A randomized double-blind placebo-controlled trial of lactobacillus reuteri for chronic functional abdominal pain in children

Iranian Journal of Pediatrics

Volumn 25, Issue 6, 2015, Pages

  Eftekhari, Kambiz ^a   Vahedi, Zahra ^b   Aghdam, Mojtaba Kamali ^b   Diaz, Diana Noemi ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ZANJAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Children; Functional abdominal pain; Lactobacillus reuteri

Indexed keywords

BIOGAIA; PLACEBO; PROBIOTIC AGENT; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ABSENCE OF SIDE EFFECTS; ADOLESCENT; AGE; ARTICLE; BODY WEIGHT; CHILD; CHRONIC FUNCTIONAL ABDOMINAL PAIN; CONTROLLED STUDY; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; HUMAN; LACTOBACILLUS REUTERI; MAJOR CLINICAL STUDY; PAIN FREQUENCY; PAIN INTENSITY; PAIN LOCATION; PAIN MEASUREMENT; PAIN PARAMETERS; PAIN SEVERITY; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; TREATMENT OUTCOME;

EID: 84981743106     PISSN: 20082142     EISSN: 20082150     Source Type: Journal    
DOI: 10.5812/ijp.2616     Document Type: Article

References (20)

1. Sreedharan R, Chris A. Functional abdominal pain (non organic chronic abdominal pain). In: Stanton K, Geme S, Behrman S, editors. Nelson Text Book of Pediatrics. Elsevier; 2011. pp. 1643-6.
2. Helgeland H, Flagstad G, Grøtta J, Vandvik P, Kristensen H, Markestad T. Diagnosing Pediatric Functional Abdominal Pain in Children (4-15 Years Old) According to the Rome III Criteria: Results From a Norwegian Prospective Study. J Pediatr Gastroenterol Nutr. 2009;49(3):309-15. doi:10.1097/MPG.0b013e31818de3ab. [PubMed: 19525874]
3. Perquin CW, Hunfeld JA, Hazebroek-Kampschreur AA, Suijlekom-Smit LW, Passchier J, Koes BW, et al. The natural course of chronic benign pain in childhood and adolescence: a two-year population-based follow-up study. Eur J Pain. 2003;7(6):551-9. doi:10.1016/s1090-3801(03)00060-0. [PubMed: 14575668]
4. Achenbach TM, McConaughy SH, Howell CT. Child/adolescent behavioral and emotional problems: implications of cross-informant correlations for situational specificity. Psychol Bull. 1987;101(2):213-32. [PubMed: 3562706]
5. Farahmand F, Modaresi V, Najafi M, Khodadad A, Moetamed F, Modarres Z. Prevalence of celiac disease in Iranian children with recurrent abdominal pain referred to a pediatric referral center. Iran J Pediatr. 2011;21(1):33-8. [PubMed: 23056761]
6. Jee SR, Jung HK, Min BH, Choi KD, Rhee PL, Kang YW, et al. [Guidelines for the treatment of functional dyspepsia]. Korean J Gastroenterol. 2011;57(2):67-81. [PubMed: 21350319]
7. Korterink JJ, Ockeloen L, Benninga MA, Tabbers MM, Hilbink M, Deckers-Kocken JM. Probiotics for childhood functional gastrointestinal disorders: a systematic review and meta-analysis. Acta Paediatr. 2014;103(4):365-72. doi:10.1111/apa.12513. [PubMed: 24236577]
8. Szajewska H. Prebiotics, synbiotics and fermented products. In: Kleinman RE, Sanderson IR, Goulet O, editors. Walker’s Pediatric Gastrointestinal Disease. 5th ed ed. Decker: Hamilton; 2008. pp. 399-409.
9. Jafari E, Vahedi H, Merat S, Momtahen S, Riahi A. Therapeutic effects, tolerability and safety of a multi-strain probiotic in Iranian adults with irritable bowel syndrome and bloating. Arch Iran Med. 2014;17(7):466-70. [PubMed: 24979556]
10. Horvath A, Szajewska H. Probiotics, prebiotics, and dietary fiber in the management of functional gastrointestinal disorders. World Rev Nutr Diet. 2013;108:40-8. doi:10.1159/000351483. [PubMed: 24029785]
11. Demers M, Dagnault A, Desjardins J. A randomized double-blind controlled trial: Impact of probiotics on diarrhea in patients treated with pelvic radiation. Clin Nutr. 2014;33(5):761-7. doi:10.1016/j.clnu.2013.10.015. [PubMed: 24200199]
12. Horvath A, Dziechciarz P, Szajewska H. Meta-analysis: Lactobacillus rhamnosus GG for abdominal pain-related functional gastrointestinal disorders in childhood. Aliment Pharmacol Ther. 2011;33(12):1302-10. doi:10.1111/j.1365-2036.2011.04665.x. [PubMed:21507030]
13. Bieri D, Reeve RA, Champion DG, Addicoat L, Ziegler JB. The faces pain scale for the self-assessment of the severity of pain experienced by children: Development, initial validation, and preliminary investigation for ratio scale properties. Pain. 1990;41(2):139-50. doi:10.1016/0304-3959(90)90018-9. [PubMed: 2367140]
14. Saps M, Lu P, Bonilla S. Cow’s-milk allergy is a risk factor for the development of FGIDs in children. J Pediatr Gastroenterol Nutr. 2011;52(2):166-9. doi:10.1097/MPG.0b013e3181e85b55. [PubMed: 20975580]
15. Marshall JK, Thabane M, Garg AX, Clark WF, Moayyedi P, Collins SM, et al. Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery. Gut. 2010;59(5):605-11. doi:10.1136/gut.2009.202234. [PubMed: 20427395]
16. Wilhelm SM, Brubaker CM, Varcak EA, Kale-Pradhan PB. Effectiveness of probiotics in the treatment of irritable bowel syndrome. Pharmacotherapy. 2008;28(4):496-505. doi:10.1592/phco.28.4.496. [PubMed: 18363533]
17. Niv E, Naftali T, Hallak R, Vaisman N. The efficacy of Lactobacillus reuteri ATCC 55730 in the treatment of patients with irritable bowel syndrome--a double blind, placebo-controlled, randomized study. Clin Nutr. 2005;24(6):925-31. doi:10.1016/j.clnu.2005.06.001. [PubMed: 16051399]
18. Romano C, Ferrau V, Cavataio F, Iacono G, Spina M, Lionetti E, et al. Lactobacillus reuteriin children with functional abdominal pain (FAP). J Paediatr Child Health. 2014;50(10):E68-71. doi:10.1111/j.1440-1754.2010.01797.x. [PubMed: 20626584]
19. Gawronska A, Dziechciarz P, Horvath A, Szajewska H. A randomized double-blind placebo-controlled trial of Lactobacillus GG for abdominal pain disorders in children. Aliment Pharmacol Ther. 2007;25(2):177-84. doi:10.1111/j.1365-2036.2006.03175.x. [PubMed: 17229242]
20. Design of Treatment Trials C, Irvine EJ, Whitehead WE, Chey WD, Matsueda K, Shaw M, et al. Design of treatment trials for functional gastrointestinal disorders. Gastroenterology. 2006;130(5):1538-51. doi:10.1053/j.gastro.2005.11.058. [PubMed: 16678567]