-
1
-
-
35448981935
-
Autophagy: from phenomenology to molecular understanding in less than a decade
-
17712358
-
D.J.Klionsky. Autophagy:from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 2007; 8:931-7; PMID:17712358; http://dx.doi.org/10.1038/nrm2245
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 931-937
-
-
Klionsky, D.J.1
-
2
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
18188003
-
D.J.Klionsky, H.Abeliovich, P.Agostinis, D.K.Agrawal, G.Aliev, D.S.Askew, M.Baba, E.H.Baehrecke, B.A.Bahr, A.Ballabio, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4:151-75; PMID:18188003; http://dx.doi.org/10.4161/auto.5338
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
-
3
-
-
47249094223
-
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
-
18421301
-
F.Scarlatti, R.Maffei, I.Beau, P.Codogno, R.Ghidoni. Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ 2008; 15:1318-29; PMID:18421301; http://dx.doi.org/10.1038/cdd.2008.51
-
(2008)
Cell Death Differ
, vol.15
, pp. 1318-1329
-
-
Scarlatti, F.1
Maffei, R.2
Beau, I.3
Codogno, P.4
Ghidoni, R.5
-
4
-
-
84856748733
-
Cell death by autophagy: facts and apparent artefacts
-
22052193
-
D.Denton, S.Nicolson, S.Kumar. Cell death by autophagy:facts and apparent artefacts. Cell Death Differ 2012; 19:87-95; PMID:22052193; http://dx.doi.org/10.1038/cdd.2011.146
-
(2012)
Cell Death Differ
, vol.19
, pp. 87-95
-
-
Denton, D.1
Nicolson, S.2
Kumar, S.3
-
5
-
-
84887437596
-
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
-
24113172
-
X.Sui, R.Chen, Z.Wang, Z.Huang, N.Kong, M.Zhang, W.Han, F.Lou, J.Yang, Q.Shang, et al. Autophagy and chemotherapy resistance:a promising therapeutic target for cancer treatment. Cell Death Dis 2013; 4:e838; PMID:24113172; http://dx.doi.org/10.1038/cddis.2013.350
-
(2013)
Cell Death Dis
, vol.4
, pp. e838
-
-
Sui, X.1
Chen, R.2
Wang, Z.3
Huang, Z.4
Kong, N.5
Zhang, M.6
Han, W.7
Lou, F.8
Yang, J.9
Shang, Q.10
-
7
-
-
34249863298
-
Autophagy suppresses tumor progression by limiting chromosomal instability
-
17510285
-
R.Mathew, S.Kongara, B.Beaudoin, C.M.Karp, K.Bray, K.Degenhardt, G.Chen, S.Jin, E.White. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev 2007; 21:1367-81; PMID:17510285; http://dx.doi.org/10.1101/gad.1545107
-
(2007)
Genes Dev
, vol.21
, pp. 1367-1381
-
-
Mathew, R.1
Kongara, S.2
Beaudoin, B.3
Karp, C.M.4
Bray, K.5
Degenhardt, K.6
Chen, G.7
Jin, S.8
White, E.9
-
8
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of P62
-
19524509
-
R.Mathew, C.M.Karp, B.Beaudoin, N.Vuong, G.Chen, H.Y.Chen, K.Bray, A.Reddy, G.Bhanot, C.Gelinas, et al. Autophagy suppresses tumorigenesis through elimination of P62. Cell 2009; 137:1062-75; PMID:19524509; http://dx.doi.org/10.1016/j.cell.2009.03.048
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
Chen, H.Y.6
Bray, K.7
Reddy, A.8
Bhanot, G.9
Gelinas, C.10
-
9
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
14657337
-
Z.Yue, S.Jin, C.Yang, A.J.Levine, N.Heintz. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 2003; 100:15077-82; PMID:14657337; http://dx.doi.org/10.1073/pnas.2436255100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
10
-
-
77956400210
-
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFkappaB activation in the tumor stromal microenvironment
-
20855962
