The prevalence of human papillomavirus infections and associated risk factors in men-who-have-sex-with-men in Cape Town, South Africa

BMC Infectious Diseases

Volumn 16, Issue 1, 2016, Pages

  Müller, Etienne E ^a   Rebe, Kevin ^b,c   Chirwa, Tobias F ^d   Struthers, Helen ^b,c   McIntyre, James ^b,c   Lewis, David A ^e,f  

^a NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^b ANOVA HEALTH INSTITUTE   (South Africa)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^e WESTERN SYDNEY SEXUAL HEALTH CENTRE   (Australia)

^f UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Anal; HPV; MSM; Oro pharyngeal; Risk factors; South Africa; Urine

Indexed keywords

ADULT; ANAL INTERCOURSE; ARTICLE; BLACK PERSON; CAUCASIAN; CONTROLLED STUDY; EDUCATIONAL STATUS; GROUP SEX; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN PAPILLOMAVIRUS TYPE 11; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HUMAN PAPILLOMAVIRUS TYPE 6; INFECTION RISK; MALE; MEN WHO HAVE SEX WITH MEN; MIXED INFECTION; NONHUMAN; PAPILLOMAVIRUS INFECTION; PREVALENCE; QUESTIONNAIRE; RACISM; RISK ASSESSMENT; RISK FACTOR; SOUTH AFRICA; THROAT CULTURE; URINALYSIS; VIRUS DETECTION; VIRUS GENOME; ANAL CANAL; CROSS-SECTIONAL STUDY; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; MALE HOMOSEXUALITY; MIDDLE AGED; OROPHARYNX; PAPILLOMAVIRIDAE; PATHOLOGY; SEXUALLY TRANSMITTED DISEASE; VIROLOGY; YOUNG ADULT;

ADULT; ANAL CANAL; COINFECTION; CROSS-SECTIONAL STUDIES; GENOTYPE; HIV INFECTIONS; HOMOSEXUALITY, MALE; HUMAN PAPILLOMAVIRUS 16; HUMAN PAPILLOMAVIRUS 6; HUMANS; MALE; MIDDLE AGED; OROPHARYNX; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; PREVALENCE; RISK FACTORS; SEXUALLY TRANSMITTED DISEASES; SOUTH AFRICA; YOUNG ADULT;

EID: 84983086219     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-016-1706-9     Document Type: Article

References (45)

