메뉴 건너뛰기




Volumn 134, Issue , 2016, Pages 58-62

Brincidofovir (CMX-001) for refractory and resistant CMV and HSV infections in immunocompromised cancer patients: A single-center experience

Author keywords

Brincidofovir; Cancer; Cytomegalovirus; Herpes simplex virus; Resistance

Indexed keywords

ACICLOVIR; BRINCIDOFOVIR; CIDOFOVIR; CORTICOSTEROID; FOSCARNET; GANCICLOVIR; IMIQUIMOD; IMMUNOGLOBULIN; MYCOPHENOLATE MOFETIL; NEW DRUG; VALACICLOVIR; VALGANCICLOVIR; ANTIVIRUS AGENT; CYTOSINE; PHOSPHONIC ACID DERIVATIVE;

EID: 84986328593     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2016.08.024     Document Type: Article
Times cited : (31)

References (12)
  • 1
    • 0035991718 scopus 로고    scopus 로고
    • Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro
    • Beadle, J.R., Hartline, C., Aldern, K.A., et al. Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro. Antimicrob. Agents Chemother. 46 (2002), 2381–2386.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 2381-2386
    • Beadle, J.R.1    Hartline, C.2    Aldern, K.A.3
  • 2
    • 67651085554 scopus 로고    scopus 로고
    • How we treat cytomegalovirus in hematopoietic cell transplant recipients
    • Boeckh, M., Ljungman, P., How we treat cytomegalovirus in hematopoietic cell transplant recipients. Blood 113 (2009), 5711–5719.
    • (2009) Blood , vol.113 , pp. 5711-5719
    • Boeckh, M.1    Ljungman, P.2
  • 3
    • 84986331970 scopus 로고    scopus 로고
    • Chimerix Announces Top-Line Results From Phase 3 SUPPRESS Trial of Brincidofovir
    • (accessed 01.04.16)
    • Chimerix Press Release, Chimerix Announces Top-Line Results From Phase 3 SUPPRESS Trial of Brincidofovir. 2015 http://ir.chimerix.com/releasedetail.cfm?releaseid=948172 (accessed 01.04.16).
    • (2015)
    • Chimerix Press Release1
  • 4
    • 0032890689 scopus 로고    scopus 로고
    • Resistance of human cytomegalovirus to antiviral drugs
    • Erice, A., Resistance of human cytomegalovirus to antiviral drugs. Clin. Microbiol. Rev. 12 (1999), 286–297.
    • (1999) Clin. Microbiol. Rev. , vol.12 , pp. 286-297
    • Erice, A.1
  • 5
    • 84907059423 scopus 로고    scopus 로고
    • Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses
    • Florescu, D.F., Keck, M.A., Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses. Expert Rev. Anti Infect. Ther. 12 (2014), 1171–1178.
    • (2014) Expert Rev. Anti Infect. Ther. , vol.12 , pp. 1171-1178
    • Florescu, D.F.1    Keck, M.A.2
  • 6
    • 14744270979 scopus 로고    scopus 로고
    • Human cytomegalovirus resistance to antiviral drugs
    • Gilbert, C., Boivin, G., Human cytomegalovirus resistance to antiviral drugs. Antimicrob. Agents Chemother. 49 (2005), 873–883.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 873-883
    • Gilbert, C.1    Boivin, G.2
  • 7
    • 67349157073 scopus 로고    scopus 로고
    • Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art
    • Hostetler, K.Y., Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art. Antivir. Res. 82 (2009), A84–A98.
    • (2009) Antivir. Res. , vol.82 , pp. A84-A98
    • Hostetler, K.Y.1
  • 8
    • 7444256060 scopus 로고    scopus 로고
    • Resistance of herpes simplex virus infections to nucleoside analogues in HIV-infected patients
    • Levin, M.J., Bacon, T.H., Leary, J.J., Resistance of herpes simplex virus infections to nucleoside analogues in HIV-infected patients. Clin. Infect. Dis. 39:Suppl. 5 (2004), S248–S257.
    • (2004) Clin. Infect. Dis. , vol.39 , pp. S248-S257
    • Levin, M.J.1    Bacon, T.H.2    Leary, J.J.3
  • 9
    • 84884528238 scopus 로고    scopus 로고
    • CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation
    • Marty, F.M., Winston, D.J., Rowley, S.D., et al. CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation. N. Engl. J. Med. 369 (2013), 1227–1236.
    • (2013) N. Engl. J. Med. , vol.369 , pp. 1227-1236
    • Marty, F.M.1    Winston, D.J.2    Rowley, S.D.3
  • 11
    • 78349234678 scopus 로고    scopus 로고
    • Efficacy of CMX001 against herpes simplex virus infections in mice and correlations with drug distribution studies
    • Quenelle, D.C., Lampert, B., Collins, D.J., Rice, T.L., Painter, G.R., Kern, E.R., Efficacy of CMX001 against herpes simplex virus infections in mice and correlations with drug distribution studies. J. Infect. Dis. 202 (2010), 1492–1499.
    • (2010) J. Infect. Dis. , vol.202 , pp. 1492-1499
    • Quenelle, D.C.1    Lampert, B.2    Collins, D.J.3    Rice, T.L.4    Painter, G.R.5    Kern, E.R.6
  • 12
    • 24144458260 scopus 로고    scopus 로고
    • Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro
    • Williams-Aziz, S.L., Hartline, C.B., Harden, E.A., et al. Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro. Antimicrob. Agents Chemother. 49 (2005), 3724–3733.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 3724-3733
    • Williams-Aziz, S.L.1    Hartline, C.B.2    Harden, E.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.