Endothelial Cell Inflammatory Reactions Are Altered in the Presence of E-Cigarette Extracts of Variable Nicotine

Cellular and Molecular Bioengineering

Volumn 10, Issue 1, 2017, Pages 124-133

  Barber, Kirstin E ^a   Ghebrehiwet, Berhane ^b   Yin, Wei ^a   Rubenstein, David A ^a  

^a St Francis Hospital The Heart Center   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Cardiovascular diseases; Cardiovascular risk factors; Complement; Electronic cigarettes

Indexed keywords

COMPLEMENT COMPONENT C1Q; NICOTINE; TOBACCO SMOKE;

ARTICLE; CARDIOVASCULAR DISEASE; CELL DENSITY; CELL PROLIFERATION; CELL VIABILITY; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; CONTROLLED STUDY; ELECTRONIC CIGARETTE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; METABOLIC ACTIVATION; PARTICULATE MATTER; PROTEIN EXPRESSION; RISK FACTOR; TOBACCO; VASCULITIS;

EID: 84983414167     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-016-0465-4     Document Type: Article

References (29)

1. Benowitz, N. L., F. Kuyt, and P. Jacob, 3rd. Influence of nicotine on cardiovascular and hormonal effects of cigarette smoking. Clin. Pharmacol. Ther. 36:74–81, 1984.
2. Cucina, A., V. Corvino, P. Sapienza, V. Borrelli, M. Lucarelli, S. Scarpa, R. Strom, L. Santoro-D’Angelo, and A. Cavallaro. Nicotine regulates basic fibroblastic growth factor and transforming growth factor beta1 production in endothelial cells. Biochem. Biophys. Res. Commun. 257:306–312, 1999.
3. Czogala, J., M. L. Goniewicz, B. Fidelus, W. Zielinska-Danch, M. J. Travers, and A. Sobczak. Secondhand exposure to vapors from electronic cigarettes. Nicotine Tob. Res. 16:655–662, 2014.
4. Fuoco, F. C., G. Buonanno, L. Stabile, and P. Vigo. Influential parameters on particle concentration and size distribution in the mainstream of e-cigarettes. Environ. Pollut. 184:523–529, 2014.
5. Ghebrehiwet, B., J. Jesty, and E. I. Peerschke. Gc1q-r/p33: structure-function predictions from the crystal structure. Immunobiology 205:421–432, 2002.
6. Ghebrehiwet, B., and E. I. Peerschke. Cc1q-r (calreticulin) and gc1q-r/p33: ubiquitously expressed multi-ligand binding cellular proteins involved in inflammation and infection. Mol. Immunol. 41:173–183, 2004.
7. Goniewicz, M. L., J. Knysak, M. Gawron, L. Kosmider, A. Sobczak, J. Kurek, A. Prokopowicz, M. Jablonska-Czapla, C. Rosik-Dulewska, C. Havel, P. Jacob, 3rd, and N. Benowitz. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob. Control 23:133–139, 2014.
8. Guarino, F., G. Cantarella, M. Caruso, C. Russo, S. Mancuso, G. Arcidiacono, R. R. Cacciola, R. Bernardini, and R. Polosa. Endothelial activation and injury by cigarette smoke exposure. J. Biol. Regul. Homeost. Agents 25:259–268, 2011.
9. Hom, S., L. Chen, T. Wang, B. Ghebrehiwet, W. Yin, and D. A. Rubenstein. Platelet activation, adhesion, inflammation and aggregation potential are altered in the presence of electronic cigarette extracts of variable nicotine concentration. Platelets in press.
10. Maria, Z., W. Yin, and D. A. Rubenstein. Glycated albumin and pathological shear stress alters endothelial cell thrombogenic potential, pro-inflammatory state and cytoskeletal dynamics. J. Diabetes Metab. S4:003, 2011.
11. Maria, Z., W. Yin, and D. A. Rubenstein. Combined effects of physiologically relevant disturbed wall shear stress and glycated albumin on endothelial cell functions associated with inflammation, thrombosis and cytoskeletal dynamics. J. Diabetes Investig. 5:372–381, 2014.
