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Volumn 28, Issue 4, 2015, Pages 236-245

Immunoconjugates in the management of hairy cell leukemia

Author keywords

BL22; CD22; CD25; Moxetumomab pasudotox; Pseudomonas exotoxin; Recombinant immunotoxin

Indexed keywords

ANTIBODY CONJUGATE; CD22 ANTIGEN; IMMUNOTOXIN; IMMUNOTOXIN BL22; IMMUNOTOXIN LMB2; MOXETUMOMAB PASUDOTOX; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; B RAF KINASE; B3(FV)-PE38KDEL RECOMBINANT IMMUNOTOXIN; BACTERIAL TOXIN; BRAF PROTEIN, HUMAN; CLADRIBINE; ELONGATION FACTOR 2; EXOTOXIN; MONOCLONAL ANTIBODY; PENTOSTATIN;

EID: 84983174913     PISSN: 15216926     EISSN: 15321924     Source Type: Journal    
DOI: 10.1016/j.beha.2015.09.003     Document Type: Review
Times cited : (27)

References (79)
  • 3
    • 0028929938 scopus 로고
    • Randomized comparison of pentostatin versus interferon alfa-2a in previously untreated patients with hairy cell leukemia: An intergroup study
    • M. Grever, K. Kopecky, M.K. Foucar, D. Head, J.M. Bennett, R.E. Hutchison, and et al. Randomized comparison of pentostatin versus interferon alfa-2a in previously untreated patients with hairy cell leukemia: an intergroup study J Clin Oncol 13 1995 974 982
    • (1995) J Clin Oncol , vol.13 , pp. 974-982
    • Grever, M.1    Kopecky, K.2    Foucar, M.K.3    Head, D.4    Bennett, J.M.5    Hutchison, R.E.6
  • 6
    • 0019120145 scopus 로고
    • A chronic lymphoproliferative disorder with distinctive features: A distinct variant of hairy-cell leukaemia
    • J.C. Cawley, G.F. Burns, and F.G. Hayhoe A chronic lymphoproliferative disorder with distinctive features: a distinct variant of hairy-cell leukaemia Leuk Res 4 1980 547 559
    • (1980) Leuk Res , vol.4 , pp. 547-559
    • Cawley, J.C.1    Burns, G.F.2    Hayhoe, F.G.3
  • 7
    • 78649893951 scopus 로고    scopus 로고
    • Hairy-cell leukemia variant: Recent view on diagnosis, biology and treatment
    • T. Robak Hairy-cell leukemia variant: recent view on diagnosis, biology and treatment Cancer Treat Rev 37 2011 3 10
    • (2011) Cancer Treat Rev , vol.37 , pp. 3-10
    • Robak, T.1
  • 9
    • 33748593104 scopus 로고    scopus 로고
    • Immunophenotyping and differential diagnosis of hairy cell leukemia
    • E. Matutes Immunophenotyping and differential diagnosis of hairy cell leukemia Hematol Oncol Clin North Am 20 2006 1051 1063
    • (2006) Hematol Oncol Clin North Am , vol.20 , pp. 1051-1063
    • Matutes, E.1
  • 15
    • 0032530684 scopus 로고    scopus 로고
    • Long-term follow-up of patients with hairy cell leukemia after cladribine treatment
    • A. Saven, C. Burian, J.A. Koziol, and L.D. Piro Long-term follow-up of patients with hairy cell leukemia after cladribine treatment Blood 92 1998 1918 1926
    • (1998) Blood , vol.92 , pp. 1918-1926
    • Saven, A.1    Burian, C.2    Koziol, J.A.3    Piro, L.D.4
  • 17
    • 22044444135 scopus 로고    scopus 로고
    • Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): Long-term follow-up of the Northwestern university experience
    • P. Chadha, A.W. Rademaker, P. Mendiratta, B. Kim, D.M. Evanchuk, D. Hakimian, and et al. Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): long-term follow-up of the Northwestern university experience Blood 106 2005 241 246
    • (2005) Blood , vol.106 , pp. 241-246
    • Chadha, P.1    Rademaker, A.W.2    Mendiratta, P.3    Kim, B.4    Evanchuk, D.M.5    Hakimian, D.6
  • 18
    • 0025274664 scopus 로고
    • Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine
    • L.D. Piro, C.J. Carrera, D.A. Carson, and E. Beutler Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine N Engl J Med 322 1990 1117 1121
    • (1990) N Engl J Med , vol.322 , pp. 1117-1121
    • Piro, L.D.1    Carrera, C.J.2    Carson, D.A.3    Beutler, E.4
  • 20
    • 0037362951 scopus 로고    scopus 로고
    • Extended follow-up of patients with hairy cell leukemia after treatment with cladribine
    • G.R. Goodman, C. Burian, J.A. Koziol, and A. Saven Extended follow-up of patients with hairy cell leukemia after treatment with cladribine J Clin Oncol 21 2003 891 896
    • (2003) J Clin Oncol , vol.21 , pp. 891-896
    • Goodman, G.R.1    Burian, C.2    Koziol, J.A.3    Saven, A.4
  • 21
    • 66749169284 scopus 로고    scopus 로고
    • Long-term follow-up of 233 patients with hairy cell leukaemia, treated initially with pentostatin or cladribine, at a median of 16 years from diagnosis
    • M. Else, C.E. Dearden, E. Matutes, J. Garcia-Talavera, A.Z. Rohatiner, S.A. Johnson, and et al. Long-term follow-up of 233 patients with hairy cell leukaemia, treated initially with pentostatin or cladribine, at a median of 16 years from diagnosis Br J Haematol 145 2009 733 740
    • (2009) Br J Haematol , vol.145 , pp. 733-740
    • Else, M.1    Dearden, C.E.2    Matutes, E.3    Garcia-Talavera, J.4    Rohatiner, A.Z.5    Johnson, S.A.6
  • 22
    • 0034329819 scopus 로고    scopus 로고
    • Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin
    • I.W. Flinn, K.J. Kopecky, M.K. Foucar, D. Head, J.M. Bennett, R. Huchison, and et al. Long-term follow-up of remission duration, mortality, and second malignancies in hairy cell leukemia patients treated with pentostatin Blood 96 2000 2981 2986
    • (2000) Blood , vol.96 , pp. 2981-2986
    • Flinn, I.W.1    Kopecky, K.J.2    Foucar, M.K.3    Head, D.4    Bennett, J.M.5    Huchison, R.6
  • 23
    • 84892637595 scopus 로고    scopus 로고
    • Clinical characteristics and long-term outcome of young hairy cell leukemia patients treated with cladribine: A single-institution series
    • J.D. Rosenberg, C. Burian, J. Waalen, and A. Saven Clinical characteristics and long-term outcome of young hairy cell leukemia patients treated with cladribine: a single-institution series Blood 123 2014 177 183
    • (2014) Blood , vol.123 , pp. 177-183
    • Rosenberg, J.D.1    Burian, C.2    Waalen, J.3    Saven, A.4
  • 24
    • 0032518239 scopus 로고    scopus 로고
    • Autonomic neuropathy in transgenic mice caused by immunotoxin targeting of the peripheral nervous system
    • H. Sawada, K. Nishii, T. Suzuki, K. Hasegawa, T. Hata, I. Nagatsu, and et al. Autonomic neuropathy in transgenic mice caused by immunotoxin targeting of the peripheral nervous system J Neurosci Res 51 1998 162 173
    • (1998) J Neurosci Res , vol.51 , pp. 162-173
    • Sawada, H.1    Nishii, K.2    Suzuki, T.3    Hasegawa, K.4    Hata, T.5    Nagatsu, I.6
  • 26
    • 0023320367 scopus 로고
    • Consensus resolution: Proposed criteria for evaluation of response to treatment in hairy cell leukemia
    • Consensus resolution: proposed criteria for evaluation of response to treatment in hairy cell leukemia Leukemia 1 1987 405
    • (1987) Leukemia , vol.1 , pp. 405
  • 27
    • 0031670669 scopus 로고    scopus 로고
    • Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine via the group C protocol mechanism of the National Cancer Institute: A report of 979 patients
