Environment, Genetic and Epigenetic Alterations and Pediatric Central Nervous System Tumors

Encyclopedia of Environmental Health

Volumn , Issue , 2011, Pages 559-568

  Kunkle, B ^a   Sandberg, D ^b   Jayakar, P ^c   Felty, Q ^a   Roy, D ^a  

^a FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Miami Childrens Hospital   (United States)

Author keywords

Epigenetics; Gene environment interactions; Individual susceptibility; Pediatric central nervous system tumors (pCNSTs)

Indexed keywords

EID: 84981547845     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-444-52272-6.00071-4     Document Type: Chapter

References (18)

1. Biegel J.A. Cytogenetics and molecular genetics of childhood brain tumors. Neuro-Oncology 1999, 1(2):139-151.
2. Bigner S.H., McLendon R.E., Fuchs H., McKeever P.E., Friedman H.S. Chromosomal characteristics of childhood brain tumors. Cancer Genetics and Cytogenetics 1997, 97(2):125-134.
3. Cadieux B., Ching T.T., VandenBerg S.R., Costello J.F. Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Research 2006, 66(17):8469-8476.
4. Gonzalez-Gomez P., Bello M.J., Lomas J., et al. Epigenetic changes in pilocytic astrocytomas and medulloblastomas. International Journal of Molecular Medicine 2003, 11(5):655-660.
5. Kiebish M.A., Seyfried T.N. Absence of pathogenic mitochondrial DNA mutations in mouse brain tumors. BMC Cancer 2005, 5:102.
6. Kleihues P., Louis D.N., Scheithauer B.W., et al. The WHO classification of tumors of the nervous system. Journal of Neuropathology and Experimental Neurology 2002, 61(3):215-225.
7. Kleihues P., Ohgaki H. Phenotype vs. genotype in the evolution of astrocytic brain tumors. Toxicologic Pathology 2000, 28(1):164-170.
8. Lang F.F., Miller D.C., Koslow M., Newcomb E.W. Pathways leading to glioblastoma multiforms: A molecular analysis of genetic alterations in 65 astrocytic tumors. Journal of Neurosurgery 1994, 81(3):427-436.
9. Neumann E., Kalousek D.K., Norman M.G., Steinbok P., Cochrane D.D., Goddard K. Cytogenetic analysis of 109 pediatric central nervous system tumors. Cancer Genetics and Cytogenetics 1993, 71(1):40-49.
10. Park J.R., Eggert A., Caron H. Neuroblastoma: Biology, prognosis, and treatment. Pediatric Clinics of North America 2008, 55(1):97-120.
11. Pietsch T., Taylor M.D., Rutka J.T. Molecular pathogenesis of childhood brain tumors. Journal of Neurooncology 2004, 70(2):203-215.
12. Roberts P., Chumas P.D., Picton S., Bridges L., Livingstone J.H., Sheridan E. A review of the cytogenetics of 58 pediatric brain tumors. Cancer Genetics and Cytogenetics 2001, 131(1):1-12.
13. Roy D., Cai Q., Felty Q., Narayan S. Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers. Journal of Toxicology and Environmental Health Part B: Critical Reviews 2007, 10(4):235-257.
14. Searles N.S., Mueller B.A., De Roos A.J., Viernes H.M., Farin F.M., Checkoway H. Risk of brain tumors in children and susceptibility to organophosphorus insecticides: The potential role of paraoxonase (PON1). Environmental Health Perspectives 2005, 113(7):909-913.
15. Sharma M.K., Zehnbauer B.A., Watson M.A., Gutmann D.H. RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma. Neurology 2005, 65(8):1335-1336.
16. Slikker W., Mei N., Chen T. N-ethyl-N-nitrosourea (ENU) increased brain mutations in prenatal and neonatal mice but not in the adults. Toxicological Sciences 2004, 81(1):112-120.
17. Weiss W.A., Godfrey T., Francisco C., Bishop J.M. Genome-wide screen for allelic imbalance in a mouse model for neuroblastoma. Cancer Research 2000, 60(9):2483-2487.
18. Wiencke J.K., Zheng S., Jelluma N., et al. Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma. Neuro-Oncology 2007, 9(3):271-279.