    • (2016) Sci. Transl. Med. , vol.8 , pp. 326ra22
    • Viereck, J.1
  • 17
    • 85007072223 scopus 로고    scopus 로고
    • The H19 long noncoding RNA is a novel negative regulator of cardiomyocyte hypertrophy
    • Liu, L. et al. The H19 long noncoding RNA is a novel negative regulator of cardiomyocyte hypertrophy. Cardiovasc. Res. 111, 56-65 (2016).
    • (2016) Cardiovasc. Res. , vol.111 , pp. 56-65
    • Liu, L.1
  • 18
    • 84960437336 scopus 로고    scopus 로고
    • Long noncoding RNA Malat-1 is dispensable during pressure-overload-induced cardiac remodeling and failure in mice
    • Peters, T. et al. Long noncoding RNA Malat-1 is dispensable during pressure-overload-induced cardiac remodeling and failure in mice. PLoS One 11, e0150236 (2016).
    • (2016) PLoS One , vol.11 , pp. e0150236
    • Peters, T.1
  • 20
    • 84928233559 scopus 로고    scopus 로고
    • Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long noncoding RNAs
    • Ounzain, S. et al. Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long noncoding RNAs. Eur. Heart J. 36, 353-68a (2015).
    • (2015) Eur. Heart J. , vol.36 , pp. 353a-368a
    • Ounzain, S.1
  • 21
    • 84873829893 scopus 로고    scopus 로고
    • The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
    • Grote, P. et al. The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse. Dev. Cell 24, 206-214 (2013).
    • (2013) Dev. Cell , vol.24 , pp. 206-214
    • Grote, P.1
  • 22
    • 84856083581 scopus 로고    scopus 로고
    • Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts
    • Lee, J. H. et al. Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts. Circ. Res. 109, 1332-1341 (2011).
    • (2011) Circ. Res. , vol.109 , pp. 1332-1341
    • Lee, J.H.1
  • 23
    • 84929359342 scopus 로고    scopus 로고
    • Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development
    • Kurian, L. et al. Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. Circulation 131, 1278-1290 (2015).
    • (2015) Circulation , vol.131 , pp. 1278-1290
    • Kurian, L.1
  • 24
    • 84921942312 scopus 로고    scopus 로고
    • Dawn of the Epi-LncRNAs: New path from Myheart
    • Wang, Z. & Wang, Y. Dawn of the Epi-LncRNAs: new path from Myheart. Circ. Res. 116, 235-236 (2015).
    • (2015) Circ. Res. , vol.116 , pp. 235-236
    • Wang, Z.1    Wang, Y.2
  • 25
    • 84885740857 scopus 로고    scopus 로고
    • Targeted disruption of Hotair leads to homeotic transformation and gene de-repression
    • Li, L. et al. Targeted disruption of Hotair leads to homeotic transformation and gene de-repression. Cell Rep. 5, 3-12 (2013).
    • (2013) Cell Rep. , vol.5 , pp. 3-12
    • Li, L.1
  • 26
    • 84873300214 scopus 로고    scopus 로고
    • Braveheart, a long noncoding RNA required for cardiovascular lineage commitment
    • Klattenhoff, C. A. et al. Braveheart, a long noncoding RNA required for cardiovascular lineage commitment. Cell 152, 570-583 (2013).
    • (2013) Cell , vol.152 , pp. 570-583
    • Klattenhoff, C.A.1
  • 27
    • 79953748673 scopus 로고    scopus 로고
    • A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
    • Wang, K. C. et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 472, 120-124 (2011).
    • (2011) Nature , vol.472 , pp. 120-124
    • Wang, K.C.1
  • 28
    • 84885403598 scopus 로고    scopus 로고
    • The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21WAF1/CIP1 expression
    • Liu, Z. et al. The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21WAF1/CIP1 expression. PLoS One 8, e77293 (2013).
