-
1
-
-
0028889014
-
The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver
-
Akerboom T.P., Sies H., Ziegler D.M. The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver. Arch. Biochem. Biophys. 316:1995;220-226.
-
(1995)
Arch. Biochem. Biophys.
, vol.316
, pp. 220-226
-
-
Akerboom, T.P.1
Sies, H.2
Ziegler, D.M.3
-
2
-
-
0027261529
-
The mechanism of methyl mercury toxicity in isolated rat hepatocytes
-
Ashour H., Abdel-Rahman M., Khodair A. The mechanism of methyl mercury toxicity in isolated rat hepatocytes. Toxicol. Lett. 69:1993;87-96.
-
(1993)
Toxicol. Lett.
, vol.69
, pp. 87-96
-
-
Ashour, H.1
Abdel-Rahman, M.2
Khodair, A.3
-
3
-
-
0037051789
-
Methylmercury induces the opening of the permeability transition pore in rat liver mitochondria
-
Bragadin M., Marton D., Manente S., Grasso M., Toninello A. Methylmercury induces the opening of the permeability transition pore in rat liver mitochondria. J. Inorg. Biochem. 89:2002;159-162.
-
(2002)
J. Inorg. Biochem.
, vol.89
, pp. 159-162
-
-
Bragadin, M.1
Marton, D.2
Manente, S.3
Grasso, M.4
Toninello, A.5
-
5
-
-
0026640860
-
Characterisation and quantitation of a selenol intermediate in the reaction of ebselen with thiols
-
Cotgreave I.A., Morgenstern R., Engman L., Ahokas J. Characterisation and quantitation of a selenol intermediate in the reaction of ebselen with thiols. Chem. Biol. Interact. 84:1992;69-76.
-
(1992)
Chem. Biol. Interact.
, vol.84
, pp. 69-76
-
-
Cotgreave, I.A.1
Morgenstern, R.2
Engman, L.3
Ahokas, J.4
-
6
-
-
0037782283
-
Effects of prenatal exposure to methylmercury on dopamine-mediated locomotor activity and dopamine D2 receptor binding
-
Dare E., Fetissov S., Hokfelt T., Hall H., Ogren S.O., Ceccatelli S. Effects of prenatal exposure to methylmercury on dopamine-mediated locomotor activity and dopamine D2 receptor binding. Naunyn. Schmiedebergs Arch. Pharmacol. 367:2003;500-508.
-
(2003)
Naunyn. Schmiedebergs Arch. Pharmacol.
, vol.367
, pp. 500-508
-
-
Dare, E.1
Fetissov, S.2
Hokfelt, T.3
Hall, H.4
Ogren, S.O.5
Ceccatelli, S.6
-
7
-
-
0035918903
-
Tissue specific changes in the expression of glutamate-cysteine ligase mRNAs in mice exposed to methylmercury
-
Diaz D., Krejsa C.M., White C.C., Keener C.L., Farin F.M., Kavanagh T.J. Tissue specific changes in the expression of glutamate-cysteine ligase mRNAs in mice exposed to methylmercury. Toxicol. Lett. 122:2001;119-129.
-
(2001)
Toxicol. Lett.
, vol.122
, pp. 119-129
-
-
Diaz, D.1
Krejsa, C.M.2
White, C.C.3
Keener, C.L.4
Farin, F.M.5
Kavanagh, T.J.6
-
9
-
-
0024412233
-
Expedient synthesis of ebselen and related-compounds
-
Engman L., Hallberg A. Expedient synthesis of ebselen and related-compounds. J. Org. Chem. 54:1989;2964-2966.
-
(1989)
J. Org. Chem.
, vol.54
, pp. 2964-2966
-
-
Engman, L.1
Hallberg, A.2
-
10
-
-
84983719135
-
Selenoxides inhibit δ-aminolevulinic acid dehydratase
-
Farina M., Folmer V., Bolzan R.C., Andrade L.H., Zeni G., Braga A.L., Rocha J.B.T. Selenoxides inhibit δ-aminolevulinic acid dehydratase. Toxicol. Lett. 119:2001;27-37.
-
(2001)
Toxicol. Lett.