12. Morris, P. B., B. A. Ference, E. Jahangir, D. N. Feldman, J. J. Ryan, H. Bahrami, M. F. El-Chami, S. Bhakta, D. E. Winchester, M. H. Al-Mallah, M. S. Shields, P. Deedwania, L. S. Mehta, B. A. Phan, and N. L. Benowitz. Cardiovascular effects of exposure to cigarette smoke and electronic cigarettes: clinical perspectives from the prevention of cardiovascular disease section leadership council and early career councils of the American College of Cardiology. J. Am. Coll. Cardiol. 66:1378–1391, 2015.
13. Patil, A. J., A. L. Gramajo, A. Sharma, G. M. Seigel, B. D. Kuppermann, and M. C. Kenney. Differential effects of nicotine on retinal and vascular cells in vitro. Toxicology 259:69–76, 2009.
14. Peerschke, E. I., A. S. Bayer, B. Ghebrehiwet, and Y. Q. Xiong. Gc1qr/p33 blockade reduces staphylococcus aureus colonization of target tissues in an animal model of infective endocarditis. Infect. Immun. 74:4418–4423, 2006.
15. Peerschke, E. I., J. O. Minta, S. Z. Zhou, A. Bini, A. Gotlieb, R. W. Colman, and B. Ghebrehiwet. Expression of gc1q-r/p33 and its major ligands in human atherosclerotic lesions. Mol. Immunol. 41:759–766, 2004.
16. Peerschke, E. I., W. Yin, and B. Ghebrehiwet. Platelet mediated complement activation. Adv. Exp. Med. Biol. 632:81–91, 2008.
17. Pereira, I. A., and E. F. Borba. The role of inflammation, humoral and cell mediated autoimmunity in the pathogenesis of atherosclerosis. Swiss Med. Wkly. 138:534–539, 2008.
18. Robbins, R. A., K. J. Nelson, G. L. Gossman, S. Koyama, and S. I. Rennard. Complement activation by cigarette smoke. Am. J. Physiol. 260:L254–L259, 1991.
19. Rubenstein, D., D. Han, S. Goldgraben, H. El-Gendi, P. I. Gouma, and M. D. Frame. Bioassay chamber for angiogenesis with perfused explanted arteries and electrospun scaffolding. Microcirculation 14:723–737, 2007.
20. Rubenstein, D. A., S. Hom, B. Ghebrehiwet, and W. Yin. Tobacco and e-cigarette products initiate kupffer cell inflammatory responses. Mol. Immunol. 67:652–660, 2015.
21. Rubenstein, D., J. Jesty, and D. Bluestein. Differences between mainstream and sidestream cigarette smoke extracts and nicotine in the activation of platelets under static and flow conditions. Circulation 109:78–83, 2004.
22. Rubenstein, D. A., B. E. Morton, and W. Yin. The combined effects of sidestream smoke extracts and glycated serum albumin on endothelial cells and platelets. Cardiovasc. Diabetol. 9:28, 2010.
23. Schmitt, M. M., L. Fraemohs, T. M. Hackeng, C. Weber, and R. R. Koenen. Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-a redistribution. Atherosclerosis 234:254–264, 2014.
24. Schulte, D. J., A. Yilmaz, K. Shimada, M. C. Fishbein, E. L. Lowe, S. Chen, M. Wong, T. M. Doherty, T. Lehman, T. R. Crother, R. Sorrentino, and M. Arditi. Involvement of innate and adaptive immunity in a murine model of coronary arteritis mimicking kawasaki disease. J. Immunol. 183:5311–5318, 2009.
25. Yang, Y. M., and G. T. Liu. Damaging effect of cigarette smoke extract on primary cultured human umbilical vein endothelial cells and its mechanism. Biomed. Environ. Sci. 17:121–134, 2004.
26. Yin, W., B. Ghebrehiwet, B. Weksler, and E. I. Peerschke. Regulated complement deposition on the surface of human endothelial cells: effect of tobacco smoke and shear stress. Thromb. Res. 122:221–228, 2008.
27. Yin, W., E. C. Ngwe, B. Ghebrehiwet, and D. A. Rubenstein. The combined effect of sidestream smoke and dynamic shear stress on endothelial cell inflammatory responses. Thromb. Res. 135:362–367, 2015.
28. Yin, W., and D. A. Rubenstein. Dose effect of shear stress on platelet complement activation in a cone and plate shearing device. Cell. Mol. Bioeng. 2:274–280, 2009.
29. Yin, W., and D. A. Rubenstein. Differences between mainstream and sidestream tobacco smoke extracts and nicotine in the activation and aggregation of platelets subjected to cardiovascular conditions in diabetes. Diabetes Vasc. Dis. Res. 10:57–64, 2013.