    • B.D. Cheson, J.M. Sorensen, D.A. Vena, M.J. Montello, J.A. Barrett, E. Damasio, and et al. Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine via the group C protocol mechanism of the National Cancer Institute: a report of 979 patients J Clin Oncol 16 1998 3007 3015
    • (1998) J Clin Oncol , vol.16 , pp. 3007-3015
    • Cheson, B.D.1    Sorensen, J.M.2    Vena, D.A.3    Montello, M.J.4    Barrett, J.A.5    Damasio, E.6
  • 29
    • 0034001076 scopus 로고    scopus 로고
    • Phase i trial of recombinant immunotoxin Anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies
    • R.J. Kreitman, W.H. Wilson, J.D. White, M. Stetler-Stevenson, E.S. Jaffe, T.A. Waldmann, and et al. Phase I trial of recombinant immunotoxin Anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies J Clin Oncol 18 2000 1614 1636
    • (2000) J Clin Oncol , vol.18 , pp. 1614-1636
    • Kreitman, R.J.1    Wilson, W.H.2    White, J.D.3    Stetler-Stevenson, M.4    Jaffe, E.S.5    Waldmann, T.A.6
  • 30
  • 32
    • 84861542159 scopus 로고    scopus 로고
    • Phase i trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia
    • R.J. Kreitman, M.S. Tallman, T. Robak, S. Coutre, W.H. Wilson, M. Stetler-Stevenson, and et al. Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia J Clin Oncol 30 2012 1822 1828
    • (2012) J Clin Oncol , vol.30 , pp. 1822-1828
    • Kreitman, R.J.1    Tallman, M.S.2    Robak, T.3    Coutre, S.4    Wilson, W.H.5    Stetler-Stevenson, M.6
  • 33
    • 84890753551 scopus 로고    scopus 로고
    • Cladribine with immediate rituximab for the treatment of patients with variant hairy cell leukemia
    • R.J. Kreitman, W. Wilson, K.R. Calvo, E. Arons, L. Roth, J. Sapolsky, and et al. Cladribine with immediate rituximab for the treatment of patients with variant hairy cell leukemia Clin Cancer Res 19 2013 6873 6881
    • (2013) Clin Cancer Res , vol.19 , pp. 6873-6881
    • Kreitman, R.J.1    Wilson, W.2    Calvo, K.R.3    Arons, E.4    Roth, L.5    Sapolsky, J.6
  • 35
    • 33646719675 scopus 로고    scopus 로고
    • Minimal residual disease in hairy cell leukemia patients assessed by clone-specific polymerase chain reaction
    • E. Arons, I. Margulies, L. Sorbara, M. Raffeld, M. Stetler-Stevenson, I. Pastan, and et al. Minimal residual disease in hairy cell leukemia patients assessed by clone-specific polymerase chain reaction Clin Cancer Res 12 2006 2804 2811
    • (2006) Clin Cancer Res , vol.12 , pp. 2804-2811
    • Arons, E.1    Margulies, I.2    Sorbara, L.3    Raffeld, M.4    Stetler-Stevenson, M.5    Pastan, I.6
  • 36
    • 0021231875 scopus 로고
    • Pseudomonas exotoxin-Anti-Tac: Cell specific immunotoxin active against cells expressing the human T cell growth factor receptor
    • D.J.P. FitzGerald, T.A. Waldmann, M.C. Willingham, and I. Pastan Pseudomonas exotoxin-Anti-Tac: cell specific immunotoxin active against cells expressing the human T cell growth factor receptor J Clin Invest 74 1984 966 971
    • (1984) J Clin Invest , vol.74 , pp. 966-971
    • FitzGerald, D.J.P.1    Waldmann, T.A.2    Willingham, M.C.3    Pastan, I.4
  • 39
    • 0018167496 scopus 로고
    • One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
    • M. Yamaizumi, E. Mekada, T. Uchida, and Y. Okada One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell Cell 15 1978 245 250
    • (1978) Cell , vol.15 , pp. 245-250
    • Yamaizumi, M.1    Mekada, E.2    Uchida, T.3    Okada, Y.4
