Comparing the effect of bleach and water baths on skin barrier function in atopic dermatitis: a split-body randomized controlled trial

British Journal of Dermatology

Volumn 175, Issue 1, 2016, Pages 212-214

  Shi, V Y ^a   Foolad, N ^a   Ornelas, J N ^a   Hassoun, L A ^a   Monico, G ^a   Takeda, N ^a   Saric, S ^a   Prakash, N ^a   Eichenfield, L F ^b,c   Sivamani, R K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RADY CHILDREN'S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEACHING AGENT;

ADULT; ATOPIC DERMATITIS; BATH; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; ECZEMA AREA SEVERITY INDEX; FEMALE; HUMAN; LETTER; MALE; MIDDLE AGED; PH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SCHOOL CHILD; SKIN BARRIER FUNCTION; SKIN FUNCTION; YOUNG ADULT;

EID: 84982873315     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/bjd.14483     Document Type: Letter

References (13)

1. Guzik TJ, Bzowska M, Kasprowicz A et al. Persistent skin colonization with Staphylococcus aureus in atopic dermatitis: relationship to clinical and immunological parameters. Clin Exp Allergy 2005; 35:448–55.
2. Hon KL, Tsang YC, Lee VW et al. Efficacy of sodium hypochlorite (bleach) baths to reduce Staphylococcus aureus colonization in childhood onset moderate-to-severe eczema: a randomized, placebo-controlled cross-over trial. J Dermatolog Treat 2016; 27:156–62.
3. Huang JT, Abrams M, Tlougan B et al. Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity. Pediatrics 2009; 123:e808–14.
4. Metry D, Browning J, Rousseau A et al. Sodium hypochlorite (bleach) baths: a potential measure to reduce the incidence of recurrent, cutaneous Staphylococcus aureus superinfection among susceptible populations. Poster presentation at the Society for Pediatric Dermatology Annual Meeting, Chicago, IL, U.S.A., 12–15 July 2007.
5. Bath-Hextall FJ, Birnie AJ, Ravenscroft JC, Williams HC. Interventions to reduce Staphylococcus aureus in the management of atopic eczema: an updated Cochrane review. Br J Dermatol 2011; 164:228.
6. American Academy of Dermatology. Eczema: bleach bath therapy. Available at: www.aad.org (last accessed 31 May 2016).
7. American Academy of Allergy Asthma & Immunology. Bleach bath recipe for skin conditions. Available at: https://www.aaaai.org/conditions-and-treatments/library/allergy-library/bleach-bath-recipe-for-skin-conditions.aspx (last accessed 31 May 2016).
8. Hostynek JJ, Wilhelm KP, Cua AB, Maibach HI. Irritation factors of sodium hypochlorite solutions in human skin. Contact Dermatitis 1990; 23:316–24.
9. Sivamani RK, Wu GC, Gitis NV, Maibach HI. Tribological testing of skin products: gender, age, and ethnicity on the volar forearm. Skin Res Technol 2003; 9:299–305.
10. Chiang C, Eichenfield LF. Quantitative assessment of combination bathing and moisturizing regimens on skin hydration in atopic dermatitis. Pediatr Dermatol 2009; 26:273–8.
11. Hanifin JM, Thurston M, Omoto M et al. The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator Group. Exp Dermatol 2001; 10:11–18.
12. Craig FE, Smith EV, Williams HC. Bleach baths to reduce severity of atopic dermatitis colonized by Staphylococcus. Arch Dermatol 2010; 146:541–3.
13. Krakowski AC, Eichenfield LF, Dohil MA. Management of atopic dermatitis in the pediatric population. Pediatrics 2008; 122:812–24.