메뉴 건너뛰기




Volumn 68, Issue 3, 2016, Pages 252-260

Statins in Familial Hypercholesterolemia: Consequences for Coronary Artery Disease and All-Cause Mortality

Author keywords

intensity; inverse probability of treatment weighting; lipid lowering

Indexed keywords

ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTITHROMBOCYTIC AGENT; ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN;

EID: 84979895500     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2016.04.054     Document Type: Article
Times cited : (149)

References (27)
  • 1
    • 84924366648 scopus 로고    scopus 로고
    • Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome
    • 1 Sjouke, B., Kusters, D.M., Kindt, I., et al. Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome. Eur Hear J 36 (2014), 560–565.
    • (2014) Eur Hear J , vol.36 , pp. 560-565
    • Sjouke, B.1    Kusters, D.M.2    Kindt, I.3
  • 3
    • 84966551189 scopus 로고    scopus 로고
    • Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217
    • 3 Benn, M., Watts, G.F., Tybjærg-Hansen, A., Nordestgaard, B.G., Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217. Eur Heart J 37 (2016), 1384–1394.
    • (2016) Eur Heart J , vol.37 , pp. 1384-1394
    • Benn, M.1    Watts, G.F.2    Tybjærg-Hansen, A.3    Nordestgaard, B.G.4
  • 4
    • 84864602990 scopus 로고    scopus 로고
    • Cardiovascular risk in relation to functionality of sequence variants in the gene coding for the low-density lipoprotein receptor: a study among 29,365 individuals tested for 64 specific low-density lipoprotein-receptor sequence variants
    • 4 Huijgen, R., Kindt, I., Defesche, J.C., Kastelein, J.J.P., Cardiovascular risk in relation to functionality of sequence variants in the gene coding for the low-density lipoprotein receptor: a study among 29,365 individuals tested for 64 specific low-density lipoprotein-receptor sequence variants. Eur Heart J 33 (2012), 2325–2330.
    • (2012) Eur Heart J , vol.33 , pp. 2325-2330
    • Huijgen, R.1    Kindt, I.2    Defesche, J.C.3    Kastelein, J.J.P.4
  • 5
    • 0035941786 scopus 로고    scopus 로고
    • Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolaemia (ASAP): a prospective, randomised, double-blind trial
    • 5 Smilde, T.J., van Wissen, S., Wollersheim, H., et al. Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolaemia (ASAP): a prospective, randomised, double-blind trial. Lancet 357 (2001), 577–581.
    • (2001) Lancet , vol.357 , pp. 577-581
    • Smilde, T.J.1    van Wissen, S.2    Wollersheim, H.3
  • 6
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • 6 Baigent, C., Keech, A., Kearney, P.M., et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 366 (2005), 1267–1278.
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 7
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
    • 7 Baigent, C., Blackwell, L., Emberson, J., et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 376 (2010), 1670–1681.
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3
  • 8
    • 72449195846 scopus 로고    scopus 로고
    • New opportunities for drug outcomes research in cancer patients: the linkage of the Eindhoven Cancer Registry and the PHARMO Record Linkage System
    • 8 van Herk-Sukel, M.P.P., van de Poll-Franse, L.V., Lemmens, V.E.P.P., et al. New opportunities for drug outcomes research in cancer patients: the linkage of the Eindhoven Cancer Registry and the PHARMO Record Linkage System. Eur J Cancer 46 (2010), 395–404.
    • (2010) Eur J Cancer , vol.46 , pp. 395-404
    • van Herk-Sukel, M.P.P.1    van de Poll-Franse, L.V.2    Lemmens, V.E.P.P.3
  • 9
    • 84979930532 scopus 로고    scopus 로고
    • RIVM. Classification of Medical Interventions version 2.6. 2005. Available at: Accessed June 30
    • 9 RIVM. Classification of Medical Interventions version 2.6. 2005. Available at: http://class.who-fic.nl/browser.aspx?scheme=CMSV-nl.cla. Accessed June 30, 2015.