, vol.119
, pp. 27-37
-
-
Farina, M.1
Folmer, V.2
Bolzan, R.C.3
Andrade, L.H.4
Zeni, G.5
Braga, A.L.6
Rocha, J.B.T.7
-
11
-
-
84984538861
-
Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: Modulatory effect of ebselen
-
Farina M., Dahm K.C.S., Schwalm F.D., Brusque A.M., Frizzo M.E.S., Zeni G., Souza D.O., Rocha J.B.T. Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen. Toxicol. Sci. 73:2003a;135-140.
-
(2003)
Toxicol. Sci.
, vol.73
, pp. 135-140
-
-
Farina, M.1
Dahm, K.C.S.2
Schwalm, F.D.3
Brusque, A.M.4
Frizzo, M.E.S.5
Zeni, G.6
Souza, D.O.7
Rocha, J.B.T.8
-
12
-
-
84984536045
-
Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice
-
Farina M., Frizzo M.E.S., Soares F.A.A., Schwalm F.D., Dietrich M.O., Zeni G., Rocha J.B.T., Souza D.O.G. Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice. Toxicol. Lett. 144:2003b;351-357.
-
(2003)
Toxicol. Lett.
, vol.144
, pp. 351-357
-
-
Farina, M.1
Frizzo, M.E.S.2
Soares, F.A.A.3
Schwalm, F.D.4
Dietrich, M.O.5
Zeni, G.6
Rocha, J.B.T.7
Souza, D.O.G.8
-
13
-
-
0037903546
-
Neurobehavioral changes in mice chronically exposed to methylmercury during fetal and early post-natal development
-
Goulet S., Dore F.Y., Mirault M.E. Neurobehavioral changes in mice chronically exposed to methylmercury during fetal and early post-natal development. Neurotoxicol. Teratol. 25:2003;335-347.
-
(2003)
Neurotoxicol. Teratol.
, vol.25
, pp. 335-347
-
-
Goulet, S.1
Dore, F.Y.2
Mirault, M.E.3
-
14
-
-
0028821638
-
Minamata disease: Methylmercury poisoning in Japan caused by environmental pollution
-
Harada M. Minamata disease: methylmercury poisoning in Japan caused by environmental pollution. Crit. Rev. Toxicol. 25:1995;1-24.
-
(1995)
Crit. Rev. Toxicol.
, vol.25
, pp. 1-24
-
-
Harada, M.1
-
15
-
-
0032581362
-
Ebselen, a selenium-containing redox drug, releases zinc from metallothionein
-
Jacob C., Maret W., Vallee B.L. Ebselen, a selenium-containing redox drug, releases zinc from metallothionein. Biochem. Biophys. Res. Commun. 248:1998;569-573.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.248
, pp. 569-573
-
-
Jacob, C.1
Maret, W.2
Vallee, B.L.3
-
16
-
-
18244415707
-
Defenses against peroxynitrite: Selenocompounds and flavonoids
-
Klotz L.O., Sies H. Defenses against peroxynitrite: selenocompounds and flavonoids. Toxicol. Lett. 140-141:2003;125-132.
-
(2003)
Toxicol. Lett.
, vol.140-141
, pp. 125-132
-
-
Klotz, L.O.1
Sies, H.2
-
17
-
-
0035865777
-
Ebselen prevents early alcohol-induced liver injury in rats
-
Kono H., Arteel G.E., Rusyn I., Sies H., Thurman R.G. Ebselen prevents early alcohol-induced liver injury in rats. Free Radic. Biol. Med. 30:2001;403-411.
-
(2001)
Free Radic. Biol. Med.
, vol.30
, pp. 403-411
-
-
Kono, H.1
Arteel, G.E.2
Rusyn, I.3
Sies, H.4
Thurman, R.G.5
-
18
-
-
0002657209
-
Specific features of metal absorption in suckling animals
-
Clarkson, T.W., Nordberg, G.F., Sager, R. (Eds.), Plenum Press, New York
-
Kostial, K., 1983. Specific features of metal absorption in suckling animals. In: Clarkson, T.W., Nordberg, G.F., Sager, R. (Eds.), Reproductive and Developmental Toxicity of Metals, Plenum Press, New York. pp. 272-744.
-
(1983)
Reproductive and Developmental Toxicity of Metals
, pp. 272-744
-
-
Kostial, K.1
-
19
-
-
0033600277
-
The changing landscape of ischaemic brain injury mechanisms
-
Lee J.M., Zipfel G.J., Choi D.W. The changing landscape of ischaemic brain injury mechanisms. Nature. 399:1999;A7-A14.
