Study protocol: First nationwide comparative audit of acute lower gastrointestinal bleeding in the UK

BMJ Open

Volumn 6, Issue 8, 2016, Pages

  Oakland, Kathryn ^a   Guy, Richard ^b   Uberoi, Raman ^b   Seeney, Frances ^a   Collins, Gary ^c   Grant Casey, John ^a   Mortensen, Neil ^b   Murphy, Mike ^a   Jairath, Vipul ^d,e  

^a NHS BLOOD AND TRANSPLANT   (United Kingdom)

^b OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT;

ACUTE DISEASE; ARTICLE; BLOOD TRANSFUSION; CHARLSON COMORBIDITY INDEX; COMORBIDITY; GASTROINTESTINAL ENDOSCOPY; GASTROINTESTINAL HEMORRHAGE; HOSPITAL READMISSION; HUMAN; INTERVENTIONAL RADIOLOGY; LENGTH OF STAY; MEDICAL AUDIT; MORTALITY; NORTHERN IRELAND; PRACTICE GUIDELINE; PROSPECTIVE STUDY; SCOTLAND; WALES; ADOLESCENT; ADULT; AGED; CLINICAL AUDIT; CLINICAL TRIAL; EPIDEMIOLOGY; FEMALE; MALE; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; QUESTIONNAIRE; UNITED KINGDOM; YOUNG ADULT;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; CLINICAL AUDIT; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; LENGTH OF STAY; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RESEARCH DESIGN; SURVEYS AND QUESTIONNAIRES; UNITED KINGDOM; YOUNG ADULT;

EID: 84981745037     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2016-011752     Document Type: Article

References (36)

1. Williams JG, Roberts SE, Ali MF, et al. Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: A review of the evidence. Gut 2007;56(Suppl 1):1-113.
2. Hreinsson JP, Gumundsson S, Kalaitzakis E, et al. Lower gastrointestinal bleeding: incidence, etiology and outcomes in a population-based setting. Eur J Gast Hepatol 2013;25:37-43.
3. Lanas A, Garcia-Rodríguez LA, Polo-Tomás M, et al. The changing face of hospitalisation due to gastrointestinal bleeding and perforation. Aliment Pharmacol Ther 2011;33:585-91.
4. Strate LL, Ayanian JZ, Kotler G, et al. Risk factors for mortality in lower intestinal bleeding. Clin Gastroenterol Hepatol 2008;6:1004-10.
5. Nagata N, Niikura R, Aoki T, et al. Colonic diverticular hemorrhage associated with the use of nonsteroidal anti-inflammatory drugs, low-dose aspirin, antiplatelet drugs, and dual therapy. J Gastroenterol Hepatol 2014;29:1786-93.
6. Lanas A, García-Rodríguez LA, Polo-Tomás M, et al. Time trends and impact of upper and lower gastrointestinal bleeding and perforation in clinical practice. Am J Gastroenterol 2009;104:1633-41.
7. Tinegate H, Chattree S, Iqbal A, et al. Northern Regional Transfusion Committee. Ten-year pattern of red blood cell use in the North of England. Transfusion 2013;53:483-9.
8. Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013;368:11-21.
9. National Institute for Clinical Excellence (NICE) Clinical Guideline 141. Acute upper gastrointestinal bleeding in over 16s: management. 2012. http://www. nice. org
10. Scottish Intercollegiate Guidelines Network (SIGN). Management of acute upper and lower gastrointestinal bleeding, Guideline no. 105, 2008. http://www. sign. Ac. uk
11. Gralnek IM, Dumonceau JM, Kuipers EJ, et al. Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2015;47:a1-46.
12. Barkun AN, Bardou M, Kuipers EJ, et al. International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2010;152:101.
13. Green BT, Rockey DC, Portwood G, et al. Urgent colonoscopy for evaluation and management of acute lower gastrointestinal hemorrhage: A randomized controlled trial. Am J Gastroenterol 2005;100:2395-402.
14. Laine L, Shah A. Randomized trial of urgent vs. elective colonoscopy in patients hospitalized with lower GI bleeding. Am J Gastroenterol 2010;105:2636-41.
15. Tan KK, Strong DH, Shore T, et al. The safety and efficacy of mesenteric embolization in the management of acute lower gastrointestinal haemorrhage. Ann Coloproctol 2013;29:205-8.
16. Adusumilli S, Gosselink MP, Ctercteko G, et al. The efficacy of selective arterial embolization in the management of colonic bleeding. Tech Coloproctol 2014;18:529-33.
17. National Confidential Enquiry into Patient Outcome and Death (NCEPOD). Time to get control? A review of the care received by patients who had a severe gastrointestinal haemorrhage. 2015. http://www. ncepod. org. uk
18. Centre for Workforce Intelligence. Securing the future workforce supply: clinical radiology stocktake. 2012. http://www. cfwi. org. uk
19. Hunt BJ, Allard S, Keeling D, et al. The British Committee for Standards in Haematology. A practical guideline for the haematological management of major haemorrhage. Br J Haematol 2015;170:788-803.
20. Harris A, Atterbury C, Chaffe B, et al. on behalf of British Committee for Standards in Haematology. Guideline on the administration of blood components. http://www. bcshguidelines. com
21. Hearnshaw SA, Logan RF, Lowe D, et al. Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in 2007 UK audit. Gut 2011;60:1327-35.
22. The Royal College of Radiologists and the British Society of Interventional Radiology. Provision of interventional radiology services. 2014, ISBN: 978-1-905034-64-2 Ref No. BFCR(14)12.
23. National Confidential Enquiry into Patient Outcome and Death (NCEPOD). An Age Old Problem: A review of the care received by elderly patients undergoing surgery, 2012. http://www. ncepod. org. uk
24. National Emergency Laparotomy Audit (NELA) Project Team. First patient report of The National Emergency Laparotomy Audit. London: Royal College of Anaeathestists, 2015. http://www. nela. org. uk
25. National Patient Safety Agency. The transfusion of blood and blood components in an emergency. Rapid Response Report, 2010.
26. Murphy MF, Wallington TB, Kelsey P, et al. British Committee for Standards in Haematology, Blood Transfusion Task Force. Guidelines for the clinical use of red cell transfusions. Br J Haematol 2001;113:24-31.
27. Makris M, Van Veen JJ, Tait CR, et al. British Committee for Standards in Haematology. Guideline on the management of bleeding in patients on antithrombotic agents. Br J Haematol 2013;160:35-46.
28. National Institute for Clinical Excellence (NICE) Guideline NG24. Blood Transfusion. 2015. http://www. nice. org
29. Association of Surgeons of Great Britain and Ireland (ASGBI). Issues in Professional Practice: Emergency General Surgery, 2012. http://www. Asgbi. org. uk
30. World Health Organization. International Statistical Classification of Diseases and Related Health Problems version 10. www. who. int/ classifications/icd/en/
31. Siddique J, Ruhnke GW, Flores A, et al. Applying classification trees to hospital administrative data to identify patients with lower gastrointestinal bleeding. PLoS ONE 2015;10:e0138987.
32. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol 1992;45:613-19.
33. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-83.
34. The Criteria Committee of the New York Heart Association. Nomenclature and criteria for diagnosis of diseases of the heart and great vessels. 9th edn. Boston: Little, Brown & Co, 1994:253-6.
35. The Renal Association: Chronic Kidney Disease Stages. http://www. renal. org
36. Health Research Authority (HRA) Determining whether your study is research. http://www. hra. nhs. uk