    • (2015)
  • 10
    • 0003439151 scopus 로고
    • International Statistical Classification of Diseases and Related Health Problems 10th Revision
    • World Health Organization Geneva, Switzerland Available at: Accessed September 18, 2015
    • 10 World Health Organization. International Statistical Classification of Diseases and Related Health Problems 10th Revision. 1978, World Health Organization, Geneva, Switzerland Available at: http://apps.who.int/classifications/icd10/browse/2016/en Accessed September 18, 2015.
    • (1978)
  • 11
    • 2442628111 scopus 로고    scopus 로고
    • Adjusted survival curves with inverse probability weights
    • 11 Cole, S.R., Hernán, M.A., Adjusted survival curves with inverse probability weights. Comput. Methods Programs Biomed 75 (2004), 45–49.
    • (2004) Comput. Methods Programs Biomed , vol.75 , pp. 45-49
    • Cole, S.R.1    Hernán, M.A.2
  • 12
    • 77149125892 scopus 로고    scopus 로고
    • Use of stabilized inverse propensity scores as weights to directly estimate relative risk and its confidence intervals
    • 12 Xu, S., Ross, C., Raebel, M., Shetterly, S., Blanchette, C., Smith, D., Use of stabilized inverse propensity scores as weights to directly estimate relative risk and its confidence intervals. Value Health 13 (2010), 273–277.
    • (2010) Value Health , vol.13 , pp. 273-277
    • Xu, S.1    Ross, C.2    Raebel, M.3    Shetterly, S.4    Blanchette, C.5    Smith, D.6
  • 13
    • 0035102570 scopus 로고    scopus 로고
    • Akaike's information criterion in generalized estimating equations
    • 13 Pan, W., Akaike's information criterion in generalized estimating equations. Biometrics 57 (2001), 120–125.
    • (2001) Biometrics , vol.57 , pp. 120-125
    • Pan, W.1
  • 14
    • 84868944008 scopus 로고    scopus 로고
    • The “Hmisc” Package
    • version 3.14-4. 2014. Available at: Accessed July 23
    • 14 Harrel FE. The “Hmisc” Package, version 3.14-4. 2014. Available at: http://cran.r-project.org/web/packages/Hmisc/Hmisc.pdf. Accessed July 23, 2014.
    • (2014)
    • Harrel, F.E.1
  • 15
    • 84902576469 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • 15 Stone, N.J., Robinson, J., Lichtenstein, A.H., et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 63 (2014), 2889–2934.
    • (2014) J Am Coll Cardiol , vol.63 , pp. 2889-2934
    • Stone, N.J.1    Robinson, J.2    Lichtenstein, A.H.3
  • 16
    • 79959332777 scopus 로고    scopus 로고
    • Efficacy of statins in familial hypercholesterolaemia: a long term cohort study
    • 16 Versmissen, J., Oosterveer, D.M., Yazdanpanah, M., et al. Efficacy of statins in familial hypercholesterolaemia: a long term cohort study. BMJ, 337, 2008, a2423.
    • (2008) BMJ , vol.337 , pp. a2423
    • Versmissen, J.1    Oosterveer, D.M.2    Yazdanpanah, M.3
  • 17
    • 0028181730 scopus 로고
    • By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease?
    • 17 Law, M.R., Wald, N.J., Thompson, S.G., By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease?. BMJ 308 (1994), 367–372.
    • (1994) BMJ , vol.308 , pp. 367-372
    • Law, M.R.1    Wald, N.J.2    Thompson, S.G.3
  • 18
    • 4544275379 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • 18 Grundy, S.M., Cleeman, J.I., Merz, C.N.B., et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. J Am Coll Cardiol 44 (2004), 720–732.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 720-732
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.B.3
  • 19
    • 84893873856 scopus 로고    scopus 로고
    • Severe heterozygous familial hypercholesterolemia and risk for cardiovascular disease: a study of a cohort of 14, 000 mutation carriers
    • 19 Besseling, J., Kindt, I., Hof, M., Kastelein, J.J.P., Hutten, B.A., Hovingh, G.K., Severe heterozygous familial hypercholesterolemia and risk for cardiovascular disease: a study of a cohort of 14, 000 mutation carriers. Atherosclerosis 233 (2014), 219–223.