-
(1999)
Nature
, vol.399
-
-
Lee, J.M.1
Zipfel, G.J.2
Choi, D.W.3
-
20
-
-
0029833064
-
Lipid peroxidation in liver of rats administrated with methyl mercuric chloride
-
Lin T.H., Huang Y.L., Huang S.F. Lipid peroxidation in liver of rats administrated with methyl mercuric chloride. Biol. Trace Elem. Res. 54:1996;33-41.
-
(1996)
Biol. Trace Elem. Res.
, vol.54
, pp. 33-41
-
-
Lin, T.H.1
Huang, Y.L.2
Huang, S.F.3
-
22
-
-
0035106674
-
Current status and perspectives of neuroprotection in ischemic stroke treatment
-
Martinez-Vila E., Sieira P.I. Current status and perspectives of neuroprotection in ischemic stroke treatment. Cerebrovasc. Dis. 11:2001;60-70.
-
(2001)
Cerebrovasc. Dis.
, vol.11
, pp. 60-70
-
-
Martinez-Vila, E.1
Sieira, P.I.2
-
23
-
-
84984578824
-
Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice
-
Meotti F.C., Borges V.C., Zeni G., Rocha J.B.T., Nogueira C.W. Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice. Toxicol. Lett. 143:2003;9-16.
-
(2003)
Toxicol. Lett.
, vol.143
, pp. 9-16
-
-
Meotti, F.C.1
Borges, V.C.2
Zeni, G.3
Rocha, J.B.T.4
Nogueira, C.W.5
-
24
-
-
0035906526
-
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity
-
Miyamoto K., Nakanishi H., Moriguchi S., Fukuyama N., Eto K., Wakamiya J., Murao K., Arimura K., Osame M. Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity. Brain Res. 901:2001;252-258.
-
(2001)
Brain Res.
, vol.901
, pp. 252-258
-
-
Miyamoto, K.1
Nakanishi, H.2
Moriguchi, S.3
Fukuyama, N.4
Eto, K.5
Wakamiya, J.6
Murao, K.7
Arimura, K.8
Osame, M.9
-
25
-
-
0021185122
-
A novel biologically active seleno-organic compound-I: Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (ebselen)
-
Müller A., Cadenas E., Graf P., Sies H. A novel biologically active seleno-organic compound-I: glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (ebselen). Biochem. Pharmacol. 33:1984;3235-3239.
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 3235-3239
-
-
Müller, A.1
Cadenas, E.2
Graf, P.3
Sies, H.4
-
26
-
-
0345854663
-
Developmental neurotoxicity following prenatal exposures to methylmercury and PCBs in humans from epidemiological studies
-
Nakai K., Satoh H. Developmental neurotoxicity following prenatal exposures to methylmercury and PCBs in humans from epidemiological studies. Tohoku. J. Exp. Med. 196:2002;89-98.
-
(2002)
Tohoku. J. Exp. Med.
, vol.196
, pp. 89-98
-
-
Nakai, K.1
Satoh, H.2
-
27
-
-
0018384650
-
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
-
Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95:1979;351-358.
-
(1979)
Anal. Biochem.
, vol.95
, pp. 351-358
-
-
Ohkawa, H.1
Ohishi, N.2
Yagi, K.3
-
28
-
-
0031039324
-
Ebselen, a novel anti-oxidant compound, protects the rat liver from ischemia reperfusion injury
-
Ozaki M., Nakamura M., Teraoka S., Ota K. Ebselen, a novel anti-oxidant compound, protects the rat liver from ischemia reperfusion injury. Transpl. Int. 10:1997;96-102.
-
(1997)
Transpl. Int.
, vol.10
, pp. 96-102
-
-
Ozaki, M.1
Nakamura, M.2
Teraoka, S.3
Ota, K.4
-
29
-
-
0014108436
-
Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
-
Pagalia D.E., Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70:1967;158-169.
-
(1967)
J. Lab. Clin. Med.
, vol.70
, pp. 158-169
-
-
Pagalia, D.E.1
Valentine, W.N.2
-
30
-
-
0033994250
-
Ebselen: Prospective therapy for cerebral ischaemia
-
Parnham M., Sies H. Ebselen: prospective therapy for cerebral ischaemia. Expert. Opin. Investig. Drugs. 9:2000;607-619.
