An efficient PEGylated liposomal nanocarrier containing cell-penetrating peptide and pH-sensitive hydrazone bond for enhancing tumor-targeted drug delivery

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 6199-6214

  Ding, Yuan ^a   Sun, Dan ^a   Wang, Gui Ling ^a   Yang, Hong Ge ^a   Xu, Hai Feng ^a   Chen, Jian Hua ^b   Xie, Ying ^a,c   Wang, Zhi Qiang ^d  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b JIANGHAN UNIVERSITY   (China)

^c PEKING UNIVERSITY   (China)

^d KENT STATE UNIVERSITY   (United States)

Author keywords

Long circulation; Lysosome escape; Nanocarrier; PH sensitive liposomes; Pharmacokinetics

Indexed keywords

CELL PENETRATING PEPTIDE; DOXORUBICIN; HYDRAZONE DERIVATIVE; LIPOSOME; MACROGOL; STEARIC ACID; ANTINEOPLASTIC ANTIBIOTIC; DRUG CARRIER; MACROGOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CHEMICAL BOND; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL DELIVERY; MALE; NANOPHARMACEUTICS; NONHUMAN; RAT; SURFACE PROPERTY; TUMOR CELL; ANIMAL; BAGG ALBINO MOUSE; BREAST NEOPLASMS; CHEMISTRY; FEMALE; FLOW CYTOMETRY; MOUSE; NUDE MOUSE; PATHOLOGY; PH; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION; TUMOR CELL CULTURE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BREAST NEOPLASMS; CELL-PENETRATING PEPTIDES; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; FLOW CYTOMETRY; HUMANS; HYDRAZONES; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 84981736395     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S92519     Document Type: Article

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