1. Giuliano AR, Tortolero-Luna G, Ferrer E, Burchell AN, de Sanjose S, Kjaer SK, Munoz N, Schiffman M, Bosch FX. Epidemiology of human papillomavirus infection in men, cancers other than cervical and benign conditions. Vaccine. 2008;26 Suppl 10:K17-28.
2. Rositch AF, Mao L, Hudgens MG, Moses S, Agot K, Backes DM, Nyagaya E, Snijders PJ, Meijer CJ, Bailey RC, et al. Risk of HIV acquisition among circumcised and uncircumcised young men with penile human papillomavirus infection. AIDS. 2014;28(5):745-52.
3. Mbulawa ZZ, Marais DJ, Johnson LF, Coetzee D, Williamson AL. Impact of human immunodeficiency virus on the natural history of human papillomavirus genital infection in South African men and women. J Infect Dis. 2012;206(1):15-27.
4. Shisana O, Rehle T, Simbayi LC, Zuma K, Jooste S, Zungu N, Labadarios D, Onoya D. South African National HIV Prevalence, Incidence and Behaviour Survey. Cape Town: HSRC Press; 2012. ISBN 978-0-7969-2456-8 2014.
5. Human Sciences Research Council. Three cities study: high levels of HIV infection found among men who have sex with men: The South African Marang Men's Project. 2014. http://www.hsrc.ac.za/en/media-briefs/hiv-aids-stis-and-tb/marang. Accessed 13 Aug 2015.
6. Baggaley RF, White RG, Boily MC. HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV prevention. Int J Epidemiol. 2010;39(4):1048-63.
7. Machalek DA, Poynten M, Jin F, Fairley CK, Farnsworth A, Garland SM, Hillman RJ, Petoumenos K, Roberts J, Tabrizi SN, et al. Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis. Lancet Oncol. 2012;13(5):487-500.
8. Mendez-Martinez R, Rivera-Martinez NE, Crabtree-Ramirez B, Sierra-Madero JG, Caro-Vega Y, Galvan SC, de Leon DC, Garcia-Carranca A. Multiple human papillomavirus infections are highly prevalent in the anal canal of human immunodeficiency virus-positive men who have sex with men. BMC Infect Dis. 2014;14:671.
9. Supindham T, Chariyalertsak S, Utaipat U, Miura T, Ruanpeng D, Chotirosniramit N, Kosashunhanan N, Sugandhavesa P, Saokhieo P, Songsupa R, et al. High Prevalence and Genotype Diversity of Anal HPV Infection among MSM in Northern Thailand. PLoS One. 2015;10(5):e0124499.
10. Wirtz AL, Zelaya CE, Peryshkina A, McGowan I, Cranston RD, Latkin C, Galai N, Mogilniy V, Dzhigun P, Kostetskaya I, et al. Anal human papillomavirus and HIV: A cross-sectional study among men who have sex with men in Moscow, Russia, 2012-2013. Euro Surveill. 2015;20(15):pii=21095.
11. Hu Y, Qian HZ, Sun J, Gao L, Yin L, Li X, Xiao D, Li D, Sun X, Ruan Y, et al. Anal human papillomavirus infection among HIV-infected and uninfected men who have sex with men in Beijing, China. J Acquir Immune Defic Syndr. 2013;64(1):103-14.
12. de Pokomandy A, Rouleau D, Ghattas G, Vezina S, Cote P, Macleod J, Allaire G, Franco EL, Coutlee F. Prevalence, clearance, and incidence of anal human papillomavirus infection in HIV-infected men: the HIPVIRG cohort study. J Infect Dis. 2009;199(7):965-73.
13. Read TR, Hocking JS, Vodstrcil LA, Tabrizi SN, McCullough MJ, Grulich AE, Garland SM, Bradshaw CS, Chen MY, Fairley CK. Oral human papillomavirus in men having sex with men: risk-factors and sampling. PLoS One. 2012;7(11):e49324.
14. King EM, Gilson R, Beddows S, Soldan K, Panwar K, Young C, Jit M, Edmunds WJ, Sonnenberg P. Oral human papillomavirus (HPV) infection in men who have sex with men: prevalence and lack of anogenital concordance. Sex Transm Infect. 2015;91(4):284-6.
15. Shigehara K, Sasagawa T, Namiki M. Human papillomavirus infection and pathogenesis in urothelial cells: a mini-review. J Infect Chemother. 2014;20(12):741-7.