    • (2013) PLoS One , vol.8 , pp. e77293
    • Liu, Z.1
  • 29
    • 81555232542 scopus 로고    scopus 로고
    • Characterization of sucrose transporter alleles and their association with seed-yield-related traits in Brassica napus L
    • Li, F. et al. Characterization of sucrose transporter alleles and their association with seed-yield-related traits in Brassica napus L. BMC Plant Biol. 11, 168 (2011).
    • (2011) BMC Plant Biol. , vol.11 , pp. 168
    • Li, F.1
  • 30
    • 84908020927 scopus 로고    scopus 로고
    • A long noncoding RNA protects the heart from pathological hypertrophy
    • Han, P. et al. A long noncoding RNA protects the heart from pathological hypertrophy. Nature 514, 102-106 (2014).
    • (2014) Nature , vol.514 , pp. 102-106
    • Han, P.1
  • 31
    • 84885374473 scopus 로고    scopus 로고
    • The imprinted H19 lncRNA antagonizes let-7 microRNAs
    • Kallen, A. N. et al. The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol. Cell 52, 101-112 (2013).
    • (2013) Mol. Cell , vol.52 , pp. 101-112
    • Kallen, A.N.1
  • 32
    • 84890828236 scopus 로고    scopus 로고
    • H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1
    • Monnier, P. et al. H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1. Proc. Natl. Acad. Sci. USA 110, 20693-20698 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 20693-20698
    • Monnier, P.1
  • 33
    • 84891782659 scopus 로고    scopus 로고
    • Pfam: The protein families database
    • Finn, R. D. et al. Pfam: The protein families database. Nucleic Acids Res. 42, D222-D230 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. D222-D230
    • Finn, R.D.1
  • 34
    • 80054756754 scopus 로고    scopus 로고
    • Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
    • Chu, C., Qu, K., Zhong, F. L., Artandi, S. E. & Chang, H. Y. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol. Cell 44, 667-678 (2011).
    • (2011) Mol. Cell , vol.44 , pp. 667-678
    • Chu, C.1    Qu, K.2    Zhong, F.L.3    Artandi, S.E.4    Chang, H.Y.5
  • 35
    • 84892981981 scopus 로고    scopus 로고
    • An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins
    • Leppek, K. & Stoecklin, G. An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins. Nucleic Acids Res. 42, e13 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. e13
    • Leppek, K.1    Stoecklin, G.2
  • 36
    • 84891511041 scopus 로고    scopus 로고
    • Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins
    • Wu, L., Murat, P., Matak-Vinkovic, D., Murrell, A. & Balasubramanian, S. Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins. Biochemistry 52, 9519-9527 (2013).
    • (2013) Biochemistry , vol.52 , pp. 9519-9527
    • Wu, L.1    Murat, P.2    Matak-Vinkovic, D.3    Murrell, A.4    Balasubramanian, S.5
  • 37
    • 79956336867 scopus 로고    scopus 로고
    • Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) and c-Jun N-terminal kinase-insulin receptor substrate 1 (JNK-IRS1) pathways
    • Kang, S., Chemaly, E. R., Hajjar, R. J. & Lebeche, D. Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) and c-Jun N-terminal kinase-insulin receptor substrate 1 (JNK-IRS1) pathways. J. Biol. Chem. 286, 18465-18473 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 18465-18473
    • Kang, S.1    Chemaly, E.R.2    Hajjar, R.J.3    Lebeche, D.4
  • 38
    • 45849105156 scopus 로고    scopus 로고
    • The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
    • Sancak, Y. et al. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320, 1496-1501 (2008).
    • (2008) Science , vol.320 , pp. 1496-1501
    • Sancak, Y.1
  • 39
    • 0037178786 scopus 로고    scopus 로고
    • MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
    • Kim, D. H. et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110, 163-175 (2002).
    • (2002) Cell , vol.110 , pp. 163-175
    • Kim, D.H.1
  • 40
    • 3342895823 scopus 로고    scopus 로고
    • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
    • Sarbassov, D. D. et al. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14, 1296-1302 (2004).