-
U.E.Martinez-Outschoorn, C.Trimmer, Z.Lin, D.Whitaker-Menezes, B.Chiavarina, J.Zhou, C.Wang, S.Pavlides, M.P.Martinez-Cantarin, F.Capozza, et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival:Role of hypoxia, HIF1 induction and NFkappaB activation in the tumor stromal microenvironment. Cell Cycle 2010; 9:3515-33; PMID:20855962; http://dx.doi.org/10.4161/cc.9.17.12928
-
(2010)
Cell Cycle
, vol.9
, pp. 3515-3533
-
-
Martinez-Outschoorn, U.E.1
Trimmer, C.2
Lin, Z.3
Whitaker-Menezes, D.4
Chiavarina, B.5
Zhou, J.6
Wang, C.7
Pavlides, S.8
Martinez-Cantarin, M.P.9
Capozza, F.10
-
11
-
-
77956399348
-
HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis
-
20864819
-
B.Chiavarina, D.Whitaker-Menezes, G.Migneco, U.E.Martinez-Outschoorn, S.Pavlides, A.Howell, H.B.Tanowitz, M.C.Casimiro, C.Wang, R.G.Pestell, et al. HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells:Autophagy drives compartment-specific oncogenesis. Cell Cycle 2010; 9:3534-51; PMID:20864819; http://dx.doi.org/10.4161/cc.9.17.12908
-
(2010)
Cell Cycle
, vol.9
, pp. 3534-3551
-
-
Chiavarina, B.1
Whitaker-Menezes, D.2
Migneco, G.3
Martinez-Outschoorn, U.E.4
Pavlides, S.5
Howell, A.6
Tanowitz, H.B.7
Casimiro, M.C.8
Wang, C.9
Pestell, R.G.10
-
12
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
11057897
-
R.J.Davis. Signal transduction by the JNK group of MAP kinases. Cell 2000; 103:239-52; PMID:11057897; http://dx.doi.org/10.1016/S0092-8674(00)00116-1
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
13
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
12471242
-
G.L.Johnson, R.Lapadat. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002; 298:1911-2; PMID:12471242; http://dx.doi.org/10.1126/science.1072682
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
14
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
-
11294822
-
G.Pearson, F.Robinson, T.Beers Gibson, B.E.Xu, M.Karandikar, K.Berman, M.H.Cobb. Mitogen-activated protein (MAP) kinase pathways:regulation and physiological functions. Endocr Rev 2001; 22:153-83; PMID:11294822
-
(2001)
Endocr Rev
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Beers Gibson, T.3
Xu, B.E.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
15
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
11242034
-
L.Chang, M.Karin. Mammalian MAP kinase signalling cascades. Nature 2001; 410:37-40; PMID:11242034; http://dx.doi.org/10.1038/35065000
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
16
-
-
0141723393
-
Role of JNK in tumor development
-
12734425
-
N.J.Kennedy, R.J.Davis. Role of JNK in tumor development. Cell Cycle 2003; 2:199-201; PMID:12734425
-
(2003)
Cell Cycle
, vol.2
, pp. 199-201
-
-
Kennedy, N.J.1
Davis, R.J.2
-
17
-
-
84871458229
-
Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway
-
23116132
-
J.F.Moruno-Manchon, E.Perez-Jimenez, E.Knecht. Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway. Biochem J 2013; 449:497-506; PMID:23116132; http://dx.doi.org/10.1042/BJ20121122
-
(2013)
Biochem J
, vol.449
, pp. 497-506
-
-
Moruno-Manchon, J.F.1
Perez-Jimenez, E.2
Knecht, E.3
-
18
-
-
84863610034
-
IFN-gamma elicits macrophage autophagy via the p38 MAPK signaling pathway
-
22675202
-
