Onco-lncRNA HOTAIR and its functional genetic variants in papillary thyroid carcinoma

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Zhu, Hui ^a   Lv, Zheng ^b   An, Changming ^c   Shi, Meng ^d   Pan, Wenting ^d   Zhou, Liqing ^e   Yang, Wenjun ^f   Yang, Ming ^a  

^a SHANDONG CANCER HOSPITAL AND INSTITUTE   (China)

^b THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^c CANCER HOSPITAL   (China)

^d BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^e Huaian No 2 Hospital   (China)

^f NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HOTAIR LONG UNTRANSLATED RNA, HUMAN; LONG UNTRANSLATED RNA;

ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDY; GENETICS; HUMAN; MALE; PAPILLARY CARCINOMA; SEX FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; THYROID TUMOR; TUMOR CELL LINE; UPREGULATION;

ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA, PAPILLARY; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC ASSOCIATION STUDIES; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, LONG NONCODING; SEX FACTORS; THYROID NEOPLASMS; UP-REGULATION;

EID: 84984656684     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep31969     Document Type: Article

References (24)

1. Chen, W., et al. Annual report on status of cancer in China, 2011. Chin J Cancer Res 27, 2-12 (2015).
2. Schneider, A. B. & Sarne, D. H. Long-term risks for thyroid cancer and other neoplasms after exposure to radiation. Nat Clin Pract Endocrinol Metab 1, 82-91 (2005).
3. Goldgar, D. E., Easton, D. F., Cannon-Albright, L. A. & Skolnick, M. H. Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands. J Natl Cancer Inst 86, 1600-1608 (1994).
4. Liz, J. & Esteller, M. lncRNAs and microRNAs with a role in cancer development. Biochim Biophys Acta 1859, 169-176 (2016).
5. Gupta, R. A., et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 464, 1071-1076 (2010).
6. Kogo, R., et al. Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res 71, 6320-6326 (2011).
7. Niinuma, T., et al. Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors. Cancer Res 72, 1126-1136 (2012).
8. Kim, K., et al. HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene 32, 1616-1625 (2013).
9. Li, Y., et al. HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc. Cancer Res 76, 293-304 (2016).
10. Zhang, A., et al. LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration- Resistant Prostate Cancer. Cell Rep 13, 209-221 (2015).
11. Pastori, C., et al. The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation. Proc Natl Acad Sci USA 112, 8326-8331 (2015).
12. Zhang, X., et al. The identification of an ESCC susceptibility SNP rs920778 that regulates the expression of lncRNA HOTAIR via a novel intronic enhancer. Carcinogenesis 35, 2062-2067 (2014).
13. Pan, W., et al. A functional lncRNA HOTAIR genetic variant contributes to gastric cancer susceptibility. Mol Carcinog 55, 90-96 (2016).
14. Ge, Y., et al. fMiRNA-192 and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma. PLoS Genet 11, e1005726 (2015).
15. Wang, X., et al. Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits proliferation, migration, and invasion of esophageal squamous cell carcinoma cells. J Biol Chem 290, 3925-3935 (2015).
16. Yoon, H., et al. Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest. Int J Cancer 121, 767-775 (2007).
17. Jendrzejewski, J., et al. The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type. Proc Natl Acad Sci USA 109, 8646-8651 (2012).
18. Jendrzejewski, J., et al. PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression. J Clin Endocrinol Metab 100, E1370-1377 (2015).
19. He, H., et al. Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2. J Clin Endocrinol Metab 100, E164-172 (2015).
20. Pan, W., et al. Whole exome sequencing identifies lncRNA GAS8-AS1 and LPAR4 as novel papillary thyroid carcinoma driver alternations. Hum Mol Genet 25, 1875-1884 (2016).
21. Jeong, S., et al. Relationship of Focally Amplified Long Noncoding on Chromosome 1 (FAL1) lncRNA with E2F Transcription Factors in Thyroid Cancer. Medicine (Baltimore) 95, e2592 (2016).
22. Liu, L., et al. Long noncoding RNA H19 competitively binds miR-17-5p to regulate YES1 expression in thyroid cancer. FEBS J 283, 2326-2339 (2016).
23. Kim. D., et al. Upregulation of long noncoding RNA LOC100507661 promotes tumor aggressiveness in thyroid cancer. Mol Cell Endocrinol S0303-7207, 30150-30152 (2016).
24. Xu, B., et al. The Long Non-Coding RNA ENST00000537266 and ENST00000426615 Influence Papillary Thyroid Cancer Cell Proliferation and Motility. Cell Physiol Biochem 38, 368-378 (2016).