    • (2004) Curr. Biol. , vol.14 , pp. 1296-1302
    • Sarbassov, D.D.1
  • 41
    • 84921364521 scopus 로고    scopus 로고
    • Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1-NO
    • Li, Q., Wang, P., Ye, K. & Cai, H. Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1-NO. Proc. Natl. Acad. Sci. USA 112, 899-904 (2015).
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 899-904
    • Li, Q.1    Wang, P.2    Ye, K.3    Cai, H.4
  • 42
    • 80052978224 scopus 로고    scopus 로고
    • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
    • Cabili, M. N. et al. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 25, 1915-1927 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 1915-1927
    • Cabili, M.N.1
  • 43
    • 84862777974 scopus 로고    scopus 로고
    • Epigenetic repression of cardiac progenitor gene expression by EZH2 is required for postnatal cardiac homeostasis
    • Delgado-Olguín, P. et al. Epigenetic repression of cardiac progenitor gene expression by EZH2 is required for postnatal cardiac homeostasis. Nat. Genet. 44, 343-347 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 343-347
    • Delgado-Olguín, P.1
  • 44
    • 84880045471 scopus 로고    scopus 로고
    • MicroRNA-214 provokes cardiac hypertrophy via repression of EZH2
    • Yang, T. et al. MicroRNA-214 provokes cardiac hypertrophy via repression of EZH2. Biochem. Biophys. Res. Commun. 436, 578-584 (2013).
    • (2013) Biochem. Biophys. Res. Commun. , vol.436 , pp. 578-584
    • Yang, T.1
  • 45
    • 79956291600 scopus 로고    scopus 로고
    • Histone demethylase JMJD2B coordinates H3K4 and H3K9 methylation and promotes hormonally responsive breast carcinogenesis
    • Shi, L. et al. Histone demethylase JMJD2B coordinates H3K4 and H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc. Natl. Acad. Sci. USA 108, 7541-7546 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 7541-7546
    • Shi, L.1
  • 46
    • 35148867907 scopus 로고    scopus 로고
    • UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
    • Agger, K. et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449, 731-734 (2007).
    • (2007) Nature , vol.449 , pp. 731-734
    • Agger, K.1
  • 47
    • 78649668307 scopus 로고    scopus 로고
    • MTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy
    • Song, X. et al. mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy. Am. J. Physiol. Cell Physiol. 299, C1256-C1266 (2010).
    • (2010) Am. J. Physiol. Cell Physiol. , vol.299 , pp. C1256-C1266
    • Song, X.1
  • 48
    • 84930934938 scopus 로고    scopus 로고
    • The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload
    • Liu, X., Wang, X., Bi, Y., Bu, P. & Zhang, M. The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload. Exp. Cell Res. 335, 123-134 (2015).
    • (2015) Exp. Cell Res. , vol.335 , pp. 123-134
    • Liu, X.1    Wang, X.2    Bi, Y.3    Bu, P.4    Zhang, M.5
  • 49
    • 84924544203 scopus 로고    scopus 로고
    • The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signaling and leads to chronic heart failure
    • Xu, N. et al. The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signaling and leads to chronic heart failure. J. Pathol. 235, 672-685 (2015).
    • (2015) J. Pathol. , vol.235 , pp. 672-685
    • Xu, N.1
  • 50
    • 84905014655 scopus 로고    scopus 로고
    • AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1
    • Li, Y. et al. AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1. Arch. Biochem. Biophys. 558, 79-86 (2014).
    • (2014) Arch. Biochem. Biophys. , vol.558 , pp. 79-86
    • Li, Y.1
  • 51
    • 84959900835 scopus 로고    scopus 로고
    • Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy
    • Shende, P. et al. Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. Cardiovasc. Res. 109, 103-114 (2016).
    • (2016) Cardiovasc. Res. , vol.109 , pp. 103-114
    • Shende, P.1
  • 52
    • 79953033875 scopus 로고    scopus 로고
    • Cardiac Raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression and causes heart failure in mice
    • Shende, P. et al. Cardiac Raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression and causes heart failure in mice. Circulation 123, 1073-1082 (2011).
