Use of computer decision support in an antimicrobial stewardship program (ASP)

Applied Clinical Informatics

Volumn 6, Issue 1, 2015, Pages 120-135

  Evans, R Scott ^a,b   Olson, J A ^c   Stenehjem, E ^d   Buckel, W R ^d   Thorell, E A ^b   Howe, S ^a   Wu, X ^a   Jones, P S ^d   Lloyd, J F ^a  

^a INTERMOUNTAIN HEALTHCARE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

^d INTERMOUNTAIN MEDICAL CENTER   (United States)

Author keywords

Antibiotic resistance; Antimicrobial stewardship; Antimicrobial stewardship program; ASP; Clinical decision support; Computer decision support; Medical informatics; Patient specific alerts

Indexed keywords

ANTIINFECTIVE AGENT;

CHILD; CLINICAL AUDIT; CLINICAL DECISION SUPPORT SYSTEM; CRITICAL ILLNESS; E-MAIL; HOSPITAL; HUMAN; STATISTICS; STATISTICS AND NUMERICAL DATA; UTILIZATION;

ANTI-BACTERIAL AGENTS; CHILD; CLINICAL AUDIT; CRITICAL ILLNESS; DECISION SUPPORT SYSTEMS, CLINICAL; ELECTRONIC MAIL; HOSPITALS; HUMANS; STATISTICS AS TOPIC;

EID: 84982747201     PISSN: None     EISSN: 18690327     Source Type: Journal    
DOI: 10.4338/ACI-2014-11-RA-0102     Document Type: Article

References (51)