T.Matsuzawa, B.H.Kim, A.R.Shenoy, S.Kamitani, M.Miyake, J.D.Macmicking. IFN-gamma elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol 2012; 189:813-8; PMID:22675202; http://dx.doi.org/10.4049/jimmunol.1102041
-
(2012)
J Immunol
, vol.189
, pp. 813-818
-
-
Matsuzawa, T.1
Kim, B.H.2
Shenoy, A.R.3
Kamitani, S.4
Miyake, M.5
Macmicking, J.D.6
-
19
-
-
0038269032
-
Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells
-
12609989
-
S.Pattingre, C.Bauvy, P.Codogno. Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells. The J Biol Chem 2003; 278:16667-74; PMID:12609989; http://dx.doi.org/10.1074/jbc.M210998200
-
(2003)
The J Biol Chem
, vol.278
, pp. 16667-16674
-
-
Pattingre, S.1
Bauvy, C.2
Codogno, P.3
-
20
-
-
33845693412
-
Diverse physiological functions for dual-specificity MAP kinase phosphatases
-
17093265
-
R.J.Dickinson, S.M.Keyse. Diverse physiological functions for dual-specificity MAP kinase phosphatases. J Cell Sci 2006; 119:4607-15; PMID:17093265; http://dx.doi.org/10.1242/jcs.03266
-
(2006)
J Cell Sci
, vol.119
, pp. 4607-4615
-
-
Dickinson, R.J.1
Keyse, S.M.2
-
21
-
-
0022335639
-
Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells
-
3841511
-
L.F.Lau, D.Nathans. Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells. EMBO J 1985; 4:3145-51; PMID:3841511
-
(1985)
EMBO J
, vol.4
, pp. 3145-3151
-
-
Lau, L.F.1
Nathans, D.2
-
22
-
-
0026570140
-
cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein
-
1741163
-
C.H.Charles, A.S.Abler, L.F.Lau. cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene 1992; 7:187-90; PMID:1741163
-
(1992)
Oncogene
, vol.7
, pp. 187-190
-
-
Charles, C.H.1
Abler, A.S.2
Lau, L.F.3
-
23
-
-
0026779540
-
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
-
1406996
-
S.M.Keyse, E.A.Emslie. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature 1992; 359:644-7; PMID:1406996; http://dx.doi.org/10.1038/359644a0
-
(1992)
Nature
, vol.359
, pp. 644-647
-
-
Keyse, S.M.1
Emslie, E.A.2
-
24
-
-
0028924419
-
Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation
-
7721728
-
Y.Liu, M.Gorospe, C.Yang, N.J.Holbrook. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation. J Biol Chem 1995; 270:8377-80; PMID:7721728; http://dx.doi.org/10.1074/jbc.270.15.8377
-
(1995)
J Biol Chem
, vol.270
, pp. 8377-8380
-
-
Liu, Y.1
Gorospe, M.2
Yang, C.3
Holbrook, N.J.4
-
25
-
-
0027358722
-
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
-
8221888
-
H.Sun, C.H.Charles, L.F.Lau, N.K.Tonks. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 1993; 75:487-93; PMID:8221888; http://dx.doi.org/10.1016/0092-8674(93)90383-2
-
(1993)
Cell
, vol.75
, pp. 487-493
-
-
Sun, H.1
Charles, C.H.2
Lau, L.F.3
Tonks, N.K.4
-
26
-
-
0027261369
-
Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth
-
8355678
-
T.Noguchi, R.Metz, L.Chen, M.G.Mattei, D.Carrasco, R.Bravo. Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth. Mol Cell Biol 1993; 13:5195-205; PMID:8355678; http://dx.doi.org/10.1128/MCB.13.9.5195
-
(1993)
Mol Cell Biol
, vol.13
, pp. 5195-5205
-
-
Noguchi, T.1
Metz, R.2
Chen, L.3
Mattei, M.G.4
Carrasco, D.5
Bravo, R.6
-
27
-
-
0030794511
-
Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
-
9202001
-
C.C.Franklin, A.S.Kraft. Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J Biol Chem 1997; 272:16917-23; PMID:9202001; http://dx.doi.org/10.1074/jbc.272.27.16917
-
(1997)