    • (2014) Atherosclerosis , vol.233 , pp. 219-223
    • Besseling, J.1    Kindt, I.2    Hof, M.3    Kastelein, J.J.P.4    Hutten, B.A.5    Hovingh, G.K.6
  • 20
    • 84868628467 scopus 로고    scopus 로고
    • Familial hypercholesterolemia in the Danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication
    • 20 Benn, M., Watts, G.F., Tybjaerg-Hansen, A., Nordestgaard, B.G., Familial hypercholesterolemia in the Danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication. J Clin Endocrinol Metab 97 (2012), 3956–3964.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 3956-3964
    • Benn, M.1    Watts, G.F.2    Tybjaerg-Hansen, A.3    Nordestgaard, B.G.4
  • 21
    • 84979907658 scopus 로고    scopus 로고
    • Cascade screening for familial hypercholesterolemia: prevention of coronary artery disease in a large cohort of FH heterozygotes
    • In: Huijen R, editor. Familial Hypercholesterolemia: The Dutch Approach. Amsterdam, the Netherlands: 2012:288–304. Available at: Accessed August 20
    • 21 Huijgen R, Versmissen J, Oosterveer DM, et al. Cascade screening for familial hypercholesterolemia: prevention of coronary artery disease in a large cohort of FH heterozygotes. In: Huijen R, editor. Familial Hypercholesterolemia: The Dutch Approach. Amsterdam, the Netherlands: 2012:288–304. Available at: http://dare.uva.nl/document/2/114977. Accessed August 20, 2015.
    • (2015)
    • Huijgen, R.1    Versmissen, J.2    Oosterveer, D.M.3
  • 22
    • 84890461947 scopus 로고    scopus 로고
    • Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease
    • a
    • 22 Nordestgaard, B.G., Chapman, M.J., Humphries, S.E., et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease. Eur Heart J 34 (2013), 3478–3490 a.
    • (2013) Eur Heart J , vol.34 , pp. 3478-3490
    • Nordestgaard, B.G.1    Chapman, M.J.2    Humphries, S.E.3
  • 23
    • 77049105368 scopus 로고    scopus 로고
    • Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in the Netherlands
    • 23 Pijlman, A., Huijgen, R., Verhagen, S.N., et al. Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in the Netherlands. Atherosclerosis 209 (2010), 189–194.
    • (2010) Atherosclerosis , vol.209 , pp. 189-194
    • Pijlman, A.1    Huijgen, R.2    Verhagen, S.N.3
  • 24
    • 0036607353 scopus 로고    scopus 로고
    • Cost effectiveness analysis of different approaches of screening for familial hypercholesterolaemia
    • 24 Marks, D., Wonderling, D., Thorogood, M., et al. Cost effectiveness analysis of different approaches of screening for familial hypercholesterolaemia. BMJ, 324, 2002, 1303.
    • (2002) BMJ , vol.324 , pp. 1303
    • Marks, D.1    Wonderling, D.2    Thorogood, M.3
  • 25
    • 79959347897 scopus 로고    scopus 로고
    • Probabilistic cost-effectiveness analysis of cascade screening for familial hypercholesterolaemia using alternative diagnostic and identification strategies
    • 25 Nherera, L., Marks, D., Minhas, R., et al. Probabilistic cost-effectiveness analysis of cascade screening for familial hypercholesterolaemia using alternative diagnostic and identification strategies. Heart 97 (2011), 1175–1181.
    • (2011) Heart , vol.97 , pp. 1175-1181
    • Nherera, L.1    Marks, D.2    Minhas, R.3
  • 26
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • 26 Ridker, P.M., Danielson, E., Fonseca, F.A.H., et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 359 (2008), 2195–2207.
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.H.3
  • 27
    • 84931411520 scopus 로고    scopus 로고
    • Ezetimibe added to statin therapy after acute coronary syndromes
    • 27 Cannon, C.P., Blazing, M., Giugliano, R.P., et al. Ezetimibe added to statin therapy after acute coronary syndromes. N Engl J Med 372 (2015), 2387–2397.
    • (2015) N Engl J Med , vol.372 , pp. 2387-2397
    • Cannon, C.P.1    Blazing, M.2    Giugliano, R.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.