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7
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0004270887
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The chemistry of isocyanides has hitherto been limited largely to α‐addition of the isocyano group: review:, Academic Press, New york
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(1971)
Isonitrile Chemistry
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Ugi, I.1
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16
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0346231706
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-
(1957)
Pharmazie
, vol.12
, pp. 567
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39
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84982380167
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The bonding in organolithium compounds is complicated and varies according to the alkyl group and the solvent. For simplicity the lithiated isocyanides are here represented ionically in their structural formulas: cf., in [3 b], p.
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Schöllkopf, U.1
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42
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84982374421
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Dissertation, Universität Göttingen, planned for 1975.
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Harms, R.1
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54
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84982348047
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Dissertation, Universität Göttingen 1974.
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Thoms, R.1
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75
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84982355275
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Dissertation, Universität Göttingen 1973
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Hantke, K.1
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79
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25544480497
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1-Formylamino-1-arylsulfonyl-alkene aus α-metallierten Isocyanmethyl-arylsulfonen und Carbonylverbindungen; Umwandlung einer Carbonylverbindung in die nächsthöhere Carbonsäure
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(1972)
Angewandte Chemie
, vol.84
, pp. 289
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Schöllkopf, U.1
Schröder, R.2
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88
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84982367648
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For conversion of isocyanides into formamides and for deformylation see [39] and literature cited therein.
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94
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84982376751
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Dissertation, Universität Göttingen 1973.
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Jentsch, S.1
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98
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84912380900
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The original isomers ratio can be shifted to ca. 3:1 in favor of cis‐(59a) by double lithiation and protonation:, Universität Göttingen
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(1974)
Diplomarbeit
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Scheunemann, K.‐H.1
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110
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0001281349
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Neuere präparative Methoden der organischen Chemie II 13. Carbonyl-Olefinierung mit Triphenyl-phosphin-methylenen Wittig-Reaktion
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also [3 b] and previous reviews cited therein
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(1959)
Angewandte Chemie
, vol.71
, pp. 260
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Schöllkopf, U.1
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111
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84982384810
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2-Alkylthio-2-oxazolin-4-carbonsäureester und ihre Umwandlung in α-(N-Alkylthiocarbonyl-amino)acrylsäureester
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For analogous ring openings see [36]; also
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(1973)
Angewandte Chemie
, vol.85
, pp. 660
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Hoppe, D.1
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113
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84982355299
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Dissertation, Universität Göttingen 1969.
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Markusch, P.1
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115
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84982359845
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71c was obtained only in the indicated configuration;, Berlin, personal communication.
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Haffer, G.1
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132
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84982363507
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For recognition of the relative configuration only one enantiomer is shown.
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-
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148
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84982374953
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Dissertation, Universität Göttingen 1972.
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Schröder, R.1
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151
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84982380973
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Dissertation, Universität Göttingen. 1974
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Eilers, E.1
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154
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84982368552
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Dehydration of diethyl formylaminomalonate also affords the 5‐alkoxy‐oxazole
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Gerhart, F.1
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155
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84982358169
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It is surprising that the esters 125 do not at least partially cyclize under the alkaline reaction conditions since ethyl α‐isocyanophenylacetate gives mainly 5‐ethoxy‐4‐phenyloxazole on distillation
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Hoppe, D.1
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156
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84982381722
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Dissertation, Universität Göttingen 1974.
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Böhme, P.1
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161
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84982366339
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Dissertation, Universität Göttingen 1973.
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Porsch, P‐H.1
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173
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84982077638
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Synthesen mit α-metallierten Isocyaniden, XXV. 4-Cyan-2-isocyanalkansäure-äthylester, 4-Cyan-2-(formylamino)alkansäure-äthylester und 4-Cyan-5(4)-pyrrolin-2-carbonsäure-äthylester aus α-metallierten Isocyanalkansäure-äthylestern und Acrylnitrilen
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(1973)
Chemische Berichte
, vol.106
, pp. 3382
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Schöllkopf, U.1
Porsch, P‐H.2
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183
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33847805571
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As recently reported, (+)‐(S)‐l‐isocyano‐2,2‐diphenylcyclopropyllithium is configurationally stable below −50°C. It follows that mesomeric stabilization by the isocyano group plays no part: see:,. Notes added in proof (November 21, 1974)
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(1974)
J. Amer Chem. Soc.
, vol.96
, pp. 3711
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Walborsky, H.M.1
Periasamy, M.P.2
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184
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84982353104
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very recently the first vinyl isocyanide 63 has been metalated: E/Z‐β‐styryl isocyanide 63a was lithiated with n‐butyllithium in tetrahydrofuran/ n‐pentane/diethyl ether (4:1:1) at −110°C (trapped by methyl iodide, trimethylchlorosilane, carbonyl compounds, and carbon dioxide)
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186
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84982351194
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2R in 71) on warming to 0°C in the presence of excess base. The reaction sequence with subsequent acid hydrolysis affords an “Eintopf” synthesis of 3‐ or 4‐pyridylalkyl (or aryl)ketones of type 76 in yields of 60 to 80
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