Effect of anaemia on hand grip strength, walking speed, functionality and 1 year mortality in older hospitalized patients

BMC Geriatrics

Volumn 16, Issue 1, 2016, Pages

  Joosten, Etienne ^a   Detroyer, Elke ^a,b   Milisen, Koen ^a,b  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Activities of daily living; Anaemia; Gait speed; Hand grip strength; Hospitalized older patients

Indexed keywords

C REACTIVE PROTEIN; HEMOGLOBIN;

AGED; ANEMIA; BELGIUM; DAILY LIFE ACTIVITY; EPIDEMIOLOGY; FEMALE; GERIATRIC ASSESSMENT; HAND STRENGTH; HOSPITALIZATION; HUMAN; MALE; MORTALITY; ODDS RATIO; PATHOPHYSIOLOGY; PROCEDURES; PROSPECTIVE STUDY; RISK FACTOR; SEVERITY OF ILLNESS INDEX; STATISTICS AND NUMERICAL DATA; VERY ELDERLY; WALKING SPEED;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; ANEMIA; BELGIUM; C-REACTIVE PROTEIN; FEMALE; GERIATRIC ASSESSMENT; HAND STRENGTH; HEMOGLOBINS; HOSPITALIZATION; HUMANS; MALE; MORTALITY; ODDS RATIO; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; WALKING SPEED;

EID: 84982272623     PISSN: None     EISSN: 14712318     Source Type: Journal    
DOI: 10.1186/s12877-016-0326-y     Document Type: Article

References (34)

