Ocular blood flow in glaucoma – the Leuven Eye Study

Acta Ophthalmologica

Volumn 94, Issue 6, 2016, Pages 592-598

  Abegão Pinto, Luís ^a,b   Willekens, Koen ^a   Van Keer, Karel ^a   Shibesh, Abraham ^c   Molenberghs, Geert ^c,d   Vandewalle, Evelien ^a   Stalmans, Ingeborg ^a,e  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^c KU LEUVEN   (Belgium)

^d HASSELT UNIVERSITY   (Belgium)

^e UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

colour Doppler imaging; normal tension glaucoma; ocular blood flow; primary open angle glaucoma; retinal oximetry

Indexed keywords

AGE; AGED; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL PARAMETERS; CHOROID; CHOROIDAL THICKNESS; CLINICAL ASSESSMENT TOOL; COLOR DOPPLER FLOWMETRY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE CLASSIFICATION; EYE BLOOD FLOW; FEMALE; GENDER; GLAUCOMA; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; LOW TENSION GLAUCOMA; MAJOR CLINICAL STUDY; MALE; OCULAR BLOOD VESSEL; OCULOPLETHYSMOGRAPHY; OPEN ANGLE GLAUCOMA; OPTICAL COHERENCE TOMOGRAPHY; OXIMETRY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RETINAL OXIMETRY; RETINAL VENOUS SATURATION; RETROBULBAR VESSEL; SCREENING; VISUAL SYSTEM EXAMINATION;

EID: 84984645406     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/aos.12962     Document Type: Article

References (40)

