Population Pharmacokinetics and Exposure–Response (Efficacy and Safety/Tolerability) of Empagliflozin in Patients with Type 2 Diabetes

Diabetes Therapy

Volumn 7, Issue 3, 2016, Pages 455-471

  Baron, Kyle T ^a   Macha, Sreeraj ^b   Broedl, Uli C ^c   Nock, Valerie ^c   Retlich, Silke ^c   Riggs, Matthew ^a  

^a Metrum Research Group   (United States)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Efficacy; Empagliflozin; Exposure response; Pharmacometrics; Population pharmacokinetics; Tolerability; Type 2 diabetes mellitus

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; EMPAGLIFLOZIN; LACTATE DEHYDROGENASE;

ADULT; ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HYPOGLYCEMIA; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SIMULATION;

EID: 84986192887     PISSN: 18696953     EISSN: 18696961     Source Type: Journal    
DOI: 10.1007/s13300-016-0174-y     Document Type: Article

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