1. Beghé C, Wilson A, Ershler WB. Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature. Am J Med. 2004;116:3S-10S.
2. Gaskell H, Derry S, Moore RA, McQuay HJ. Prevalence of anaemia in older persons: systematic review. BMC Geriatrics. 2008. doi: 10.11186/1471-2318-8-1.
3. Patel KV. Epidemiology of anaemia in older adults. Semin Hematol. 2008;45:210-7.
4. Maraldi C, Volpato S, Cesari M, Cavalieri M, Graziano O, Mangani I, Woodman RC, Fellin R, Pahor M. Anemia and recovery from disability in activities of daily living in hospitalized older persons. J Am Geriatr Soc. 2006;54:632-6.
5. Guralnik JM, Eisenstaedt FL, Klein HG, Woodman RC. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004;1041:2263-8.
6. Robinson B, Artz AS, Culleton B, Critchlow C, Sciarra A, Audhya P. Prevalence of anemia in the nursing home: contribution of chronic kidney disease. J Am Geriatr Soc. 2007;55:1566-70.
7. Penninx BWJH, Pahor M, Cesari M, Corsi AM, Woodman RC, Bandinelli S, Guralnik JM, Ferrucci L. Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc. 2004;52:719-24.
8. Penninx BWJH, Pahor M, Woodman RC, Guralnik JM. Anemia in old age is associated with increased mortality and hospitalization. J Gerontol A Biol Sci Med Sci. 2006;61:474-9.
9. Culleton BF, Manns BJ, Zhang J, Tonelli M, Klarenbach S, Hemmelgarn BR. Impact of anemia on hospitalization and mortality in older adults. Blood. 2006;107:3841-6.
10. Aung KCY, Feng L, Yap KB, Sitoh YY, Leong IYO, Ng TP. Serum albumin and haemoglobin are associated with physical function in community-living older persons in Singapore. J Nutr Health Aging. 2011;15:877-82.
11. Haslam A, Davey A, Cress ME. Association between anemia and physical function in Georgia centenarians. J Am Geriatr Soc. 2012;60:2362-3.
12. Joosten E, Demuynck M, Detroyer E, Milisen K. Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients. BMC Geriatr. 2014;14:1. doi: 10.1186/1471-2318-14-1.
13. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146-56.
14. Alley DE, Shardell MD, Peters KW, McLean RR, Dam T-TL, Kenny AM, Fragala MS, Harris TB, Kiel DP, Guralnik JM, Ferrucci L, Kritchevsky SB, Studneski SA, Vassileva MT, Cawthon PM. Grip strength cutpoints for the identification of clinically relevant weakness. J Gerontol A Biol Sci Med Sci. 2014;69:559-66.
15. Katz S, Akpom CA. Index of ADL. Med Care. 1976;14:116-8.
16. Braekhus A, Laake K, Engedal K. The Mini Mental State Examination: identifying the most efficient variables for detecting cognitive impairment in the elderly. J Am Geriatr Soc. 1992;40:1139-45.
17. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-83.
18. Joosten E, Lemiengre J, Nelis T, Verbeke G, Milisen K. Is anaemia a risk factor for delirium in an acute geriatric population? Gerontology. 2006;52:382-5.
19. Chaves PH, Xue QL, Guralnik JM, Ferrucci L, Volpato S, Fried LP. What constitutes normal hemoglobin concentration in community-dwelling disabled older women? J Am Geriatr Soc. 2004;52:1811-6.
20. Denny SD, Kuchibhatla MN, Cohen HJ. Impact of anemia on mortality, cognition, and function in community-dwelling elderly. Am J Med. 2006;119:327-34.
21. Hong CH, Falvey C, Harris TB, Simonsick EM, Satterfield S, Ferrucci L, Metti AL, Patel KV, Yaffe K. Anemia and risk of dementia in older adults: findings from the health ABC study. Neurology. 2013;81:528-33.
22. Riva E, Tettamanti M, Mosconi P, Apolone G, Gandini F, Nobili A, Tallone MV, Detoma P, Giacomin A, Clerico M, Tempia P, Guala A, Fasolo G, Lucca U. Association of mild anemia with hospitalization and mortality in the elderly: the Health and anemia population-based study. Haematologica. 2009;94:22-8.
23. Den Elzen WPJ, Willems JM, Westendorp RGJ, de Craen AJM, Assendelft WJJ, Gussekloo J. Effect of anemia and comorbidity on functional status and mortality in old age: results from the Leiden 85-plus study. CMAJ. 2009. doi: 10.1503/cmaj.090040.
24. Chaves PHM, Ashar B, Guralnik JM, Fried LP. Looking at the relationship between hemoglobin concentration and prevalent mobility difficulty in older women. Should the criteria currently used to define anemia in older people be reevaluated ? J Am Geriatr Soc. 2002;50:1257-64.
25. Bang S-M, Lee J-O, Kim YJ, Lee K-W, Lim S, Kim JH, Park YJ, Chin HJ, Kim KW, Jang H-C, Lee JS. Anemia and activities of daily living in the Korean urban elderly population: results from the Korean Longitudinal study on health and aging (KLoSHA). Ann Hematol. 2013;92:59-65.
26. Corona LP, Andrade FC, Duarte YA, Lebrao ML. The association of hemoglobin concentration with disability and decreased mobility among older Brazilians. J Nutr Health Aging. 2014;18:336-41.
27. Thein M, Ershler WB, Artz AS, Tecson J, Robinson BE, Rothstein G, Liede A, Gylys-Colwell I, Lu ZJ, Robbins S. Diminished quality of life and physical function in community-dwelling elderly with anemia. Medicine. 2009;88:107-14.
28. Zilinski J, Zillmann R, Becker I, Benzing T, Schulz R-J, Roehrig G. Prevalence of anemia among elderly inpatients and its association with multidimensional loss of function. Ann Hematol. 2014;93:1645-54.
29. Liu Z, Wang Y, Wang Y, Huang J, Chu X, Qian D, Wang Z, Sun X, Chen F, Xu J, Jin L, Wang X. Blood biomarkers and functional disability among extremely longevous individuals: a population-based study. J Gerontol A Biol Sci Med Sci. 2015;623-627 doi: 10.1093/gerona/glu229.
30. Ishine M, Wada T, Akamatsu K, Cruz MR. No positive correlation between anemia and disability in older people in Japan. J Am Geriatr Soc. 2004;52:719-24.
31. Cesari M, Penninx BWJH, Lauretani F, Russo CR, Carter C, Bandinelli S, Atkinson H, Onder G, Pahor M, Ferrucci L. Hemoglobin levels and skeletal muscle: results from the InCHIANTI Study. J Gerontol A Biol Sci Med Sci. 2004;59:249-54.
32. Tiainen K, Hurme M, Hervonen A, Luukkaala T, Jylhä M. Inflammatory markers and physical performance among nonagenarians. J Gerontol A Biol Sci Med Sci. 2010;65(6):658-63. doi: 10.1093/Gerona/glq056.
33. Ostir GV, Berges I, Kuo Y-F, Goodwin JS, Ottenbacher KJ, Guralnik JM. Assessing gait speed in acutely ill older patients admitted to an acute care for elders Hospital Unit. Arch Intern Med. 2012;172:353-8.
34. Roberts HC, Syddall HE, Cooper C, Sayer AA. Is grip strength associated with length of stay in hospitalized older patients admitted for rehabilitation? Findings form the Southampton grip strength study. Age Ageing. 2012;41:641-6.