J Biol Chem
, vol.272
, pp. 16917-16923
-
-
Franklin, C.C.1
Kraft, A.S.2
-
28
-
-
0029060984
-
Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts
-
7761091
-
J.M.Brondello, F.R.McKenzie, H.Sun, N.K.Tonks, J.Pouyssegur. Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts. Oncogene 1995; 10:1895-904; PMID:7761091
-
(1995)
Oncogene
, vol.10
, pp. 1895-1904
-
-
Brondello, J.M.1
McKenzie, F.R.2
Sun, H.3
Tonks, N.K.4
Pouyssegur, J.5
-
29
-
-
4444240191
-
The functional interactions between the p53 and MAPK signaling pathways
-
14764989
-
G.S.Wu. The functional interactions between the p53 and MAPK signaling pathways. Cancer Bio Ther 2004; 3:156-61; PMID:14764989; http://dx.doi.org/10.4161/cbt.3.2.614
-
(2004)
Cancer Bio Ther
, vol.3
, pp. 156-161
-
-
Wu, G.S.1
-
30
-
-
0142039878
-
The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation
-
12890671
-
M.Li, J.Y.Zhou, Y.Ge, L.H.Matherly, G.S.Wu. The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation. J Biol Chem 2003; 278:41059-68; PMID:12890671; http://dx.doi.org/10.1074/jbc.M307149200
-
(2003)
J Biol Chem
, vol.278
, pp. 41059-41068
-
-
Li, M.1
Zhou, J.Y.2
Ge, Y.3
Matherly, L.H.4
Wu, G.S.5
-
31
-
-
0032539919
-
Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis
-
9501207
-
C.C.Franklin, S.Srikanth, A.S.Kraft. Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis. Proc Natl Acad Sci USA 1998; 95:3014-9; PMID:9501207; http://dx.doi.org/10.1073/pnas.95.6.3014
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3014-3019
-
-
Franklin, C.C.1
Srikanth, S.2
Kraft, A.S.3
-
32
-
-
0034718760
-
CL100/MKP-1 JNK activation and apoptosis in response to cisplatin
-
11064451
-
I.Sanchez-Perez, M.Martinez-Gomariz, D.Williams, S.M.Keyse, R.Perona. CL100/MKP-1 JNK activation and apoptosis in response to cisplatin. Oncogene 2000; 19:5142-52; PMID:11064451; http://dx.doi.org/10.1038/sj.onc.1203887
-
(2000)
Oncogene
, vol.19
, pp. 5142-5152
-
-
Sanchez-Perez, I.1
Martinez-Gomariz, M.2
Williams, D.3
Keyse, S.M.4
Perona, R.5
-
33
-
-
33744926726
-
MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer
-
16462770
-
S.Chattopadhyay, R.Machado-Pinilla, C.Manguan-Garcia, C.Belda-Iniesta, C.Moratilla, P.Cejas, J.A.Fresno-Vara, J.de Castro-Carpeno, E.Casado, M.Nistal, et al. MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer. Oncogene 2006; 25:3335-45; PMID:16462770; http://dx.doi.org/10.1038/sj.onc.1209364
-
(2006)
Oncogene
, vol.25
, pp. 3335-3345
-
-
Chattopadhyay, S.1
Machado-Pinilla, R.2
Manguan-Garcia, C.3
Belda-Iniesta, C.4
Moratilla, C.5
Cejas, P.6
Fresno-Vara, J.A.7
de Castro-Carpeno, J.8
Casado, E.9
Nistal, M.10
-
34
-
-
0037430452
-
Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer
-
12618338
-
H.Y.Wang, Z.Cheng, C.C.Malbon. Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer. Cancer Lett 2003; 191:229-37; PMID:12618338; http://dx.doi.org/10.1016/S0304-3835(02)00612-2
-
(2003)
Cancer Lett
, vol.191
, pp. 229-237
-
-
Wang, H.Y.1
Cheng, Z.2
Malbon, C.C.3
-
35
-
-
36148978132
-
Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer
-
17717636
-
G.S.Wu. Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer. Cancer Metastasis Rev 2007; 26:579-85; PMID:17717636; http://dx.doi.org/10.1007/s10555-007-9079-6
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 579-585
