Emergence of the colistin resistance mcr-1 determinant in commensal Escherichia coli from residents of long-term-care facilities in Italy

Journal of Antimicrobial Chemotherapy

Volumn 71, Issue 8, 2016, Pages 2329-2331

  Giufrè, Maria ^a   Monaco, Monica ^a   Accogli, Marisa ^a   Pantosti, Annalisa ^a   Cerquetti, Marina ^a   Farina, Claudio ^b   Fazii, Paolo ^c   Mattei, Romano ^d   Moro, Maria Luisa ^e   Pompa, Maria Grazia ^f   Sarti, Mario ^g  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b PAPA GIOVANNI XXIII HOSPITAL   (Italy)

^c SPIRITO SANTO HOSPITAL   (Italy)

^d CAMPO DI MARTE HOSPITAL   (Italy)

^e Agency for Health and Social Care of Emilia Romagna   (Italy)

^f MINISTRY OF HEALTH   (Italy)

^g S Agostino Estense Hospital   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; GENTAMICIN; IMIPENEM; MEROPENEM; TIGECYCLINE; ANTIINFECTIVE AGENT; ESCHERICHIA COLI PROTEIN; MCR-1 PROTEIN, E COLI;

ANTIBIOTIC RESISTANCE; BACTERIAL GENE; ESCHERICHIA COLI; HEALTH CARE FACILITY; ITALY; LETTER; MCR-1 GENE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; AGED; DRUG EFFECTS; ESCHERICHIA COLI INFECTION; FEMALE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; LONG TERM CARE; MALE; MICROBIOLOGY; SYMBIOSIS; TRANSMISSION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; COLISTIN; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; FEMALE; HUMANS; ITALY; LONG-TERM CARE; MALE; SYMBIOSIS;

EID: 84982206761     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkw195     Document Type: Letter

References (10)

1. Poulsakou G, Bassetti M, Righi E et al. Current and future treatment options for infections caused by multidrug-resistant Gram-negative pathogens. Future Microbiol 2014; 9: 1053-69.
2. Liu YY, Wang Y, Walsh TR et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis 2016; 16: 161-8.
3. Skov R, Monnet D. Plasmid-mediated colistin resistance (mcr-1 gene): three months later, the story unfolds. Euro Surveill 2016; 21: pii=30155.
4. Hasman H, Hammerum AM, Hansen F et al. Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015. Euro Surveill 2015; 20: pii=30085.
5. O'Fallon E, Kandell R, Schreiber R et al. Acquisition of multidrug-resistant Gram-negative bacteria: incidence and risk factors within a long-term care population. Infect Control Hosp Epidemiol 2010; 31: 1148-53.
6. Giufrè M, Graziani C, Accogli M et al. Escherichia coli of human and avian origin: detection of clonal groups associated with fluoroquinolone and multidrug resistance in Italy. J Antimicrob Chemother 2012; 67: 860-7.
7. Stoesser N, Mathers AJ, Moore CE et al. Colistin resistance gene mcr-1 and pHNSHP45 plasmid in human isolates of Escherichia coli and Klebsiella pneumoniae. Lancet Infect Dis 2016; 16: 285-6.
8. Arcilla MS, van Hattem JM, Matamoros S et al. Dissemination of the mcr-1 colistin resistance gene. Lancet Infect Dis 2016; 16: 147-9.
9. Hu Y, Liu F, Lin IY et al. Dissemination of the mcr-1 colistin resistance gene. Lancet Infect Dis 2016; 16: 146-7.
10. Lim CJ, Cheng AC, Kennon J et al. Prevalence of multidrug-resistant organisms and risk factors for carriage in long-term care facilities: a nested case-control study. J Antimicrob Chemother 2014; 69: 1972-80.