    • (2011) Circulation , vol.123 , pp. 1073-1082
    • Shende, P.1
  • 53
    • 78649807567 scopus 로고    scopus 로고
    • Phosphorylation of the PRC2 component EZH2 is cell-cycle-regulated and upregulates its binding to ncRNA
    • Kaneko, S. et al. Phosphorylation of the PRC2 component EZH2 is cell-cycle-regulated and upregulates its binding to ncRNA. Genes Dev. 24, 2615-2620 (2010).
    • (2010) Genes Dev. , vol.24 , pp. 2615-2620
    • Kaneko, S.1
  • 54
    • 84954542873 scopus 로고    scopus 로고
    • Pathological left ventricular hypertrophy and stem cells: Current evidence and new perspectives
    • Marketou, M. E., Parthenakis, F. & Vardas, P. E. Pathological left ventricular hypertrophy and stem cells: current evidence and new perspectives. Stem Cells Int. 2016, 5720758 (2016).
    • (2016) Stem Cells Int. , vol.2016 , pp. 5720758
    • Marketou, M.E.1    Parthenakis, F.2    Vardas, P.E.3
  • 55
    • 84990035026 scopus 로고    scopus 로고
    • National Research Council. 8th edn. The National Academies Press
    • National Research Council. Guide for the Care and Use of Laboratory Animals 8th edn. (The National Academies Press, 2011).
    • (2011) Guide for the Care and Use of Laboratory Animals
  • 56
    • 0034460363 scopus 로고    scopus 로고
    • A novel Rb-and p300-binding protein inhibits transactivation by MyoD
    • MacLellan, W. R., Xiao, G., Abdellatif, M. & Schneider, M. D. A novel Rb-and p300-binding protein inhibits transactivation by MyoD. Mol. Cell. Biol. 20, 8903-8915 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8903-8915
    • MacLellan, W.R.1    Xiao, G.2    Abdellatif, M.3    Schneider, M.D.4
  • 57
    • 77956623148 scopus 로고    scopus 로고
    • Reporter-based isolation of induced pluripotent stem cell-and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance
    • van Laake, L. W. et al. Reporter-based isolation of induced pluripotent stem cell-and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circ. Res. 107, 340-347 (2010).
    • (2010) Circ. Res. , vol.107 , pp. 340-347
    • Van Laake, L.W.1
  • 58
    • 84908403146 scopus 로고    scopus 로고
    • Mesenchymal-endothelial transition contributes to cardiac neovascularization
    • Ubil, E. et al. Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature 514, 585-590 (2014).
    • (2014) Nature , vol.514 , pp. 585-590
    • Ubil, E.1
  • 59
    • 0033853519 scopus 로고    scopus 로고
    • Culture and adenoviral infection of adult mouse cardiac myocytes: Methods for cellular genetic physiology
    • Zhou, Y. Y. et al. Culture and adenoviral infection of adult mouse cardiac myocytes: methods for cellular genetic physiology. Am. J. Physiol. Heart Circ. Physiol. 279, H429-H436 (2000).
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.279 , pp. H429-H436
    • Zhou, Y.Y.1
  • 60
    • 84877707375 scopus 로고    scopus 로고
    • One-step generation of mice carrying mutations in multiple genes by CRISPR-Cas-mediated genome engineering
    • Wang, H. et al. One-step generation of mice carrying mutations in multiple genes by CRISPR-Cas-mediated genome engineering. Cell 153, 910-918 (2013).
    • (2013) Cell , vol.153 , pp. 910-918
    • Wang, H.1
  • 61
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • Langmead, B. & Salzberg, S. L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357-359 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 62
    • 84862630475 scopus 로고    scopus 로고
    • NetWalker: A contextual network analysis tool for functional genomics
    • Komurov, K., Dursun, S., Erdin, S. & Ram, P. T. NetWalker: A contextual network analysis tool for functional genomics. BMC Genomics 13, 282 (2012).