-
-
Wu, G.S.1
-
36
-
-
66149167313
-
Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin
-
19417026
-
F.Rojo, I.Gonzalez-Navarrete, R.Bragado, A.Dalmases, S.Menendez, M.Cortes-Sempere, C.Suarez, C.Oliva, S.Servitja, V.Rodriguez-Fanjul, et al. Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin. Clin Cancer Res 2009; 15:3530-9; PMID:19417026; http://dx.doi.org/10.1158/1078-0432.CCR-08-2070
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3530-3539
-
-
Rojo, F.1
Gonzalez-Navarrete, I.2
Bragado, R.3
Dalmases, A.4
Menendez, S.5
Cortes-Sempere, M.6
Suarez, C.7
Oliva, C.8
Servitja, S.9
Rodriguez-Fanjul, V.10
-
37
-
-
33748995966
-
Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance
-
16951204
-
Z.Wang, J.Xu, J.Y.Zhou, Y.Liu, G.S.Wu. Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res 2006; 66:8870-7; PMID:16951204; http://dx.doi.org/10.1158/0008-5472.CAN-06-1280
-
(2006)
Cancer Res
, vol.66
, pp. 8870-8877
-
-
Wang, Z.1
Xu, J.2
Zhou, J.Y.3
Liu, Y.4
Wu, G.S.5
-
38
-
-
37549025064
-
ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells
-
18089824
-
J.Wang, J.Y.Zhou, G.S.Wu. ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells. Cancer Res 2007; 67:11933-41; PMID:18089824; http://dx.doi.org/10.1158/0008-5472.CAN-07-5185
-
(2007)
Cancer Res
, vol.67
, pp. 11933-11941
-
-
Wang, J.1
Zhou, J.Y.2
Wu, G.S.3
-
39
-
-
0035912780
-
The target of rapamycin (TOR) proteins
-
11416184
-
B.Raught, A.C.Gingras, N.Sonenberg. The target of rapamycin (TOR) proteins. Proc Natl Acad Sci U S A 2001; 98:7037-44; PMID:11416184; http://dx.doi.org/10.1073/pnas.121145898
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7037-7044
-
-
Raught, B.1
Gingras, A.C.2
Sonenberg, N.3
-
40
-
-
84902494027
-
Role of autophagy in cisplatin resistance in ovarian cancer cells
-
24794870
-
J.Wang, G.S.Wu. Role of autophagy in cisplatin resistance in ovarian cancer cells. J Biol Chem 2014; 289:17163-73; PMID:24794870; http://dx.doi.org/10.1074/jbc.M114.558288
-
(2014)
J Biol Chem
, vol.289
, pp. 17163-17173
-
-
Wang, J.1
Wu, G.S.2
-
41
-
-
0031593675
-
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
-
9639028
-
A.Yamamoto, Y.Tagawa, T.Yoshimori, Y.Moriyama, R.Masaki, Y.Tashiro. Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct Funct 1998; 23:33-42; PMID:9639028; http://dx.doi.org/10.1247/csf.23.33
-
(1998)
Cell Struct Funct
, vol.23
, pp. 33-42
-
-
Yamamoto, A.1
Tagawa, Y.2
Yoshimori, T.3
Moriyama, Y.4
Masaki, R.5
Tashiro, Y.6
-
42
-
-
43049101029
-
Dual-specificity MAP kinase phosphatases (MKPs) and cancer
-
18330678
-
S.M.Keyse. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 2008; 27:253-61; PMID:18330678; http://dx.doi.org/10.1007/s10555-008-9123-1
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 253-261
-
-
Keyse, S.M.1
-
43
-
-
84880331368
-
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
-
23685627
-
R.C.Russell, Y.Tian, H.Yuan, H.W.Park, Y.Y.Chang, J.Kim, H.Kim, T.P.Neufeld, A.Dillin, K.L.Guan. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat Cell Biol 2013; PMID:23685627
-
(2013)
Nat Cell Biol
-
-
Russell, R.C.1
Tian, Y.2
Yuan, H.3
Park, H.W.4
Chang, Y.Y.5
Kim, J.6
Kim, H.7
Neufeld, T.P.8
Dillin, A.9
Guan, K.L.10
-
44
-
-
84856800302
-
Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks
-
22025673
-