  • 40
    • 0023664263 scopus 로고
    • The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes
    • Y. Endo, K. Mitsui, M. Motizuki, and K. Tsurugi The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes J Biol Chem 262 1987 5908 5912
    • (1987) J Biol Chem , vol.262 , pp. 5908-5912
    • Endo, Y.1    Mitsui, K.2    Motizuki, M.3    Tsurugi, K.4
  • 41
    • 0023664604 scopus 로고
    • Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin
    • S.F. Carroll, and R.J. Collier Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin J Biol Chem 262 1987 8707 8711
    • (1987) J Biol Chem , vol.262 , pp. 8707-8711
    • Carroll, S.F.1    Collier, R.J.2
  • 42
    • 0019333247 scopus 로고
    • ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products
    • 10717-01720
    • B.G. Van Ness, J.B. Howard, and J.W. Bodley ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products J Biol Chem 255 1980 10717-01720
    • (1980) J Biol Chem , vol.255
    • Van Ness, B.G.1    Howard, J.B.2    Bodley, J.W.3
  • 43
    • 0024121599 scopus 로고
    • Cytotoxic activity of an interleukin 2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli
    • H. Lorberboum-Galski, D. FitzGerald, V. Chaudhary, S. Adhya, and I. Pastan Cytotoxic activity of an interleukin 2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli Proc Natl Acad Sci U. S. A 85 1988 1922 1926
    • (1988) Proc Natl Acad Sci U. S. A , vol.85 , pp. 1922-1926
    • Lorberboum-Galski, H.1    FitzGerald, D.2    Chaudhary, V.3    Adhya, S.4    Pastan, I.5
  • 45
    • 0030830611 scopus 로고    scopus 로고
    • Getting plant toxins to fuse
    • R.J. Kreitman Getting plant toxins to fuse Leuk Res 21 1997 997 999
    • (1997) Leuk Res , vol.21 , pp. 997-999
    • Kreitman, R.J.1
  • 46
    • 0024349836 scopus 로고
    • A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin
    • V.K. Chaudhary, C. Queen, R.P. Junghans, T.A. Waldmann, D.J. FitzGerald, and I. Pastan A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin Nature 339 1989 394 397
    • (1989) Nature , vol.339 , pp. 394-397
    • Chaudhary, V.K.1    Queen, C.2    Junghans, R.P.3    Waldmann, T.A.4    FitzGerald, D.J.5    Pastan, I.6
  • 47
    • 51049120495 scopus 로고    scopus 로고
    • Differential cellular internalization of anti-CD19 and-CD22 immunotoxins results in different cytotoxic activity
    • X. Du, R. Beers, D.J. FitzGerald, and I. Pastan Differential cellular internalization of anti-CD19 and-CD22 immunotoxins results in different cytotoxic activity Cancer Res 68 2008 6300 6305
    • (2008) Cancer Res , vol.68 , pp. 6300-6305
    • Du, X.1    Beers, R.2    FitzGerald, D.J.3    Pastan, I.4
  • 48
    • 0026455183 scopus 로고
    • 280 generates the enzymatically active fragment which translocates to the cytosol
    • 280 generates the enzymatically active fragment which translocates to the cytosol J Biol Chem 267 1992 25396 25401
    • (1992) J Biol Chem , vol.267 , pp. 25396-25401
    • Ogata, M.1    Fryling, C.M.2    Pastan, I.3    FitzGerald, D.J.4
  • 49
    • 0026353962 scopus 로고
    • Characterization of a cellular protease that cleaves Pseudomonas exotoxin
    • C. Fryling, M. Ogata, and D. FitzGerald Characterization of a cellular protease that cleaves Pseudomonas exotoxin Infect Immun 60 1992 497 502
    • (1992) Infect Immun , vol.60 , pp. 497-502
    • Fryling, C.1    Ogata, M.2    FitzGerald, D.3
  • 50
    • 0028304478 scopus 로고