16. SANAC. National Strategic Plan on HIV, STIs and TB: 2012-2016. Edited by SANAC. Pretoria: SANAC; 2012.
17. Rebe K, Lewis D, Myer L, de Swardt G, Struthers H, Kamkuemah M, McIntyre J. A Cross Sectional Analysis of Gonococcal and Chlamydial Infections among Men-Who-Have-Sex-with-Men in Cape Town, South Africa. PLoS One. 2015;10(9):e0138315.
18. South African Department of Health. First Line Comprehensive Management and Control of Sexually Transmitted Infections (STIs). Protocol for the management of a person with a sexually transmitted infection according to the essential drug list. 2003. Department of Health. http://www.nicd.ac.za/assets/files/STI%20Book%202008%20Edited(1).pdf. Accessed 07 June 2016.
19. Nyitray AG, da Silva RJ C, Baggio ML, Lu B, Smith D, Abrahamsen M, Papenfuss M, Villa LL, Lazcano-Ponce E, Giuliano AR. Age-specific prevalence of and risk factors for anal human papillomavirus (HPV) among men who have sex with women and men who have sex with men: the HPV in men (HIM) study. J Infect Dis. 2011;203(1):49-57.
20. Goldstone S, Palefsky JM, Giuliano AR, Moreira Jr ED, Aranda C, Jessen H, Hillman RJ, Ferris DG, Coutlee F, Liaw KL, et al. Prevalence of and risk factors for human papillomavirus (HPV) infection among HIV-seronegative men who have sex with men. J Infect Dis. 2011;203(1):66-74.
21. Quinn R, Salvatierra J, Solari V, Calderon M, Ton TG, Zunt JR. Human papillomavirus infection in men who have sex with men in Lima, Peru. AIDS Res Hum Retroviruses. 2012;28(12):1734-8.
22. Latini A, Dona MG, Ronchetti L, Giglio A, Moretto D, Colafigli M, Laquintana V, Frasca M, Zaccarelli M, Antinori A, et al. Prevalence of anal human papillomavirus infection and cytologic abnormalities among HIV-infected and HIV-uninfected men who have sex with men. J Int AIDS Soc. 2014;17(4 Suppl 3):19662.
23. Zou H, Tabrizi SN, Grulich AE, Garland SM, Hocking JS, Bradshaw CS, Morrow A, Prestage G, Cornall AM, Fairley CK, et al. Early acquisition of anogenital human papillomavirus among teenage men who have sex with men. J Infect Dis. 2014;209(5):642-51.
24. Colon-Lopez V, Ortiz AP, Del Toro-Mejias L, Clatts MC, Palefsky JM. Epidemiology of anal HPV infection in high-risk men attending a sexually transmitted infection clinic in Puerto Rico. PLoS One. 2014;9(1):e83209.
25. Silverberg MJ, Lau B, Justice AC, Engels E, Gill MJ, Goedert JJ, Kirk GD, D'Souza G, Bosch RJ, Brooks JT, et al. Risk of anal cancer in HIV-infected and HIV-uninfected individuals in North America. Clin Infect Dis. 2012;54(7):1026-34.
26. Gao L, Zhou F, Li X, Yang Y, Ruan Y, Jin Q. Anal HPV infection in HIV-positive men who have sex with men from China. PLoS One. 2010;5(12):e15256.
27. Torres M, Gonzalez C, del Romero J, Viciana P, Ocampo A, Rodriguez-Fortunez P, Masia M, Blanco JR, Portilla J, Rodriguez C, et al. Anal human papillomavirus genotype distribution in HIV-infected men who have sex with men by geographical origin, age, and cytological status in a Spanish cohort. J Clin Microbiol. 2013;51(11):3512-20.
28. Sahasrabuddhe VV, Castle PE, Follansbee S, Borgonovo S, Tokugawa D, Schwartz LM, Lorey TS, LaMere BJ, Gage JC, Fetterman B, et al. Human papillomavirus genotype attribution and estimation of preventable fraction of anal intraepithelial neoplasia cases among HIV-infected men who have sex with men. J Infect Dis. 2013;207(3):392-401.
29. Coutlee F, de Pokomandy A, Franco EL. Epidemiology, natural history and risk factors for anal intraepithelial neoplasia. Sex Health. 2012;9(6):547-55.
30. Sendagorta E, Herranz P, Guadalajara H, Zamora FX. [Early detection of anal intraepithelial neoplasia in high-risk patients]. Actas Dermosifiliogr. 2011;102(10):757-65.
