Alphavirus Restriction by IFITM Proteins

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Volumn 17, Issue 9, 2016, Pages 997-1013

  Weston, Stuart ^a   Czieso, Stephanie ^a   White, Ian J ^a   Smith, Sarah E ^b   Wash, Rachael S ^b   Diaz Soria, Carmen ^b   Kellam, Paul ^a,b   Marsh, Mark ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

alphavirus; IFITM; interferon inducible transmembrane protein; restriction factor; Semliki Forest virus; SFV; virus entry; virus host interaction

Indexed keywords

ANTIVIRUS AGENT; CD63 ANTIGEN; EARLY ENDOSOME ANTIGEN 1; INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ALPHAVIRUS INFECTION; ANTIVIRAL ACTIVITY; ARTICLE; CELL MEMBRANE; CELL SURFACE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOL; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; SEMLIKI FOREST VIRUS; SINDBIS VIRUS; VIRUS ATTACHMENT; VIRUS CAPSID; VIRUS ENTRY; VIRUS PARTICLE;

EID: 84981271783     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12416     Document Type: Article

References (33)

1. Feeley EM, Sims JS, John SP, Chin CR, Pertel T, Chen L-M, Gaiha GD, Ryan BJ, Donis RO, Elledge SJ, Brass AL. IFITM3 inhibits influenza A virus infection by preventing cytosolic entry. PLoS Pathog 2011;7:e1002337.
2. Amini-Bavil-Olyaee S, Choi YJ, Lee JH, Shi M, Huang I, Farzan M. The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry. Cell Host Microbe 2013;13:452–464.
3. Li K, Markosyan RM, Zheng Y-M, Golfetto O, Bungart B, Li M, Ding S, He Y, Liang C, Lee JC, Gratton E, Cohen FS, Liu S-L. IFITM proteins restrict viral membrane hemifusion. PLoS Pathog 2013;9:e1003124.
4. Desai TM, Marin M, Chin CR, Savidis G, Brass AL, Melikyan GB. IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion. PLoS Pathog 2014;10:e1004048.
5. Compton AA, Bruel T, Porrot F, Mallet A, Sachse M, Euvrard M, Liang C, Casartelli N, Schwartz O. IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread. Cell Host Microbe 2014;16:736–747.
6. Tartour K, Appourchaux R, Gaillard J, Nguyen X-N, Durand S, Turpin J, Beaumont E, Roch E, Berger G, Mahieux R, Brand D, Roingeard P, Cimarelli A. IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity. Retrovirology 2014;11:103.
7. Yu J, Li M, Wilkins J, Liang C, Chen BK, Liu S, Yu J, Li M, Wilkins J, Ding S, Swartz TH, Esposito AM, Zheng Y. IFITM proteins restrict HIV-1 infection by antagonizing the envelope glycoprotein. Cell Rep 2015;13:145–156.
8. Helenius A, Kartenbeck J, Simons K, Fries E. On the entry of Semliki forest virus into BHK-21 cells. J Cell Biol 1980;84:404–420.
9. Marsh M, Helenius A. Adsorptive endocytosis of Semliki Forest virus. J Mol Biol 1980;142:439–454.
10. White J, Helenius A. pH-dependent fusion between the Semliki Forest virus membrane and liposomes. Proc Natl Acad Sci USA 1980;77:3273–3277.
11. Marsh M, Bolzau E, Helenius A. Penetration of Semliki Forest virus from acidic prelysosomal vacuoles. Cell 1983;32:931–940.
12. Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, Bieniasz P, Rice CM. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 2011;472:481–485.
13. Bailey CC, Zhong G, Huang I-C, Farzan M. IFITM-family proteins: the cell's first line of antiviral defense. Annu Rev Virol 2014;1:261–283.
14. Diamond MS, Farzan M. The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat Rev Immunol 2013;13:46–57.
15. Brass AL, Huang I-C, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ. The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell 2009;139:1243–1254.
16. Jiang D, Weidner JM, Qing M, Pan X-B, Guo H, Xu C, Zhang X, Birk A, Chang J, Shi P-Y, Block TM, Guo J-T. Identification of five interferon-induced cellular proteins that inhibit west Nile virus and dengue virus infections. J Virol 2010;84:8332–8341.
17. Chan YK, Huang I-C, Farzan M. IFITM proteins restrict antibody-dependent enhancement of dengue virus infection. PLoS One 2012;7:e34508.
18. John SP, Chin CR, Perreira J, Feeley EM, Aker A, Savidis G, Smith SE, Elia AEH, Everitt AR, Vora M, Pertel T, Elledge SJ, Kellam P, Brass AL. The CD225 domain of IFITM3 is required for both IFITM Protein association and inhibition of influenza A virus and dengue virus replication. J Virol 2013;87:7837–7852.
19. Smith SE, Gibson MS, Wash RS, Ferrara F, Wright E, Temperton N, Kellam P, Fife M. Chicken IFITM3 restricts Influenza viruses and Lyssaviruses in vitro. J Virol 2013;87:12957–12966.
20. Weston S, Czieso S, White IJ, Smith SE, Kellam P, Marsh M. A membrane topology model for human interferon inducible transmembrane protein 1. PLoS One 2014;9:e104341.
21. Jia R, Xu F, Qian J, Yao Y, Miao C, Zheng Y-M, Liu S-L, Guo F, Geng Y, Qiao W, Liang C. Identification of an endocytic signal essential for the antiviral action of IFITM3. Cell Microbiol 2014;16:1080–1093.
22. Smith SE, Weston S, Kellam P, Marsh M. IFITM proteins - cellular inhibitors of viral entry. Curr Opin Virol 2014;4:71–77.
23. Perreira JM, Chin CR, Feeley EM, Brass AL. IFITMs restrict the replication of multiple pathogenic viruses. J Mol Biol 2013;425:4937–4955.
24. Kielian M, Chanel-Vos C, Liao M. Alphavirus entry and membrane fusion. Viruses 2010;2:796–825.
25. Schmid S, Fuchs R, Kielian M, Helenius A, Mellman I. Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants. J Cell Biol 1989;108:1291–1300.
26. Marsh M, Wellsteed J, Kern H, Harms E, Helenius A. Monensin inhibits Semliki Forest virus penetration into culture cells. Proc Natl Acad Sci USA 1982;79:5297–5301.
27. Helenius A, Kielian M, Wellsteed J, Mellman I, Rudnick G. Effects of monovalent cations on Semliki Forest virus entry into BHK-21 cells. J Biol Chem 1985;260:5691–5697.
28. Bailey CC, Kondur HR, Huang I-C, Farzan M. Interferon-induced transmembrane protein 3 is a Type II transmembrane protein. J Biol Chem 2013;288:32184–32193.
29. Ling S, Zhang C, Wang W, Cai X, Yu L, Wu F, Zhang L, Tian C. Combined approaches of EPR and NMR illustrate only one transmembrane helix in the human IFITM3. Sci Rep 2016;6:24029.
30. Jia R, Pan Q, Ding S, Rong L, Liu S-L, Geng Y, Qiao W, Liang C. The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization. J Virol 2012;86:13697–13707.
31. Marsh M, Bron R. SFV infection in CHO cells: cell-type specific restrictions to productive virus entry at the cell surface. J Cell Sci 1997;110:95–103.
32. Fraile-Ramos A, Kledal TN, Pelchen-Matthews A, Bowers K, Schwartz TW, Marsh M. The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling. Mol Biol Cell 2001;12:1737–1749.
33. Slot JW, Geuze HJ, Gigengack S, Lienhard GE, James DE. Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat. J Cell Biol 1991;113:123–135.