    • Cleavage of Pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver
    • M.F. Chiron, C.M. Fryling, and D.J. FitzGerald Cleavage of Pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver J Biol Chem 269 1994 18167 18176
    • (1994) J Biol Chem , vol.269 , pp. 18167-18176
    • Chiron, M.F.1    Fryling, C.M.2    FitzGerald, D.J.3
  • 51
    • 0033554871 scopus 로고    scopus 로고
    • Reduction of furin-nicked Pseudomonas exotoxin A: An unfolding story
    • M.L. McKee, and D.J. FitzGerald Reduction of furin-nicked Pseudomonas exotoxin A: an unfolding story Biochemistry 38 1999 16507 16513
    • (1999) Biochemistry , vol.38 , pp. 16507-16513
    • McKee, M.L.1    FitzGerald, D.J.2
  • 52
    • 0028951457 scopus 로고
    • Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor
    • R.J. Kreitman, and I. Pastan Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor Biochem J 307 1995 29 37
    • (1995) Biochem J , vol.307 , pp. 29-37
    • Kreitman, R.J.1    Pastan, I.2
  • 53
    • 0028225440 scopus 로고
    • Domain II of Pseudomonas exotoxin A arrests the transfer of translocating nascent chains into mammalian microsomes
    • C. Theuer, S. Kasturi, and I. Pastan Domain II of Pseudomonas exotoxin A arrests the transfer of translocating nascent chains into mammalian microsomes Biochemistry 33 1994 5894 5900
    • (1994) Biochemistry , vol.33 , pp. 5894-5900
    • Theuer, C.1    Kasturi, S.2    Pastan, I.3
  • 54
    • 0027317269 scopus 로고
    • The N-terminal region of the 37-kDa translocated fragment of Pseudomonas exotoxin A aborts translocation by promoting its own export after microsomal membrane insertion
    • C.P. Theuer, J. Buchner, D. FitzGerald, and I. Pastan The N-terminal region of the 37-kDa translocated fragment of Pseudomonas exotoxin A aborts translocation by promoting its own export after microsomal membrane insertion Proc Natl Acad Sci U. S. A. 90 1993 7774 7778
    • (1993) Proc Natl Acad Sci U. S. A. , vol.90 , pp. 7774-7778
    • Theuer, C.P.1    Buchner, J.2    FitzGerald, D.3    Pastan, I.4
  • 55
    • 55449100858 scopus 로고    scopus 로고
    • Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development
    • T.R. Webb, S.H. Cross, L. McKie, R. Edgar, L. Vizor, J. Harrison, and et al. Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development J Cell Sci 121 2008 3140 3145
    • (2008) J Cell Sci , vol.121 , pp. 3140-3145
    • Webb, T.R.1    Cross, S.H.2    McKie, L.3    Edgar, R.4    Vizor, L.5    Harrison, J.6
  • 56
    • 0028889656 scopus 로고
    • Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1
    • U. Brinkmann, E. Brinkmann, M. Gallo, and I. Pastan Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1 Proc Natl Acad Sci U. S. A. 92 1995 10427 10431
    • (1995) Proc Natl Acad Sci U. S. A. , vol.92 , pp. 10427-10431
    • Brinkmann, U.1    Brinkmann, E.2    Gallo, M.3    Pastan, I.4
  • 57
    • 0034119870 scopus 로고    scopus 로고
    • Apoptosis induced by immunotoxins used in the treatment of hematologic malignancies
    • I.J.C. Keppler-Hafkemeyer, R.J. Kreitman, and I. Pastan Apoptosis induced by immunotoxins used in the treatment of hematologic malignancies Int J Cancer 87 2000 86 94
    • (2000) Int J Cancer , vol.87 , pp. 86-94
    • Keppler-Hafkemeyer, I.J.C.1    Kreitman, R.J.2    Pastan, I.3
  • 58
    • 1642345125 scopus 로고    scopus 로고
    • Induction of caspase-dependent programmed cell death in B-cell chronic lymphocytic leukemia cells by anti-CD22 immunotoxins