1. Abegão Pinto L, Vandewalle E, Willekens K, Marques-Neves C & Stalmans I (2014): Ocular pulse amplitude and Doppler waveform analysis in glaucoma patients. Acta Ophthalmol 92: e280–e285.
2. Abegão Pinto L, Vandewalle E, De Clerck E, Marques-Neves C & Stalmans I (2012): Ophthalmic artery Doppler waveform changes associated with increased damage in glaucoma patients. Invest Ophthalmol Vis Sci 53: 2448–2453.
3. Bonomi L, Marchini G, Marraffa M, Bernardi P, De Franco I, Perfetti S, Varotto A & Tenna V (1998): Prevalence of glaucoma and intraocular pressure distribution in a defined population. The Egna-Neumarkt Study. Ophthalmology 105: 209–215.
4. Broadway DC & Drance SM (1998): Glaucoma and vasospasm. Br J Ophthalmol 82: 862–870.
5. Cherecheanu AP, Garhofer G, Schmidl D, Werkmeister R & Schmetterer L (2013): Ocular perfusion pressure and ocular blood flow in glaucoma. Curr Opin Pharmacol 13: 36–42.
6. Costa VP, Harris A, Anderson D et al. (2014): Ocular perfusion pressure in glaucoma. Acta Ophthalmol 92: e252–e266.
7. Cursiefen C, Wisse M, Cursiefen S, Junemann A, Martus P & Korth M (2000): Migraine and tension headache in high-pressure and normal-pressure glaucoma. Am J Ophthalmol 129: 102–104.
8. Dziura JD, Post LA, Zhao Q, Fu Z & Peduzzi P (2013): Strategies for dealing with missing data in clinical trials: from design to analysis. Yale J Biol Med 86: 343–358.
9. European Glaucoma Society (2014): Classification and Terminology (Chapter 2). In: European Glaucoma Society (ed.) Terminology and guidelines for glaucoma. Savona, Italy: PubliComm 75–127.
10. Flammer J, Orgül S, Costa VP, Orzalesi N, Krieglstein GK, Serra LM, Renard JP & Stefánsson E (2002): The impact of ocular blood flow in glaucoma. Prog Retin Eye Res 21: 359–393.
11. Galassi F, Nuzzaci G, Sodi A, Casi P & Vielmo A (1992): Color Doppler imaging in evaluation of optic nerve blood supply in normal and glaucomatous subjects. Int Ophthalmol 16: 273–276.
12. Galassi F, Giambene B & Varriale R (2011): Systemic vascular dysregulation and retrobulbar hemodynamics in normal-tension glaucoma. Invest Ophthalmol Vis Sci 52: 4467–4471.
13. Geirsdottir A, Palsson O, Hardarson SH, Olafsdottir OB, Kristjansdottir JV & Stefansson E (2012): Retinal vessel oxygen saturation in healthy individuals. Invest Ophthalmol Vis Sci 53: 5433–5442.
14. Harris A, Topouzis F, Wilson MR et al. (2013): Association of the optic disc structure with the use of antihypertensive medications: the thessaloniki eye study. J Glaucoma 22: 526–531.
15. Huck A, Harris A, Siesky B, Kim N, Muchnik M, Kanakamedala P, Amireskandari A & Abrams-Tobe L (2014): Vascular considerations in glaucoma patients of African and European descent. Acta Ophthalmol 92: e336–e340.
16. Jampel HD (1997): Target pressure in glaucoma therapy. J Glaucoma 6: 133–138.
17. Konieczka K, Ritch R, Traverso CE et al. (2014): Flammer syndrome. EPMA J 5: 11.
18. Leske MC, Wu SY, Hennis A, Honkanen R, Nemesure B & BES Group (2008): Risk factors for incident open-angle glaucoma: the Barbados Eye Studies. Ophthalmology 115: 85–93.
19. Lin CC, Hu CC, Ho JD, Chiu HW & Lin HC (2013): Obstructive sleep apnea and increased risk of glaucoma: a population-based matched-cohort study. Ophthalmology 120: 1559–1564.
20. Marangoni D, Falsini B, Colotto A et al. (2012): Subfoveal choroidal blood flow and central retinal function in early glaucoma. Acta Ophthalmol 90: e288–e294.
21. Meng N, Zhang P, Huang H, Ma J, Zhang Y, Li H & Qu Y (2013): Color Doppler imaging analysis of retrobulbar blood flow velocities in primary open-angle glaucomatous eyes: a meta-analysis. PLoS ONE 8: e62723.
22. Mitchell P, Smith W, Attebo K & Healey PR (1996): Prevalence of open-angle glaucoma in Australia. Mountains The Blue Study Eye. Ophthalmology 103: 1661–1669.
23. Muskens RP, de Voogd S, Wolfs RC, Witteman JC, Hofman A, de Jong PT, Stricker BH & Jansonius NM (2007): Systemic antihypertensive medication and incident open-angle glaucoma. Ophthalmology 114: 2221–2226.
24. Nicolela MT, Hnik P & Drance SM (1996): Scanning laser Doppler flowmeter study of retinal and optic disk blood flow in glaucomatous patients. Am J Ophthalmol 122: 775–783.
25. Olafsdottir OB, Vandewalle E, Abegão Pinto L et al. (2014): Retinal oxygen metabolism in healthy subjects and glaucoma patients. Br J Ophthalmol 98: 329–333.
26. O'Neill RT & Temple R (2012): The prevention and treatment of missing data in clinical trials: an FDA perspective on the importance of dealing with it. Clin Pharmacol Ther 91: 550–554.
27. Palsson O, Geirsdottir A, Hardarson SH, Olafsdottir OB, Kristjansdottir JV & Stefansson E (2012): Retinal oximetry images must be standardized: a methodological analysis. Invest Ophthalmol Vis Sci 53: 1729–1733.
28. Quigley HA & Broman AT (2006): The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90: 262–267.
29. Stalmans I, Harris A, Vanbellinghen V, Zeyen T & Siesky B (2008): Ocular pulse amplitude in normal tension and primary open angle glaucoma. J Glaucoma 17: 403–407.
30. Stalmans I, Siesky B, Zeyen T, Fieuws S & Harris A (2009): Reproducibility of color Doppler imaging. Graefes Arch Clin Exp Ophthalmol 247: 1531–1538.
31. Stalmans I, Vandewalle E, Anderson DR et al. (2011): Use of colour Doppler imaging in ocular blood flow research. Acta Ophthalmol 89: e609–e630.
32. Tham YC, Li X, Wong TY, Quigley HA, Aung T & Cheng CY (2014): Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 121: 2081–2090.
33. Topouzis F, Wilson MR, Harris A et al. (2007): Prevalence of open-angle glaucoma in Greece: the Study Thessaloniki Eye. Am J Ophthalmol 144: 511–519.
34. Van Keer K, Abegão Pinto L, Willekens K, Stalmans I & Vandewalle E (2015): Correlation between peripapillary choroidal thickness and retinal vessel oxygen saturation in young healthy individuals and glaucoma patients. Invest Ophthalmol Vis Sci 56: 3758–3762.
35. Vandewalle E, Abegão Pinto L, Olafsdottir OB & Stalmans I (2013): Phenylephrine 5% added to tropicamide 0.5% eye drops does not influence retinal oxygen saturation values or retinal vessel diameter in glaucoma patients. Acta Ophthalmol 91: 733–737.
36. Vandewalle E, Abegão Pinto L, Olafsdottir OB et al. (2014): Oximetry in glaucoma: correlation of metabolic change with structural and functional damage. Acta Ophthalmol 92: 105–110.
37. Wang JJ, Mitchell P & Smith W (1997): Is there an association between migraine headache and open-angle glaucoma? Findings from the Blue Mountains Eye Study Ophthalmology 104: 1714–1719.
38. Wang YX, Xu L, Yang H & Jonas JB (2010): Prevalence of glaucoma in North China: the Beijing Eye Study. Am J Ophthalmol 150: 917–924.
39. Wolfs RC, Borger PH, Ramrattan RS et al. (2000): Changing views on open-angle glaucoma: definitions and prevalences-- The Rotterdam Study. Invest Ophthalmol Vis Sci 41: 3309–3321.
40. Yanagi M, Kawasaki R, Wang JJ, Wong TY, Crowston J & Kiuchi Y (2011): Vascular risk factors in glaucoma: a review. Clin Experiment Ophthalmol 39: 252–258.