S.Alers, A.S.Loffler, S.Wesselborg, B.Stork. Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy:cross talk, shortcuts, and feedbacks. Mol Cell Biol 2012; 32:2-11; PMID:22025673; http://dx.doi.org/10.1128/MCB.06159-11
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2-11
-
-
Alers, S.1
Loffler, A.S.2
Wesselborg, S.3
Stork, B.4
-
45
-
-
84934443098
-
Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy
-
25980607
-
W.Tian, W.Li, Y.Chen, Z.Yan, X.Huang, H.Zhuang, W.Zhong, Y.Chen, W.Wu, C.Lin, et al. Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy. FEBS Lett 2015; 589:1847-54; PMID:25980607; http://dx.doi.org/10.1016/j.febslet.2015.05.020
-
(2015)
FEBS Lett
, vol.589
, pp. 1847-1854
-
-
Tian, W.1
Li, W.2
Chen, Y.3
Yan, Z.4
Huang, X.5
Zhuang, H.6
Zhong, W.7
Chen, Y.8
Wu, W.9
Lin, C.10
-
46
-
-
84883499836
-
Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy
-
23878393
-
A.I.Fogel, B.J.Dlouhy, C.Wang, S.W.Ryu, A.Neutzner, S.A.Hasson, D.P.Sideris, H.Abeliovich, R.J.Youle. Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy. Mol Cell Biol 2013; 33:3675-88; PMID:23878393; http://dx.doi.org/10.1128/MCB.00079-13
-
(2013)
Mol Cell Biol
, vol.33
, pp. 3675-3688
-
-
Fogel, A.I.1
Dlouhy, B.J.2
Wang, C.3
Ryu, S.W.4
Neutzner, A.5
Hasson, S.A.6
Sideris, D.P.7
Abeliovich, H.8
Youle, R.J.9
-
47
-
-
70349916269
-
Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells
-
19755862
-
J.Wang, J.Y.Zhou, L.Zhang, G.S.Wu. Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells. Cell Cycle 2009; 8:3191-8; PMID:19755862; http://dx.doi.org/10.4161/cc.8.19.9751
-
(2009)
Cell Cycle
, vol.8
, pp. 3191-3198
-
-
Wang, J.1
Zhou, J.Y.2
Zhang, L.3
Wu, G.S.4
-
48
-
-
69249153394
-
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
-
19520853
-
J.Wang, M.W.Whiteman, H.Lian, G.Wang, A.Singh, D.Huang, T.Denmark. A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 2009; 284:21412-24; PMID:19520853; http://dx.doi.org/10.1074/jbc.M109.026013
-
(2009)
J Biol Chem
, vol.284
, pp. 21412-21424
-
-
Wang, J.1
Whiteman, M.W.2
Lian, H.3
Wang, G.4
Singh, A.5
Huang, D.6
Denmark, T.7
-
49
-
-
33746166864
-
Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity
-
16818664
-
E.Corcelle, M.Nebout, S.Bekri, N.Gauthier, P.Hofman, P.Poujeol, P.Fenichel, B.Mograbi. Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity. Cancer Res 2006; 66:6861-70; PMID:16818664; http://dx.doi.org/10.1158/0008-5472.CAN-05-3557
-
(2006)
Cancer Res
, vol.66
, pp. 6861-6870
-
-
Corcelle, E.1
Nebout, M.2
Bekri, S.3
Gauthier, N.4
Hofman, P.5
Poujeol, P.6
Fenichel, P.7
Mograbi, B.8
-
50
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
18570871
-
Y.Wei, S.Pattingre, S.Sinha, M.Bassik, B.Levine. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30:678-88; PMID:18570871; http://dx.doi.org/10.1016/j.molcel.2008.06.001
-
(2008)
Mol Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
51
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
21311563
-
R.Kang, H.J.Zeh, M.T.Lotze, D.Tang. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011; 18:571-80; PMID:21311563; http://dx.doi.org/10.1038/cdd.2010.191
-
(2011)
Cell Death Differ
, vol.18
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
52
-
-
84866120470
-
MAPK14/p38alpha confers irinotecan resistance to TP53-defective cells by inducing survival autophagy