    • T. Decker, M. Oelsner, R.J. Kreitman, G. Salvatore, Q.C. Wang, I. Pastan, and et al. Induction of caspase-dependent programmed cell death in B-cell chronic lymphocytic leukemia cells by anti-CD22 immunotoxins Blood 103 2004 2718 2726
    • (2004) Blood , vol.103 , pp. 2718-2726
    • Decker, T.1    Oelsner, M.2    Kreitman, R.J.3    Salvatore, G.4    Wang, Q.C.5    Pastan, I.6
  • 59
    • 77954361875 scopus 로고    scopus 로고
    • Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1
    • X. Du, R.J. Youle, D.J. FitzGerald, and I. Pastan Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1 Mol Cell Biol 30 2010 3444 3452
    • (2010) Mol Cell Biol , vol.30 , pp. 3444-3452
    • Du, X.1    Youle, R.J.2    FitzGerald, D.J.3    Pastan, I.4
  • 60
    • 0027572639 scopus 로고
    • Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: Relative importance of the two toxin disulfide bonds
    • R.J. Kreitman, J.K. Batra, S. Seetharam, V.K. Chaudhary, D.J. FitzGerald, and I. Pastan Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds Bioconj Chem 4 1993 112 120
    • (1993) Bioconj Chem , vol.4 , pp. 112-120
    • Kreitman, R.J.1    Batra, J.K.2    Seetharam, S.3    Chaudhary, V.K.4    FitzGerald, D.J.5    Pastan, I.6
  • 61
    • 0026806808 scopus 로고
    • Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia
    • R.J. Kreitman, V.K. Chaudhary, R.W. Kozak, D.J.P. FitzGerald, T.A. Waldmann, and I. Pastan Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia Blood 80 1992 2344 2352
    • (1992) Blood , vol.80 , pp. 2344-2352
    • Kreitman, R.J.1    Chaudhary, V.K.2    Kozak, R.W.3    FitzGerald, D.J.P.4    Waldmann, T.A.5    Pastan, I.6
  • 62
    • 0027223468 scopus 로고
    • Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia
    • R.J. Kreitman, V.K. Chaudhary, T.A. Waldmann, B. Hanchard, B. Cranston, D.J.P. FitzGerald, and et al. Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia Leukemia 7 1993 553 562
    • (1993) Leukemia , vol.7 , pp. 553-562
    • Kreitman, R.J.1    Chaudhary, V.K.2    Waldmann, T.A.3    Hanchard, B.4    Cranston, B.5    FitzGerald, D.J.P.6
  • 63
    • 0028330865 scopus 로고
    • Cytotoxicity of recombinant Fab and Fv immunotoxins on adult T-cell leukemia lymph node and blood cells in the presence of soluble interleukin-2 receptor
    • T. Saito, R.J. Kreitman, S-i. Hanada, T. Makino, A. Utsunomiya, T. Sumizawa, and et al. Cytotoxicity of recombinant Fab and Fv immunotoxins on adult T-cell leukemia lymph node and blood cells in the presence of soluble interleukin-2 receptor Cancer Res 54 1994 1059 1064
    • (1994) Cancer Res , vol.54 , pp. 1059-1064
    • Saito, T.1    Kreitman, R.J.2    Hanada, S.-I.3    Makino, T.4    Utsunomiya, A.5    Sumizawa, T.6
  • 64
    • 0033963828 scopus 로고    scopus 로고
    • Hairy cell leukemia, a B-cell neoplasm which is particularly sensitive to the cytotoxic effect of anti-Tac(Fv)-PE38 (LMB-2)
    • D.H. Robbins, I. Margulies, M. Stetler-Stevenson, and R.J. Kreitman Hairy cell leukemia, a B-cell neoplasm which is particularly sensitive to the cytotoxic effect of anti-Tac(Fv)-PE38 (LMB-2) Clin Cancer Res 6 2000 693 700
    • (2000) Clin Cancer Res , vol.6 , pp. 693-700
    • Robbins, D.H.1    Margulies, I.2    Stetler-Stevenson, M.3    Kreitman, R.J.4
  • 65
    • 0028867234 scopus 로고
    • Diagnostic relevance of peripheral blood immunocytochemistry in hairy cell leukaemia
