A synchronized prescription refill program improved medication adherence

Health Affairs

Volumn 35, Issue 8, 2016, Pages 1504-1512

  Doshi, Jalpa A ^a,b   Lim, Raymond ^a   Li, Pengxiang ^a   Young, Peinie P ^c,d   Lawnicki, Victor F ^e   State, Joseph J ^e   Troxel, Andrea B ^a,b   Volpp, Kevin G ^a,b,f,g  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HUMANA INC   (United States)

^d CARDINAL HEALTH   (United States)

^e Humana   (United States)

^f Corporal Michael J Crescenz VA Medical Center ^*  (United States)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT;

AGED; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; INSURANCE; MAJOR CLINICAL STUDY; MALE; MEDICARE; MEDICATION COMPLIANCE; OUTCOME ASSESSMENT; PRESCRIPTION; QUASI EXPERIMENTAL STUDY; SENSITIVITY ANALYSIS; CASE CONTROL STUDY; DRUG UTILIZATION; MEDICATION THERAPY MANAGEMENT; ORGANIZATION AND MANAGEMENT; PROGRAM EVALUATION; RETROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA; UNITED STATES; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DRUG PRESCRIPTIONS; DRUG UTILIZATION; FEMALE; HUMANS; MALE; MEDICARE; MEDICATION ADHERENCE; MEDICATION THERAPY MANAGEMENT; PROGRAM EVALUATION; RETROSPECTIVE STUDIES; UNITED STATES;

EID: 84982242233     PISSN: 02782715     EISSN: 15445208     Source Type: Journal    
DOI: 10.1377/hlthaff.2015.1456     Document Type: Article

References (33)

