Safe and sensitive antiviral screening platform based on recombinant human coronavirus OC43 expressing the luciferase reporter gene

Antimicrobial Agents and Chemotherapy

Volumn 60, Issue 9, 2016, Pages 5492-5503

  Shen, Liang ^a   Yang, Yang ^a   Ye, Fei ^a   Liu, Gaoshan ^a   Desforges, Marc ^b   Talbot, Pierre J ^b   Tan, Wenjie ^a  

^a BEIJING HOSPITAL   (China)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; DEAD BOX PROTEIN; HOST FACTOR; NONSTRUCTURAL PROTEIN 2; PROTEIN KINASE R; RENILLA LUCIFERIN 2 MONOOXYGENASE; RIBAVIRIN; SMALL INTERFERING RNA; ANTIVIRUS AGENT; LUCIFERASE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; BHK CELL LINE; CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC STABILITY; HIGH THROUGHPUT SCREENING; HUMAN CORONAVIRUS OC43; IC50; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPORTER GENE; VIROGENESIS; VIRUS RECOMBINANT; VIRUS REPLICATION; WILD TYPE; CELL LINE; CORONAVIRUS INFECTIONS; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; HUMAN; RESPIRATORY TRACT INFECTIONS; VIROLOGY;

ANTIVIRAL AGENTS; CELL LINE; CHLOROQUINE; CORONAVIRUS INFECTIONS; CORONAVIRUS OC43, HUMAN; GENES, REPORTER; HEK293 CELLS; HUMANS; LUCIFERASES; RESPIRATORY TRACT INFECTIONS; RIBAVIRIN; VIRUS REPLICATION;

EID: 84983252172     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00814-16     Document Type: Article

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