-
(2000)
Expert. Opin. Investig. Drugs.
, vol.9
, pp. 607-619
-
-
Parnham, M.1
Sies, H.2
-
31
-
-
0027262157
-
Effects of methyl mercury in postnatal developing rats
-
Sakamoto M., Nakano A., Kajiwara Y., Naruse I., Fujisaki T. Effects of methyl mercury in postnatal developing rats. Environ. Res. 61:1993;43-50.
-
(1993)
Environ. Res.
, vol.61
, pp. 43-50
-
-
Sakamoto, M.1
Nakano, A.2
Kajiwara, Y.3
Naruse, I.4
Fujisaki, T.5
-
32
-
-
0026102123
-
Oxidative mechanisms underlying methyl mercury neurotoxicity
-
Sarafian T., Verity M.A. Oxidative mechanisms underlying methyl mercury neurotoxicity. Int. J. Dev. Neurosci. 9:1991;147-153.
-
(1991)
Int. J. Dev. Neurosci.
, vol.9
, pp. 147-153
-
-
Sarafian, T.1
Verity, M.A.2
-
33
-
-
0018117523
-
Selenium protection against mercury toxicity: High binding affinity of methylmercury by selenium-containing ligands in comparison with sulfur-containing ligands
-
Sugiura Y., Tamai Y., Takaka H. Selenium protection against mercury toxicity: high binding affinity of methylmercury by selenium-containing ligands in comparison with sulfur-containing ligands. Bioinorg. Chem. 9:1978;167-180.
-
(1978)
Bioinorg. Chem.
, vol.9
, pp. 167-180
-
-
Sugiura, Y.1
Tamai, Y.2
Takaka, H.3
-
34
-
-
0023242350
-
The role of selenium peroxidases in the protection against oxidative damage of membranes
-
Ursini F., Bindoli A. The role of selenium peroxidases in the protection against oxidative damage of membranes. Chem. Phys. Lipids. 44:1987;255-276.
-
(1987)
Chem. Phys. Lipids.
, vol.44
, pp. 255-276
-
-
Ursini, F.1
Bindoli, A.2
-
35
-
-
0036483408
-
Neurobehavioral performance of Inuit children with increased prenatal exposure to methylmercury
-
Weihe P., Hansen J.C., Murata K., Debes F., Jorgensen P., Steuerwald U., White R.F., Grandjean P. Neurobehavioral performance of Inuit children with increased prenatal exposure to methylmercury. Int. J. Circumpolar Health. 61:2002;41-49.
-
(2002)
Int. J. Circumpolar Health
, vol.61
, pp. 41-49
-
-
Weihe, P.1
Hansen, J.C.2
Murata, K.3
Debes, F.4
Jorgensen, P.5
Steuerwald, U.6
White, R.F.7
Grandjean, P.8
-
36
-
-
0034652202
-
Ebselen induces apoptosis in HepG(2) cells through rapid depletion of intracellular thiols
-
Yang C.F., Shen H.M., Ong C.N. Ebselen induces apoptosis in HepG(2) cells through rapid depletion of intracellular thiols. Arch. Biochem. Biophys. 374:2000a;142-152.
-
(2000)
Arch. Biochem. Biophys.
, vol.374
, pp. 142-152
-
-
Yang, C.F.1
Shen, H.M.2
Ong, C.N.3
-
37
-
-
0034663082
-
Intracellular thiol depletion causes mitochondrial permeability transition in ebselen-induced apoptosis
-
Yang C.F., Shen H.M., Ong C.N. Intracellular thiol depletion causes mitochondrial permeability transition in ebselen-induced apoptosis. Arch. Biochem. Biophys. 380:2000b;319-330.
-
(2000)
Arch. Biochem. Biophys.
, vol.380
, pp. 319-330
-
-
Yang, C.F.1
Shen, H.M.2
Ong, C.N.3
-
38
-
-
0020535002
-
Stimulation of lipid peroxidation by methyl mercury in rats
-
Yonaha M., Saito M., Sagai M. Stimulation of lipid peroxidation by methyl mercury in rats. Life Sci. 32:1983;1507-1514.
-
(1983)
Life Sci.
, vol.32
, pp. 1507-1514
-
-
Yonaha, M.1
Saito, M.2
Sagai, M.3
|