1. Aitken M, Kleinrock M, Lyle J, Caskey L. Medicine use and shifting costs of healthcare: a review of the use of medicines in the United States in 2013 [Internet]. Parsippany (NJ): IMS Institute for Healthcare Informatics; April [cited 2016 Jun 22]. Available from: http:// www.imshealth.com/en/thoughtleadership/ ims-institute/reports/ use-of-medicines-in-the-us-2013
2. World Health Organization. Adherence to long-term therapies: evidence for action [Internet]. Geneva: WHO; 2003 [cited 2016 Jun 22]. Available from: http://apps.who.int/ iris/bitstream/10665/42682/1/ 9241545992.pdf
3. Sokol MC, McGuigan KA, Verbrugge RR, Epstein RS. Impact of medication adherence on hospitalization risk and healthcare cost. Med Care. 2005;43(6):521-30.
4. Ho PM, Magid DJ, Shetterly SM, Olson KL, Maddox TM, Peterson PN, et al. Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease. Am Heart J. 2008;155(4):772-9.
5. Roebuck MC, Liberman JN, Gemmill- Toyama M, Brennan TA. Medication adherence leads to lower health care use and costs despite increased drug spending. Health Aff (Millwood). 2011;30(1):91-9.
6. Holdford DA, Inocencio TJ. Adherence and persistence associated with an appointment-based medication synchronization program. J Am Pharm Assoc (2003). 2013;53(6): 576-83.
7. National Community Pharmacists Association. National Adherence Survey: the promise and prospects of medication synchronization [Internet]. Alexandria (VA): Langer Research Associates; 2014 Aug [cited Jun 22]. Available from: http:// www.ncpa.co/pdf/med-syncnational- adherence-survey.pdf
8. American Pharmacists Association Foundation. Pharmacy's Appointment Based Model (ABM) [Internet]. Washington (DC): APhA Foundation; [cited 2016 Jun 22]. Available from: http://www.apha foundation.org/appointmentbased- model
9. Bonner L. Med sync catching on across nation [Internet]. Washington (DC): American Pharmacists Association; 2015 Jan 8 [cited 2016 Jun 22]. Available from: https:// www.pharmacist.com/med-synccatching- across-nation
10. Holdford D, Saxena K. Impact of appointment-based medication synchronization on existing users of chronic medications. J Manag Care Spec Pharm. 2015;21(8):662-9.
11. Krumme AA, Isaman DL, Stolpe SF, Dougherty S, Choudhry NK. Prevalence, effectiveness, and characteristics of pharmacy-based medication synchronization programs. Am J Manag Care. 2016;22(3):179-86.
12. California Assembly Committee on Health. Bill analysis: health care coverage: prescription drugs: refills [Internet]. Sacramento (CA): The Committee; 2014 Apr 29 [cited 2016 Jun 22]. (California Assembly Bill 2148, proposed). Available from: http://www.leginfo.ca.gov/pub/13- 14/bill/asm/ab_2401-2450/ab_ 2418_cfa_20140428_123836_asm_ comm.html
13. Academy of Managed Care Pharmacy, American Pharmacists Association. Medicare star ratings: stakeholder proceedings on community pharmacy and managed care partnerships in quality. J Am Pharm Assoc (2003). 2014;54(3):228-40.
14. Centers for Medicare and Medicaid Services. Medicare and you: 2015 [Internet]. Baltimore (MD): CMS; Sep [cited 2016 Jun 22]. Available from: https://www .medicare.gov/pubs/ebook/pdf/ Medicare_and_You-2015.pdf
15. Ward BW, Schiller JS, Goodman RA. Multiple chronic conditions among US adults: a 2012 update. Prev Chronic Dis. 2014;11:E62.
16. Centers for Medicare and Medicaid Services. Chronic conditions among Medicare beneficiaries, chartbook, edition [Internet]. Baltimore (MD): CMS; 2012 [cited 2016 Jun 22] Available from: https:// www.cms.gov/Research-Statistics- Data-and-Systems/Statistics-Trendsand- Reports/Chronic-Conditions/ Downloads/2012Chartbook.pdf
17. Iyengar RN, Balagere DS, Henderson RR, LeFrancois AL, Rabbitt RM, Frazee SG. Association between dispensing channel and medication adherence among Medicare beneficiaries taking medications to treat diabetes, high blood pressure, or high blood cholesterol. J Manag Care Spec Pharm. 2014;20(8):851-61.
18. Blum J, Spitalnic P. Announcement of calendar year (CY) 2014 Medicare Advantage capitation rates and Medicare Advantage and Part D payment policies and final call letter [Internet]. Baltimore (MD): Centers for Medicare and Medicaid Services; Apr 2 [cited 2016 Jun 22]. Available from: https://www.cms .gov/medicare/health-plans/ medicareadvtgspecratestats/ downloads/announcement2013.pdf
19. Peterson AM, Nau DP, Cramer JA, Benner J, Gwadry-Sridhar F, Nichol M. A checklist for medication compliance and persistence studies using retrospective databases. Value Health. 2007;10(1):3-12.
20. Centers for Medicare and Medicaid Services. Medicare health and drug plan quality and performance ratings Part C and Part D technical notes [Internet]. Baltimore (MD): CMS; 2012 Aug 9 [cited 2016 Jun 22]. Available from: https:// www.cms.gov/medicare/ prescription-drug-coverage/ prescriptiondrugcovgenin/ downloads/technical-notes- 2013-.pdf
21. KBM Group. AmeriLINK consumer database [Internet]. Richardson (TX): AmeriLINK Consumer Database Group; [cited 2016 Jun 22]. Available from: http:// www.kbmg.com/products/ amerilink/.
22. Duru OK, Schmittdiel JA, Dyer WT, Parker MM, Uratsu CS, Chan J, et al. Mail-order pharmacy use and adherence to diabetes-related medications. Am J Manag Care. 2010;16(1): 33-40.
23. Schmittdiel JA, Karter AJ, Dyer W, Parker M, Uratsu C, Chan J, et al. The comparative effectiveness of mail order pharmacy use vs. local pharmacy use on LDL-C control in new statin users. J Gen Intern Med. 2011;26(12):1396-402.
24. Choudhry NK, Glynn RJ, Avorn J, Lee JL, Brennan TA, Reisman L, et al. Untangling the relationship between medication adherence and post- myocardial infarction outcomes: medication adherence and clinical outcomes. Am Heart J. 2014;167(1): 51-8.e5.
25. Centers for Medicare and Medicaid Services. Medicare Advantage Value- Based Insurance Design Model [Internet]. Baltimore (MD): CMS; 2016 Mar 3 [cited 2016 Jun 22]. Available from: https://innovation.cms.gov/ initiatives/vbid/
26. Lee JL, Maciejewski M, Raju S, Shrank WH, Choudhry NK. Valuebased insurance design: quality improvement but no cost savings. Health Aff (Millwood). 2013;32(7): 1251-7.
27. Freudenheim M. Some employers are offering free drugs. New York Times [serial on the Internet]. 2007 Feb 21 [cited 2016 Jun 22]. Available from: http://www.nytimes.com/ 2007/02/21/business/21free.html? pagewanted=all&_r=0
28. BusinessWire [Internet]. Philadelphia (PA): BusinessWire; 2007. Press release, New Aetna Rx-Savings program cuts cost for medications used to treat chronic health conditions; Dec 5 [cited 2016 Jun 22]. Available from: http:// www.businesswire.com/news/ home/20071205005589/en/Aetna- Rx-Savings-SM-Program-Cuts-Cost- Medications#.VgmpeMtVhBc
29. Fuhrmans V. New tack on copays: cutting them. Wall Street Journal [serial on the Internet]. 2007 May 8 [cited 2016 Jun 22]. Available from: http://www.wsj.com/articles/ SB117857848288195042
30. Choudhry NK, Avorn J, Glynn RJ, Antman EM, Schneeweiss S, Toscano M, et al. Full coverage for preventive medications after myocardial infarction. N Engl J Med. 2011;365(22):2088-97.
31. Hsu J, Price M, Huang J, Brand R, Fung V, Hui R, et al. Unintended consequences of caps on Medicare drug benefits. N Engl J Med. 2006; 354(22):2349-59.
32. Loewenstein G, Brennan T, Volpp KG. Asymmetric paternalism to improve health behaviors. JAMA. 2007;298(20):2415-7.
33. Keller PA, Harlam B, Loewenstein G, Volpp KG. Enhanced active choice: a new method to motivate behavior change. J Consum Psychol. 2011; 21:376-83.