Therapeutic effects and related mechanisms of erythropoietin sustained-release gelatin hydrogel microspheres on a murine model of hindlimb ischemia

Chinese Journal of Cardiology

Volumn 44, Issue 6, 2016, Pages 524-529

  Xiao, Jinwen ^a   Li, Longhu ^a   Hong, Bingzhe ^a   Xiao, Jianqi ^a   Wei, Dongmei ^a   Jin, Zhe ^a  

^a DALIAN UNIVERSITY   (China)

Author keywords

Erythropoietin; Ischemia; Lower extremity

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD31 ANTIGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; GELATIN; GELATINASE A; MICROSPHERE; PROTEIN KINASE B; SODIUM CHLORIDE; DELAYED RELEASE FORMULATION; HYDROGEL; MMP2 PROTEIN, MOUSE; NOS3 PROTEIN, MOUSE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLE; ARTERY LIGATION; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMORAL ARTERY; HYDROGEL; IMMUNOHISTOCHEMISTRY; LEG ISCHEMIA; LIMB ISCHEMIA; MALE; MOUSE; NONHUMAN; SUSTAINED DRUG RELEASE; THERAPY EFFECT; ANIMAL; C57BL MOUSE; CHEMISTRY; DELAYED RELEASE FORMULATION; DISEASE MODEL; DRUG EFFECTS; HINDLIMB; ISCHEMIA; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; DELAYED-ACTION PREPARATIONS; DISEASE MODELS, ANIMAL; ERYTHROPOIETIN; FEMORAL ARTERY; GELATIN; HINDLIMB; HYDROGELS; ISCHEMIA; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED C57BL; MICROSPHERES; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84980009916     PISSN: 02533758     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0253-3758.2016.06.013     Document Type: Article

References (12)

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