-
22647487
-
S.Paillas, A.Causse, L.Marzi, P.de Medina, M.Poirot, V.Denis, N.Vezzio-Vie, L.Espert, H.Arzouk, A.Coquelle, et al. MAPK14/p38alpha confers irinotecan resistance to TP53-defective cells by inducing survival autophagy. Autophagy 2012; 8:1098-112; PMID:22647487; http://dx.doi.org/10.4161/auto.20268
-
(2012)
Autophagy
, vol.8
, pp. 1098-1112
-
-
Paillas, S.1
Causse, A.2
Marzi, L.3
de Medina, P.4
Poirot, M.5
Denis, V.6
Vezzio-Vie, N.7
Espert, L.8
Arzouk, H.9
Coquelle, A.10
-
53
-
-
84872361961
-
Phosphorylation of Atg5 by the Gadd45beta-MEKK4-p38 pathway inhibits autophagy
-
23059785
-
E.Keil, R.Hocker, M.Schuster, F.Essmann, N.Ueffing, B.Hoffman, D.A.Liebermann, K.Pfeffer, K.Schultze-Osthoff, I.Schmitz. Phosphorylation of Atg5 by the Gadd45beta-MEKK4-p38 pathway inhibits autophagy. Cell Death Differ 2013; 20:321-32; PMID:23059785; http://dx.doi.org/10.1038/cdd.2012.129
-
(2013)
Cell Death Differ
, vol.20
, pp. 321-332
-
-
Keil, E.1
Hocker, R.2
Schuster, M.3
Essmann, F.4
Ueffing, N.5
Hoffman, B.6
Liebermann, D.A.7
Pfeffer, K.8
Schultze-Osthoff, K.9
Schmitz, I.10
-
54
-
-
33947418965
-
A novel cell type-specific role of p38alpha in the control of autophagy and cell death in colorectal cancer cells
-
17159917
-
F.Comes, A.Matrone, P.Lastella, B.Nico, F.C.Susca, R.Bagnulo, G.Ingravallo, S.Modica, G.Lo Sasso, A.Moschetta, et al. A novel cell type-specific role of p38alpha in the control of autophagy and cell death in colorectal cancer cells. Cell Death Differ 2007; 14:693-702; PMID:17159917; http://dx.doi.org/10.1038/sj.cdd.4402076
-
(2007)
Cell Death Differ
, vol.14
, pp. 693-702
-
-
Comes, F.1
Matrone, A.2
Lastella, P.3
Nico, B.4
Susca, F.C.5
Bagnulo, R.6
Ingravallo, G.7
Modica, S.8
Lo Sasso, G.9
Moschetta, A.10
-
55
-
-
33846186410
-
Control of the autophagy maturation step by the MAPK ERK and p38: lessons from environmental carcinogens
-
17102581
-
E.Corcelle, N.Djerbi, M.Mari, M.Nebout, C.Fiorini, P.Fenichel, P.Hofman, P.Poujeol, B.Mograbi. Control of the autophagy maturation step by the MAPK ERK and p38:lessons from environmental carcinogens. Autophagy 2007; 3:57-9; PMID:17102581; http://dx.doi.org/10.4161/auto.3424
-
(2007)
Autophagy
, vol.3
, pp. 57-59
-
-
Corcelle, E.1
Djerbi, N.2
Mari, M.3
Nebout, M.4
Fiorini, C.5
Fenichel, P.6
Hofman, P.7
Poujeol, P.8
Mograbi, B.9
-
56
-
-
67749123955
-
Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells
-
19576622
-
P.W.Schlosshauer, W.Li, K.T.Lin, J.L.Chan, L.H.Wang. Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells. Gynecol Oncol 2009; 114:516-22; PMID:19576622; http://dx.doi.org/10.1016/j.ygyno.2009.06.002
-
(2009)
Gynecol Oncol
, vol.114
, pp. 516-522
-
-
Schlosshauer, P.W.1
Li, W.2
Lin, K.T.3
Chan, J.L.4
Wang, L.H.5
-
57
-
-
79960015283
-
Targeting mTOR signaling pathway in ovarian cancer
-
21651485
-
S.Mabuchi, T.Hisamatsu, T.Kimura. Targeting mTOR signaling pathway in ovarian cancer. Curr Med Chem 2011; 18:2960-8; PMID:21651485; http://dx.doi.org/10.2174/092986711796150450
-
(2011)
Curr Med Chem
, vol.18
, pp. 2960-2968
-
-
Mabuchi, S.1
Hisamatsu, T.2
Kimura, T.3
-
58
-
-
0038482086
-
Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells
-
12637505
-
