A topical antibacterial ointment made of Zn-doped copper oxide nanocomposite

Journal of Nanoparticle Research

Volumn 18, Issue 8, 2016, Pages

  Deokar, Archana R ^a   Shalom, Yakov ^a   Perelshtein, I ^a   Perkas, N ^a   Gedanken, A ^a,b   Banin, E ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Antibacterial ointment; Antibiofilm; Biofilm; Disrupting existing; Metal oxide; Nanocomposite

Indexed keywords

BACTERIA; BIOFILMS; COPPER; COPPER OXIDES; ENZYME INHIBITION; METALS; NANOCOMPOSITES;

ANTI-BIOFILM; ANTIBACTERIAL OINTMENT; DISRUPTING EXISTING; METAL OXIDES; PSEUDOMONAS AERUGINOSA; SPHERICAL NANOPARTICLES; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

ZINC;

ANTIINFECTIVE AGENT; COPPER OXIDE NANOCOMPOSITE; GENTAMICIN; NANOCOMPOSITE; UNCLASSIFIED DRUG; ZINC;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOFILM; CONTROLLED STUDY; DRUG FORMULATION; NONHUMAN; OINTMENT; PARTICLE SIZE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; WOUND;

EID: 84982842636     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-016-3534-7     Document Type: Article

References (23)

1. Agnihotri S, Bajaj G, Mukherji S, Mukherji S (2015) Arginine-assisted immobilization of silver nanoparticles on ZnO nanorods: an enhanced and reusable antibacterial substrate without human cell cytotoxicity. Nanoscale 7:7415–7429. doi:10.1039/C4NR06913G
2. Applerot G, Lipovsky A, Dror R et al (2009) Enhanced antibacterial activity of nanocrystalline ZnO due to increased ROS-mediated cell injury. Adv Funct Mater 19:842–852. doi:10.1002/adfm.200801081
3. Applerot G, Lellouche J, Perkas N et al (2012) ZnO nanoparticle-coated surfaces inhibit bacterial biofilm formation and increase antibiotic susceptibility. RSC Adv 2:2314–2321. doi:10.1039/c2ra00602b
4. Banerjee M, Sharma S, Chattopadhyay A, Ghosh SS (2011) Enhanced antibacterial activity of bimetallic gold-silver core–shell nanoparticles at low silver concentration. Nanoscale 3:5120–5125. doi:10.1039/c1nr10703h
5. Costerton JW, Stewart PS, Greenberg EP (1999) Bacterial biofilms: a common cause of persistent infections. Science 284:1318–1322. doi:10.1126/science.284.5418.1318
6. Demling RH, Waterhouse B (2007) The increasing problem of wound bacterial burden and infection in acute and chronic soft-tissue wounds caused by methicillin-resistant Staphylococcus aureus. J Burns Wounds 7:e8
7. Eshed M, Lellouche J, Gedanken A, Banin E (2014) A Zn-doped CuO nanocomposite shows enhanced antibiofilm and antibacterial activities against Streptococcus mutans compared to nanosized CuO. Adv Funct Mater 24:1382–1390. doi:10.1002/adfm.201302425
8. Gao W, Fang R, Thamphiwatana S et al (2015) Modulating antibacterial immunity via bacterial membrane-coated nanoparticles. Nano Lett 15:1403–1409. doi:10.1021/nl504798g
9. Gedanken A (2004) Using sonochemistry for the fabrication of nanomaterials. Ultrason Sonochem 11:47–55. doi:10.1016/j.ultsonch.2004.01.037
10. Gurunathan S, Han JW, Kwon D-N, Kim J-H (2014) Enhanced antibacterial and anti-biofilm activities of silver nanoparticles against Gram-negative and Gram-positive bacteria. Nanoscale Res Lett 9:373. doi:10.1186/1556-276X-9-373
11. Hammond AA, Miller KG, Kruczek CJ et al (2011) An in vitro biofilm model to examine the effect of antibiotic ointments on biofilms produced by burn wound bacterial isolates. Burns 37:312–321. doi:10.1016/j.burns.2010.09.017
12. Hansen SF, Baun A (2012) When enough is enough. Nat Nanotechnol 7:409–411. doi:10.1038/nnano.2012.115
13. Hill KE, Malic S, McKee R et al (2010) An in vitro model of chronic wound biofilms to test wound dressings and assess antimicrobial susceptibilities. J Antimicrob Chemother 65:1195–1206. doi:10.1093/jac/dkq105
14. 2 coated textiles to combat hospital acquired infections. RSC Adv 4:19945–19952. doi:10.1039/c4ra02759k
15. Lipsky BA, Hoey C (2009) Topical antimicrobial therapy for treating chronic wounds. Clin Infect Dis 49:1541–1549. doi:10.1086/644732
16. Mahmoudi M, Serpooshan V (2012) Silver-coated engineered magnetic nanoparticles are promising for the success in the fight against antibacterial resistance threat. ACS Nano 6:2656–2664. doi:10.1021/nn300042m
17. Malka E, Perelshtein I, Lipovsky A et al (2013) Eradication of multi-drug resistant bacteria by a novel Zn-doped CuO nanocomposite. Small 9:4069–4076. doi:10.1002/smll.201301081
18. Perelshtein I, Applerot G, Perkas N et al (2010) Ultrasound radiation as a “throwing stones” technique for the production of antibacterial nanocomposite textiles. ACS Appl Mater Interfaces 2:1999–2004. doi:10.1021/am100291w
19. Sen CK, Gordillo GM, Roy S et al (2009) Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen 17:763–771. doi:10.1111/j.1524-475X.2009.00543.x
20. Sevgi M, Toklu A, Vecchio D, Hamblin MR (2013) Topical antimicrobials for burn infections—an update. Recent Pat Antiinfect Drug Discov 8:161–197. doi:10.2174/1574891X08666131112143447
21. Suresh AK, Pelletier DA, Doktycz MJ (2013) Relating nanomaterial properties and microbial toxicity. Nanoscale 5:463–474. doi:10.1039/c2nr32447d
22. Wu H, Moser C, Wang HZ et al (2015) Strategies for combating bacterial biofilm infections. Int J Oral Sci 7:1–7. doi:10.1038/ijos.2014.65
23. Zhao G, Usui ML, Lippman SI et al (2013) Biofilms and inflammation in chronic wounds. Adv Wound Care 2:389–399. doi:10.1089/wound.2012.0381