The prescription pattern of acetaminophen and non-steroidal anti-inflammatory drugs in patients with liver cirrhosis

Journal of Korean Medical Science

Volumn 31, Issue 10, 2016, Pages 1604-1610

  Hong, Young Mi ^a   Yoon, Ki Tae ^a   Heo, Jeong ^b   Woo, Hyun Young ^b   Lim, Won ^b   An, Dae Seong ^a   Han, Jun Hee ^a   Cho, Mong ^a  

^a Yangsan Hospital   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

Author keywords

Acetaminophen; Liver cirrhosis; Non Steroid Anti Inflammatory Drugs (NSAIDs); Pattern of prescription

Indexed keywords

ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL;

AGED; CHEMICAL AND DRUG INDUCED LIVER INJURY; COMPLICATION; FACTUAL DATABASE; FEMALE; HUMAN; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PRESCRIPTION; REGISTER; STATISTICS AND NUMERICAL DATA; VIRUS HEPATITIS;

ACETAMINOPHEN; AGED; ANALGESICS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMICAL AND DRUG INDUCED LIVER INJURY; DATABASES, FACTUAL; DRUG PRESCRIPTIONS; FEMALE; HEPATITIS, VIRAL, HUMAN; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; REGISTRIES;

EID: 84983631045     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2016.31.10.1604     Document Type: Article

References (23)

1. Heard K, Green JL, Bailey JE, Bogdan GM, Dart RC. A randomized trial to determine the change in alanine aminotransferase during 10 days of paracetamol (acetaminophen) administration in subjects who consume moderate amounts of alcohol. Aliment Pharmacol Ther 2007; 26: 283-90.
2. Dwyer JP, Jayasekera C, Nicoll A. Analgesia for the cirrhotic patient: a literature review and recommendations. J Gastroenterol Hepatol 2014; 29: 1356-60.
3. Lewis JH, Stine JG. Review article: prescribing medications in patients with cirrhosis-a practical guide. Aliment Pharmacol Ther 2013; 37: 1132-56.
4. Imani F, Motavaf M, Safari S, Alavian SM. The therapeutic use of analgesics in patients with liver cirrhosis: a literature review and evidence-based recommendations. Hepat Mon 2014; 14: e23539.
5. Rossi S, Assis DN, Awsare M, Brunner M, Skole K, Rai J, Andrel J, Herrine SK, Reddy RK, Navarro VJ. Use of over-the-counter analgesics in patients with chronic liver disease: physicians' recommendations. Drug Saf 2008; 31: 261-70.
6. Khalid SK, Lane J, Navarro V, Garcia-Tsao G. Use of over-the-counter analgesics is not associated with acute decompensation in patients with cirrhosis. Clin Gastroenterol Hepatol 2009; 7: 994-9.
7. WHO Collaborating Center for Drug Statistics Methodology. Defined daily dose: definition and general considerations. Available at http://www.whocc.no/ddd/definition_and_general_considera/[accessed on 1 January 2016].
8. D'Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006; 44: 217-31.
9. Moreau R, Jalan R, Gines P, Pavesi M, Angeli P, Cordoba J, Durand F, Gustot T, Saliba F, Domenicali M, et al. Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. Gastroenterology 2013; 144: 1426-37, 1437.e1-9.
10. Zimmerman HJ, Maddrey WC. Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure. Hepatology 1995; 22: 767-73.
11. Lucena MI, Andrade RJ, Tognoni G, Hidalgo R, Sanchez de la Cuesta F; Spanish Collaborative Study Group on Therapeutic Management of Liver Diseases. Drug use for non-hepatic associated conditions in patients with liver cirrhosis. Eur J Clin Pharmacol 2003; 59: 71-6.
12. Watkins PB, Kaplowitz N, Slattery JT, Colonese CR, Colucci SV, Stewart PW, Harris SC. Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA 2006; 296: 87-93.
13. Schoene B, Fleischmann RA, Remmer H, von Oldershausen HF. Determination of drug metabolizing enzymes in needle biopsies of human liver. Eur J Clin Pharmacol 1972; 4: 65-73.
14. Williams RL, Upton RA, Cello JP, Jones RM, Blitstein M, Kelly J, Nierenburg D. Naproxen disposition in patients with alcoholic cirrhosis. Eur J Clin Pharmacol 1984; 27: 291-6.
15. Carson JL, Strom BL, Duff A, Gupta A, Das K. Safety of nonsteroidal anti-inflammatory drugs with respect to acute liver disease. Arch Intern Med 1993; 153: 1331-6.
16. Fry SW, Seeff LB. Hepatotoxicity of analgesics and anti-inflammatory agents. Gastroenterol Clin North Am 1995; 24: 875-905.
17. Mirouze D, Zipser RD, Reynolds TB. Effect of inhibitors of prostaglandin synthesis on induced diuresis in cirrhosis. Hepatology 1983; 3: 50-5.
18. Boyer TD, Zia P, Reynolds TB. Effect of indomethacin and prostaglandin A1 on renal function and plasma renin activity in alcoholic liver disease. Gastroenterology 1979; 77: 215-22.
19. Schafer AI. Effects of nonsteroidal antiinflammatory drugs on platelet function and systemic hemostasis. J Clin Pharmacol 1995; 35: 209-19.
20. Brater DC, Anderson SA, Brown-Cartwright D. Reversible acute decrease in renal function by NSAIDs in cirrhosis. Am J Med Sci 1987; 294: 168-74.
21. Clària J, Kent JD, López-Parra M, Escolar G, Ruiz-Del-Arbol L, Ginès P, Jiménez W, Vucelic B, Arroyo V. Effects of celecoxib and naproxen on renal function in nonazotemic patients with cirrhosis and ascites. Hepatology 2005; 41: 579-87.
22. Lee YC, Chang CH, Lin JW, Chen HC, Lin MS, Lai MS. Non-steroidal anti-inflammatory drugs use and risk of upper gastrointestinal adverse events in cirrhotic patients. Liver Int 2012; 32: 859-66.
23. Luo JC, Leu HB, Hou MC, Huang CC, Lin HC, Lee FY, Chang FY, Chan WL, Lin SJ, Chen JW. Cirrhotic patients at increased risk of peptic ulcer bleeding: a nationwide population-based cohort study. Aliment Pharmacol Ther 2012; 36: 542-50.