    • I. Cordone, L. Annino, S. Masi, E. Pescarmona, S. Rahimi, A. Ferrari, and et al. Diagnostic relevance of peripheral blood immunocytochemistry in hairy cell leukaemia J Clin Pathol 48 1995 955 960
    • (1995) J Clin Pathol , vol.48 , pp. 955-960
    • Cordone, I.1    Annino, L.2    Masi, S.3    Pescarmona, E.4    Rahimi, S.5    Ferrari, A.6
  • 66
    • 0027247855 scopus 로고
    • Diagnostic application of two-color flow cytometry in 161 cases of hairy cell leukemia
    • B.A. Robbins, D.J. Ellison, J.C. Spinosa, C.A. Carey, R.J. Lukes, S. Poppema, and et al. Diagnostic application of two-color flow cytometry in 161 cases of hairy cell leukemia Blood 82 1993 1277 1287
    • (1993) Blood , vol.82 , pp. 1277-1287
    • Robbins, B.A.1    Ellison, D.J.2    Spinosa, J.C.3    Carey, C.A.4    Lukes, R.J.5    Poppema, S.6
  • 67
    • 0027407178 scopus 로고
    • Pseudomonas exotoxin-based immunotoxins containing the antibody LL2 or LL2-Fab' induce regression of subcutaneous human B-cell lymphoma in mice
    • R.J. Kreitman, H.J. Hansen, A.L. Jones, D.J.P. FitzGerald, D.M. Goldenberg, and I. Pastan Pseudomonas exotoxin-based immunotoxins containing the antibody LL2 or LL2-Fab' induce regression of subcutaneous human B-cell lymphoma in mice Cancer Res 53 1993 819 825
    • (1993) Cancer Res , vol.53 , pp. 819-825
    • Kreitman, R.J.1    Hansen, H.J.2    Jones, A.L.3    FitzGerald, D.J.P.4    Goldenberg, D.M.5    Pastan, I.6
  • 68
    • 0030250422 scopus 로고    scopus 로고
    • Characterization of RFB4-Pseudomonas exotoxin A immunotoxins targeted to CD22 on B-cell malignancies
    • E. Mansfield, I. Pastan, and D.J. FitzGerald Characterization of RFB4-Pseudomonas exotoxin A immunotoxins targeted to CD22 on B-cell malignancies Bioconj Chem 7 1996 557 563
    • (1996) Bioconj Chem , vol.7 , pp. 557-563
    • Mansfield, E.1    Pastan, I.2    FitzGerald, D.J.3
  • 69
    • 0030975823 scopus 로고    scopus 로고
    • Recombinant RFB4 single-chain immunotoxin that is cytotoxic towards CD22-positive cells
    • E. Mansfield, M.F. Chiron, P. Amlot, I. Pastan, and D.J. FitzGerald Recombinant RFB4 single-chain immunotoxin that is cytotoxic towards CD22-positive cells Biochem Soc Trans 25 1997 709 714
    • (1997) Biochem Soc Trans , vol.25 , pp. 709-714
    • Mansfield, E.1    Chiron, M.F.2    Amlot, P.3    Pastan, I.4    FitzGerald, D.J.5
  • 70
    • 0030954684 scopus 로고    scopus 로고
    • Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors
    • E. Mansfield, P. Amlot, I. Pastan, and D.J. FitzGerald Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors Blood 90 1997 2020 2026
    • (1997) Blood , vol.90 , pp. 2020-2026
    • Mansfield, E.1    Amlot, P.2    Pastan, I.3    FitzGerald, D.J.4
  • 71
    • 0028335616 scopus 로고
    • Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions
    • Y. Reiter, U. Brinkmann, R.J. Kreitman, S.-H. Jung, B. Lee, and I. Pastan Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions Biochemistry 33 1994 5451 5459
    • (1994) Biochemistry , vol.33 , pp. 5451-5459
    • Reiter, Y.1    Brinkmann, U.2    Kreitman, R.J.3    Jung, S.-H.4    Lee, B.5    Pastan, I.6
  • 72
    • 0034048735 scopus 로고    scopus 로고
    • Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) towards fresh malignant cells from patients with B-cell leukemias
    • R.J. Kreitman, I. Margulies, M. Stetler-Stevenson, Q.C. Wang, D.J.P. FitzGerald, and I. Pastan Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) towards fresh malignant cells from patients with B-cell leukemias Clin Cancer Res 6 2000 1476 1487