1. Gould IM, Bal AM. New antibiotic agents in the pipeline and how they can help overcome microbial resistance. Virulence 2013; 4(2): 185-191.
2. Livermore DM, British Society for Antimicrobial Chemotherapy Working Party on The Urgent Need: Regenerating Antibacterial Drug D, Development. Discovery research: the scientific challenge of finding new antibiotics. The Journal of antimicrobial chemotherapy 2011; 66(9): 1941-1944.
3. Malani AN, Richards PG, Kapila S, Otto MH, Czerwinski J, Singal B. Clinical and economic outcomes from a community hospital’s antimicrobial stewardship program. American journal of infection control 2013; 41(2): 145-148.
4. Dellit TH, Owens RC, McGowan JE, Jr., Gerding DN, Weinstein RA, Burke JP, Huskins WC, Paterson DL, Fishman NO, Carpenter CF, Brennan PJ, Billeter M, Hooton TM, Infectious Diseases Society of A, Society for Healthcare Epidemiology of A. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America 2007; 44(2): 159-177.
5. Yam P, Fales D, Jemison J, Gillum M, Bernstein M. Implementation of an antimicrobial stewardship program in a rural hospital. American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists 2012; 69(13): 1142-1148.
6. Magedanz L, Silliprandi EM, dos Santos RP. Impact of the pharmacist on a multidisciplinary team in an antimicrobial stewardship program: a quasi-experimental study. International journal of clinical pharmacy 2012; 34(2): 290-294.
7. Reed EE, Stevenson KB, West JE, Bauer KA, Goff DA. Impact of formulary restriction with prior authorization by an antimicrobial stewardship program. Virulence 2013; 4(2): 158-162.
8. Chalfine A, Kitzis MD, Bezie Y, Benali A, Perniceni L, Nguyen JC, Dumay MF, Gonot J, Rejasse G, Goldstein F, Carlet J, Misset B. Ten-year decrease of acquired methicillin-resistant Staphylococcus aureus (MRSA) bacteremia at a single institution: the result of a multifaceted program combining cross-transmission prevention and antimicrobial stewardship. Antimicrobial resistance and infection control 2012; 1(1): 18.
9. Cheng VC, To KK, Li IW, Tang BS, Chan JF, Kwan S, Mak R, Tai J, Ching P, Ho PL, Seto WH. Antimicrobial stewardship program directed at broad-spectrum intravenous antibiotics prescription in a tertiary hospital. European journal of clinical microbiology & infectious diseases: official publication of the European Society of Clinical Microbiology 2009; 28(12): 1447-1456.
10. Palmer HR, Weston J, Gentry L, Salazar M, Putney K, Frost C, Tipton JA, Cottreau J, Tam VH, Garey KW. Improving patient care through implementation of an antimicrobial stewardship program. American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists 2011; 68(22): 2170-2174.
11. Di Pentima MC, Chan S, Hossain J. Benefits of a pediatric antimicrobial stewardship program at a children’s hospital. Pediatrics 2011; 128(6): 1062-1070.
12. Wong-Beringer A, Nguyen LH, Lee M, Shriner KA, Pallares J. An antimicrobial stewardship program with a focus on reducing fluoroquinolone overuse. Pharmacotherapy 2009; 29(6): 736-743.
13. Katsios CM, Burry L, Nelson S, Jivraj T, Lapinsky SE, Wax RS, Christian M, Mehta S, Bell CM, Morris AM. An antimicrobial stewardship program improves antimicrobial treatment by culture site and the quality of antimicrobial prescribing in critically ill patients. Critical care 2012; 16(6): R216.
14. Beardsley JR, Williamson JC, Johnson JW, Luther VP, Wrenn RH, Ohl CC. Show me the money: long-term financial impact of an antimicrobial stewardship program. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2012; 33(4): 398-400.
15. Standiford HC, Chan S, Tripoli M, Weekes E, Forrest GN. Antimicrobial stewardship at a large tertiary care academic medical center: cost analysis before, during, and after a 7-year program. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2012; 33(4): 338-345.
16. Baker SN, Acquisto NM, Ashley ED, Fairbanks RJ, Beamish SE, Haas CE. Pharmacist-managed antimicrobial stewardship program for patients discharged from the emergency department. Journal of pharmacy practice 2012; 25(2): 190-194.
17. Slain D, Sarwari AR, Petros KO, McKnight RL, Sager RB, Mullett CJ, Wilson A, Thomas JG, Moffett K, Palmer HC, Dedhia HV. Impact of a Multimodal Antimicrobial Stewardship Program on Pseudomonas aeruginosa Susceptibility and Antimicrobial Use in the Intensive Care Unit Setting. Critical care research and practice 2011; 2011: 416426.
18. Burke JP. Antibiotic resistance--squeezing the balloon? JAMA: the journal of the American Medical Association 1998; 280(14): 1270-1271.
19. Classen DC, Evans RS, Pestotnik SL, Horn SD, Menlove RL, Burke JP. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. The New England journal of medicine 1992; 326(5): 281-286.
20. Evans RS, Classen DC, Pestotnik SL, Lundsgaarde HP, Burke JP. Improving empiric antibiotic selection using computer decision support. Archives of internal medicine 1994; 154(8): 878-884.
21. Evans RS, Larsen RA, Burke JP, Gardner RM, Meier FA, Jacobson JA, Conti MT, Jacobson JT, Hulse RK. Computer surveillance of hospital-acquired infections and antibiotic use. JAMA: the journal of the American Medical Association 1986; 256(8): 1007-1011.
22. Evans RS, Pestotnik SL, Burke JP, Gardner RM, Larsen RA, Classen DC. Reducing the duration of prophylactic antibiotic use through computer monitoring of surgical patients. DICP: the annals of pharmacotherapy 1990; 24(4): 351-354.
23. Evans RS, Pestotnik SL, Classen DC, Burke JP. Evaluation of a computer-assisted antibiotic-dose monitor. The Annals of pharmacotherapy 1999; 33(10): 1026-1031.
24. Evans RS, Pestotnik SL, Classen DC, Clemmer TP, Weaver LK, Orme JF, Jr., Lloyd JF, Burke JP. A computer-assisted management program for antibiotics and other antiinfective agents. The New England journal of medicine 1998; 338(4): 232-238.
25. Mullett CJ, Evans RS, Christenson JC, Dean JM. Development and impact of a computerized pediatric antiinfective decision support program. Pediatrics 2001; 108(4): E75.
26. Pestotnik SL, Classen DC, Evans RS, Burke JP. Implementing antibiotic practice guidelines through computer-assisted decision support: clinical and financial outcomes. Annals of internal medicine 1996; 124(10): 884-890.
27. Pestotnik SL, Evans RS, Burke JP, Gardner RM, Classen DC. Therapeutic antibiotic monitoring: surveillance using a computerized expert system. The American journal of medicine 1990; 88(1): 43-48.