    • (2012) BMC Genomics , vol.13 , pp. 282
    • Komurov, K.1    Dursun, S.2    Erdin, S.3    Ram, P.T.4
  • 63
    • 67651005823 scopus 로고    scopus 로고
    • Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells
    • Lu, G. et al. Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells. J. Clin. Invest. 119, 1678-1687 (2009).
    • (2009) J. Clin. Invest. , vol.119 , pp. 1678-1687
    • Lu, G.1
  • 64
    • 17644410781 scopus 로고    scopus 로고
    • Nucleosome-binding and histone methyltransferase activity of Drosophila PRC2
    • Nekrasov, M., Wild, B. & Müller, J. Nucleosome-binding and histone methyltransferase activity of Drosophila PRC2. EMBO Rep. 6, 348-353 (2005).
    • (2005) EMBO Rep. , vol.6 , pp. 348-353
    • Nekrasov, M.1    Wild, B.2    Müller, J.3
  • 65
    • 42949149690 scopus 로고    scopus 로고
    • Advances in RIP-chip analysis: RNA-binding protein immunoprecipitation-microarray profiling
    • Baroni, T. E., Chittur, S. V., George, A. D. & Tenenbaum, S. A. Advances in RIP-chip analysis: RNA-binding protein immunoprecipitation-microarray profiling. Methods Mol. Biol. 419, 93-108 (2008).
    • (2008) Methods Mol. Biol. , vol.419 , pp. 93-108
    • Baroni, T.E.1    Chittur, S.V.2    George, A.D.3    Tenenbaum, S.A.4
  • 66
    • 84892981981 scopus 로고    scopus 로고
    • An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins
    • Leppek, K. & Stoecklin, G. An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins. Nucleic Acids Res. 42, e13 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. e13
    • Leppek, K.1    Stoecklin, G.2
  • 67
    • 80052586181 scopus 로고    scopus 로고
    • Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes
    • Sdek, P. et al. Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes. J. Cell Biol. 194, 407-423 (2011).
    • (2011) J. Cell Biol. , vol.194 , pp. 407-423
    • Sdek, P.1
  • 68
    • 80053217575 scopus 로고    scopus 로고
    • ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity
    • Young, M. D. et al. ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity. Nucleic Acids Res. 39, 7415-7427 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. 7415-7427
    • Young, M.D.1
  • 69
    • 77953361032 scopus 로고    scopus 로고
    • Compensatory hypertrophy induced by ventricular-cardiomyocyte-specific COX-2 expression in mice
    • Streicher, J. M., Kamei, K., Ishikawa, T. O., Herschman, H. & Wang, Y. Compensatory hypertrophy induced by ventricular-cardiomyocyte-specific COX-2 expression in mice. J. Mol. Cell. Cardiol. 49, 88-94 (2010).
    • (2010) J. Mol. Cell. Cardiol. , vol.49 , pp. 88-94
    • Streicher, J.M.1    Kamei, K.2    Ishikawa, T.O.3    Herschman, H.4    Wang, Y.5
  • 70
    • 58149385416 scopus 로고    scopus 로고
    • Loss of Bmx nonreceptor tyrosine kinase prevents pressure-overload-induced cardiac hypertrophy
    • Mitchell-Jordan, S. A. et al. Loss of Bmx nonreceptor tyrosine kinase prevents pressure-overload-induced cardiac hypertrophy. Circ. Res. 103, 1359-1362 (2008).
    • (2008) Circ. Res. , vol.103 , pp. 1359-1362
    • Mitchell-Jordan, S.A.1
  • 71
    • 84897045727 scopus 로고    scopus 로고
    • Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy
    • Jiang, D. S. et al. Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy. Hypertension 63, 713-722 (2014).
    • (2014) Hypertension , vol.63 , pp. 713-722
    • Jiang, D.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.