A.Mansouri, L.D.Ridgway, A.L.Korapati, Q.Zhang, L.Tian, Y.Wang, Z.H.Siddik, G.B.Mills, F.X.Claret. Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. J Biol Chem 2003; 278:19245-56; PMID:12637505; http://dx.doi.org/10.1074/jbc.M208134200
-
(2003)
J Biol Chem
, vol.278
, pp. 19245-19256
-
-
Mansouri, A.1
Ridgway, L.D.2
Korapati, A.L.3
Zhang, Q.4
Tian, L.5
Wang, Y.6
Siddik, Z.H.7
Mills, G.B.8
Claret, F.X.9
-
59
-
-
33746364197
-
Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences
-
16714293
-
G.De Chiara, M.E.Marcocci, M.Torcia, M.Lucibello, P.Rosini, P.Bonini, Y.Higashimoto, G.Damonte, A.Armirotti, S.Amodei, et al. Bcl-2 Phosphorylation by p38 MAPK:identification of target sites and biologic consequences. J Biol Chem 2006; 281:21353-61; PMID:16714293; http://dx.doi.org/10.1074/jbc.M511052200
-
(2006)
J Biol Chem
, vol.281
, pp. 21353-21361
-
-
De Chiara, G.1
Marcocci, M.E.2
Torcia, M.3
Lucibello, M.4
Rosini, P.5
Bonini, P.6
Higashimoto, Y.7
Damonte, G.8
Armirotti, A.9
Amodei, S.10
-
60
-
-
0033616709
-
Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis
-
10097113
-
R.K.Srivastava, Q.S.Mi, J.M.Hardwick, D.L.Longo. Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis. Proc Natl Acad Sci U S A 1999; 96:3775-80; PMID:10097113; http://dx.doi.org/10.1073/pnas.96.7.3775
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3775-3780
-
-
Srivastava, R.K.1
Mi, Q.S.2
Hardwick, J.M.3
Longo, D.L.4
-
61
-
-
0038094504
-
Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1)
-
12820963
-
S.Huang, L.Shu, M.B.Dilling, J.Easton, F.C.Harwood, H.Ichijo, P.J.Houghton. Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1). Mol Cell 2003; 11:1491-501; PMID:12820963; http://dx.doi.org/10.1016/S1097-2765(03)00180-1
-
(2003)
Mol Cell
, vol.11
, pp. 1491-1501
-
-
Huang, S.1
Shu, L.2
Dilling, M.B.3
Easton, J.4
Harwood, F.C.5
Ichijo, H.6
Houghton, P.J.7
-
62
-
-
0026760566
-
Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines
-
1638534
-
Y.Yaginuma, H.Westphal. Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines. Cancer Res 1992; 52:4196-9; PMID:1638534
-
(1992)
Cancer Res
, vol.52
, pp. 4196-4199
-
-
Yaginuma, Y.1
Westphal, H.2
-
63
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
8052857
-
S.J.Mansour, W.T.Matten, A.S.Hermann, J.M.Candia, S.Rong, K.Fukasawa, G.F.Wande Woude, N.G.Ahn. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 1994; 265:966-70; PMID:8052857; http://dx.doi.org/10.1126/science.8052857
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
Wande Woude, G.F.7
Ahn, N.G.8
-
64
-
-
33646434223
-
Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer
-
16756719
-
J.Kwong, J.Y.Lee, K.K.Wong, X.Zhou, D.T.Wong, K.W.Lo, W.R.Welch, R.S.Berkowitz, S.C.Mok. Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer. Neoplasia 2006; 8:268-78; PMID:16756719; http://dx.doi.org/10.1593/neo.05502
-
(2006)
Neoplasia
, vol.8
, pp. 268-278
-
-
Kwong, J.1
Lee, J.Y.2
Wong, K.K.3
Zhou, X.4
Wong, D.T.5
Lo, K.W.6
Welch, W.R.7
Berkowitz, R.S.8
Mok, S.C.9
-
65
-
-
33646416743
-
The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death
-
16651445
-
J.Y.Zhou, Y.Liu, G.S.Wu. The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death. Cancer Res 2006; 66:4888-94; PMID:16651445; http://dx.doi.org/10.1158/0008-5472.CAN-05-4229
-
(2006)
Cancer Res
, vol.66
, pp. 4888-4894
-
-
Zhou, J.Y.1
Liu, Y.2
Wu, G.S.3
|