31. D'Souza G, Fakhry C, Sugar EA, Seaberg EC, Weber K, Minkoff HL, Anastos K, Palefsky JM, Gillison ML. Six-month natural history of oral versus cervical human papillomavirus infection. Int J Cancer. 2007;121(1):143-50.
32. Narisawa-Saito M, Kiyono T. Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins. Cancer Sci. 2007;98(10):1505-11.
33. Walline HM, Komarck C, McHugh JB, Byrd SA, Spector ME, Hauff SJ, Graham MP, Bellile E, Moyer JS, Prince ME, et al. High-risk human papillomavirus detection in oropharyngeal, nasopharyngeal, and oral cavity cancers: comparison of multiple methods. JAMA Otolaryngol Head Neck Surg. 2013;139(12):1320-7.
34. Anantharaman D, Gheit T, Waterboer T, Abedi-Ardekani B, Carreira C, McKay-Chopin S, Gaborieau V, Marron M, Lagiou P, Ahrens W, et al. Human papillomavirus infections and upper aero-digestive tract cancers: the ARCAGE study. J Natl Cancer Inst. 2013;105(8):536-45.
35. Ribeiro KB, Levi JE, Pawlita M, Koifman S, Matos E, Eluf-Neto J, Wunsch-Filho V, Curado MP, Shangina O, Zaridze D, et al. Low human papillomavirus prevalence in head and neck cancer: results from two large case-control studies in high-incidence regions. Int J Epidemiol. 2011;40(2):489-502.
36. Michaud DS, Langevin SM, Eliot M, Nelson HH, Pawlita M, McClean MD, Kelsey KT. High-risk HPV types and head and neck cancer. Int J Cancer. 2014;135(7):1653-61.
37. Nichols AC, Dhaliwal SS, Palma DA, Basmaji J, Chapeskie C, Dowthwaite S, Franklin JH, Fung K, Kwan K, Wehrli B, et al. Does HPV type affect outcome in oropharyngeal cancer? J Otolaryngol Head Neck Surg. 2013;42:9.
38. Davidson CL, Richter KL, Van der Linde M, Coetsee J, Boy SC. Prevalence of oral and oropharyngeal human papillomavirus in a sample of South African men: a pilot study. S Afr Med J. 2014;104(5):358-61.
39. Mooij SH, Boot HJ, Speksnijder AG, Meijer CJ, King AJ, Verhagen DW, de Vries HJ, Quint WG, Molijn A, de Koning MN, et al. Six-month incidence and persistence of oral HPV infection in HIV-negative and HIV-infected men who have sex with men. PLoS One. 2014;9(6):e98955.
40. Parisi SG, Cruciani M, Scaggiante R, Boldrin C, Andreis S, Dal Bello F, Pagni S, Barelli A, Sattin A, Mengoli C, et al. Anal and oral human papillomavirus (HPV) infection in HIV-infected subjects in northern Italy: a longitudinal cohort study among men who have sex with men. BMC Infect Dis. 2011;11:150.
41. Blas MM, Brown B, Menacho L, Alva IE, Silva-Santisteban A, Carcamo C. HPV Prevalence in Multiple Anatomical Sites among Men Who Have Sex with Men in Peru. PLoS One. 2015;10(10):e0139524.
42. Nyitray AG, da Silva RJ C, Baggio ML, Smith D, Abrahamsen M, Papenfuss M, Lin HY, Quiterio M, Salmeron J, Lazcano-Ponce E, et al. Six-month incidence, persistence, and factors associated with persistence of anal human papillomavirus in men: the HPV in men study. J Infect Dis. 2011;204(11):1711-22.
43. Lu B, Viscidi RP, Lee JH, Wu Y, Villa LL, Lazcano-Ponce E, da Silva RJ, Baggio ML, Quiterio M, Salmeron J, et al. Human papillomavirus (HPV) 6, 11, 16, and 18 seroprevalence is associated with sexual practice and age: results from the multinational HPV Infection in Men Study (HIM Study). Cancer Epidemiol Biomarkers Prev. 2011;20(5):990-1002.
44. Hernandez BY, Wilkens LR, Zhu X, Thompson P, McDuffie K, Shvetsov YB, Kamemoto LE, Killeen J, Ning L, Goodman MT. Transmission of human papillomavirus in heterosexual couples. Emerg Infect Dis. 2008;14(6):888-94.
45. Palefsky J, Giuliano A. Quadrivalent HPV vaccine efficacy in men having sex with men. Malmo: Paper presented at: International Papillomavirus Conference; May 2009; 2009.