    • (2000) Clin Cancer Res , vol.6 , pp. 1476-1487
    • Kreitman, R.J.1    Margulies, I.2    Stetler-Stevenson, M.3    Wang, Q.C.4    FitzGerald, D.J.P.5    Pastan, I.6
  • 73
    • 0033047767 scopus 로고    scopus 로고
    • Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys
    • R.J. Kreitman, Q.C. Wang, D.J.P. FitzGerald, and I. Pastan Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys Int J Cancer 81 1999 148 155
    • (1999) Int J Cancer , vol.81 , pp. 148-155
    • Kreitman, R.J.1    Wang, Q.C.2    FitzGerald, D.J.P.3    Pastan, I.4
  • 74
    • 0030862195 scopus 로고    scopus 로고
    • Vascular leak syndrome: A side effect of immunotherapy
    • R. Baluna, and E.S. Vitetta Vascular leak syndrome: a side effect of immunotherapy Immunopharmacology 37 1997 117 132
    • (1997) Immunopharmacology , vol.37 , pp. 117-132
    • Baluna, R.1    Vitetta, E.S.2
  • 75
    • 0036554968 scopus 로고    scopus 로고
    • Improved cytotoxic activity towards cell lines and fresh leukemia cells of a mutant anti-CD22 immunotoxin obtained by antibody phage display
    • G. Salvatore, R. Beers, I. Margulies, R.J. Kreitman, and I. Pastan Improved cytotoxic activity towards cell lines and fresh leukemia cells of a mutant anti-CD22 immunotoxin obtained by antibody phage display Clin Cancer Res 8 2002 995 1002
    • (2002) Clin Cancer Res , vol.8 , pp. 995-1002
    • Salvatore, G.1    Beers, R.2    Margulies, I.3    Kreitman, R.J.4    Pastan, I.5
  • 76
    • 61349115036 scopus 로고    scopus 로고
    • CAT-8015: A second-generation pseudomonas exotoxin A-based immunotherapy targeting CD22-expressing hematologic malignancies
    • R.F. Alderson, R.J. Kreitman, T. Chen, P. Yeung, R. Herbst, J.A. Fox, and et al. CAT-8015: a second-generation pseudomonas exotoxin A-based immunotherapy targeting CD22-expressing hematologic malignancies Clin Cancer Res 15 2009 832 839
    • (2009) Clin Cancer Res , vol.15 , pp. 832-839
    • Alderson, R.F.1    Kreitman, R.J.2    Chen, T.3    Yeung, P.4    Herbst, R.5    Fox, J.A.6
  • 77
    • 84908031590 scopus 로고    scopus 로고
    • An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies
    • T.K. Bera, M. Onda, R.J. Kreitman, and I. Pastan An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies Leuk Res 38 2014 1224 1229
    • (2014) Leuk Res , vol.38 , pp. 1224-1229
    • Bera, T.K.1    Onda, M.2    Kreitman, R.J.3    Pastan, I.4
  • 78
    • 84902202498 scopus 로고    scopus 로고
    • Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
    • R. Mazor, J. Eberle, X. Hu, A.N. Vassall, M. Onda, R. Beers, and et al. Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes Proc Natl Acad Sci U. S. A. 111 2014 8571 8576
    • (2014) Proc Natl Acad Sci U. S. A. , vol.111 , pp. 8571-8576
    • Mazor, R.1    Eberle, J.2    Hu, X.3    Vassall, A.N.4    Onda, M.5    Beers, R.6
  • 79
    • 0030725160 scopus 로고    scopus 로고
    • An early step in Pseudomonas exotoxin action is removal of the terminal lysine residue, which allows binding to the KDEL receptor
    • J.L. Hessler, and R.J. Kreitman An early step in Pseudomonas exotoxin action is removal of the terminal lysine residue, which allows binding to the KDEL receptor Biochemistry 36 1997 14577 14582
    • (1997) Biochemistry , vol.36 , pp. 14577-14582
    • Hessler, J.L.1    Kreitman, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.