28. Evans RS, Lloyd JF, Pierce LA. Clinical use of an enterprise data warehouse. AMIA Annual Symposium proceedings / AMIA Symposium AMIA Symposium 2012; 2012: 189-198.
29. Schwartz DN, Evans RS, Camins BC, Khan YM, Lloyd JF, Shehab N, Stevenson K. Deriving measures of intensive care unit antimicrobial use from computerized pharmacy data: methods, validation, and overcoming barriers. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2011; 32(5): 472-480.
30. Drew RH, Kawamoto K, Adams MB. Information technology for optimizing the management of infectious diseases. American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists 2006; 63(10): 957-965.
31. Pope SD, Dellit TH, Owens RC, Hooton TM, Infectious Diseases Society of A, Society for Healthcare Epidemiology of A. Results of survey on implementation of Infectious Diseases Society of America and Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2009; 30(1): 97-98.
32. Johannsson B, Beekmann SE, Srinivasan A, Hersh AL, Laxminarayan R, Polgreen PM. Improving antimicrobial stewardship: the evolution of programmatic strategies and barriers. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2011; 32(4): 367-374.
33. Trivedi KK, Rosenberg J. The state of antimicrobial stewardship programs in California. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2013; 34(4): 379-384.
34. Webber EC, Warhurst HM, Smith SS, Cox EG, Crumby AS, Nichols KR. Conversion of a single-facility pediatric antimicrobial stewardship program to multi-facility application with computerized provider order entry and clinical decision support. Applied clinical informatics 2013; 4(4): 556-568.
35. Po JL, Nguyen BQ, Carling PC. The impact of an infectious diseases specialist-directed computerized physician order entry antimicrobial stewardship program targeting linezolid use. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2012; 33(4): 434-435.
36. Linkin DR, Paris S, Fishman NO, Metlay JP, Lautenbach E. Inaccurate communications in telephone calls to an antimicrobial stewardship program. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2006; 27(7): 688-694.
37. Agwu AL, Lee CK, Jain SK, Murray KL, Topolski J, Miller RE, Townsend T, Lehmann CU. A World Wide Web-based antimicrobial stewardship program improves efficiency, communication, and user satisfaction and reduces cost in a tertiary care pediatric medical center. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America 2008; 47(6): 747-753.
38. Sick AC, Lehmann CU, Tamma PD, Lee CK, Agwu AL. Sustained savings from a longitudinal cost analysis of an internet-based preapproval antimicrobial stewardship program. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2013; 34(6): 573-580.
39. Johnson AP. Improving antimicrobial stewardship: AmWeb, a tool for helping microbiologists in England to ’Start Smart’ when advising on antibiotic treatment. The Journal of antimicrobial chemotherapy 2013; 68(10): 2181-2182.
40. Ironmonger D, Edeghere O, Gossain S, Bains A, Hawkey PM. AmWeb: a novel interactive web tool for antimicrobial resistance surveillance, applicable to both community and hospital patients. The Journal of antimicrobial chemotherapy 2013; 68(10): 2406-2413.
41. Elligsen M, Walker SA, Simor A, Daneman N. Prospective audit and feedback of antimicrobial stewardship in critical care: program implementation, experience, and challenges. The Canadian journal of hospital pharmacy 2012; 65(1): 31-36.
42. Nowak MA, Nelson RE, Breidenbach JL, Thompson PA, Carson PJ. Clinical and economic outcomes of a prospective antimicrobial stewardship program. American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists 2012; 69(17): 1500-1508.
43. Paul M, Andreassen S, Tacconelli E, Nielsen AD, Almanasreh N, Frank U, Cauda R, Leibovici L, Group TS. Improving empirical antibiotic treatment using TREAT, a computerized decision support system: cluster randomized trial. The Journal of antimicrobial chemotherapy 2006; 58(6): 1238-1245.
44. Lopez-Medrano F, Moreno-Ramos F, de Cueto M, Mora-Rillo M, Salavert M. How to assist clinicians in improving antimicrobial prescribing: tools and interventions provided by stewardship programs. Enfermedades infecciosas y microbiologia clinica 2013; 31 (Suppl. 4): 38-44.
45. Kaki R, Elligsen M, Walker S, Simor A, Palmay L, Daneman N. Impact of antimicrobial stewardship in critical care: a systematic review. The Journal of antimicrobial chemotherapy 2011; 66(6): 1223-1230.
46. Gerber JS, Prasad PA, Fiks AG, Localio AR, Grundmeier RW, Bell LM, Wasserman RC, Keren R, Zaoutis TE. Effect of an outpatient antimicrobial stewardship intervention on broad-spectrum antibiotic prescribing by primary care pediatricians: a randomized trial. JAMA: the journal of the American Medical Association 2013; 309(22): 2345-2352.
47. Ostrowsky B, Sharma S, DeFino M, Guo Y, Shah P, McAllen S, Chung P, Brown S, Paternoster J, Schechter A, Yongue B, Bhalla R. Antimicrobial stewardship and automated pharmacy technology improve antibiotic appropriateness for community-acquired pneumonia. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2013; 34(6): 566-572.
48. Perez KK, Olsen RJ, Musick WL, Cernoch PL, Davis JR, Land GA, Peterson LE, Musser JM. Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs. Archives of pathology & laboratory medicine 2013; 137(9): 1247-1254.
49. Pogue JM, Mynatt RP, Marchaim D, Zhao JJ, Barr VO, Moshos J, Sunkara B, Chopra T, Chidurala S, Kaye KS. Automated alerts coupled with antimicrobial stewardship intervention lead to decreases in length of stay in patients with gram-negative bacteremia. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2014; 35(2): 132-138.
50. Kullar R, Goff DA, Schulz LT, Fox BC, Rose WE. The „epic“ challenge of optimizing antimicrobial stewardship: the role of electronic medical records and technology. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America 2013; 57(7): 1005-1013.
51. Schulz L, Osterby K, Fox B. The use of best practice alerts with the development of an antimicrobial stewardship navigator to promote antibiotic de-escalation in the electronic medical record. Infection control and hospital epidemiology: the official journal of the Society of Hospital Epidemiologists of America 2013; 34(12): 1259-1265.