Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma

Cancer discovery

Volumn 5, Issue 7, 2015, Pages 723-729

  Jafri, Mariam ^a   Wake, Naomi C ^a   Ascher, David B ^b   Pires, Douglas E V ^b   Gentle, Dean ^b   Morris, Mark R ^a   Rattenberry, Eleanor ^a   Simpson, Michael A ^b   Trembath, Richard C ^b   Weber, Astrid ^a   Woodward, Emma R ^a   Donaldson, Alan ^b   Blundell, Tom L ^a   Latif, Farida ^a   Maher, Eamonn R ^b  

^a GUY S HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CDK4 PROTEIN, HUMAN; CDK6 PROTEIN, HUMAN; CDKN2B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 2B;

CHEMICAL STRUCTURE; CHEMISTRY; DNA SEQUENCE; FEMALE; GENETIC PREDISPOSITION; GENETICS; GERMLINE MUTATION; HUMAN; KIDNEY CARCINOMA; KIDNEY TUMOR; MALE; METABOLISM; MIDDLE AGED; MISSENSE MUTATION; PEDIGREE; PROCEDURES;

CARCINOMA, RENAL CELL; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P15; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; MODELS, MOLECULAR; MUTATION, MISSENSE; PEDIGREE; SEQUENCE ANALYSIS, DNA;

EID: 84979835557     PISSN: None     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-14-1096     Document Type: Article

References (0)