A ketogenic diet increases transport and oxidation of ketone bodies in RG2 and 9L gliomas without affecting tumor growth

Neuro-Oncology

Volumn 18, Issue 8, 2016, Pages 1079-1087

  De Feyter, Henk M ^a   Behar, Kevin L ^a   Rao, Jyotsna U ^a   Madden Hennessey, Kirby ^a   Ip, Kevan L ^a   Hyder, Fahmeed ^c   Drewes, Lester R ^b   Geschwind, Jean François ^a   De Graaf, Robin A ^a,c   Rothman, Douglas L ^a,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA DULUTH   (United States)

^c Yale University   (United States)

Author keywords

13C MRS; Glioma; Ketogenic diet; MCT1; Metabolism

Indexed keywords

KETONE BODY; MONOCARBOXYLATE TRANSPORTER; 3 HYDROXYBUTYRIC ACID; COTRANSPORTER; MONOCARBOXYLATE TRANSPORT PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN CORTEX; BRAIN METABOLISM; CANCER GROWTH; CANCER SURVIVAL; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; GLIOMA; KETOGENIC DIET; MALE; NONHUMAN; OXIDATION KINETICS; RAT; SURVIVAL RATE; TRANSPORT KINETICS; TUMOR VOLUME; UPREGULATION; ANIMAL; BRAIN TUMOR; DIET THERAPY; DISEASE MODEL; FISCHER 344 RAT; METABOLISM; SURVIVAL ANALYSIS; TUMOR CELL LINE;

3-HYDROXYBUTYRIC ACID; ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; DIET, KETOGENIC; DISEASE MODELS, ANIMAL; GLIOMA; KETONE BODIES; MALE; MONOCARBOXYLIC ACID TRANSPORTERS; RATS, INBRED F344; SURVIVAL ANALYSIS; SYMPORTERS; TUMOR BURDEN;

EID: 84982078847     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/now088     Document Type: Article

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