Recovery from pneumonia requires efferocytosis which is impaired in smokers and those with low body mass index and enhanced by statins

Thorax

Volumn 71, Issue 11, 2016, Pages 1052-1054

  Wootton, Daniel G ^a,b   Diggle, Peter J ^c   Court, Joanne ^d   Eneje, Odiri ^d   Keogan, Lynne ^b   Macfarlane, Laura ^d   Wilks, Sarah ^d   Woodhead, Mark ^e,f   Gordon, Stephen B ^c  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^c LANCASTER UNIVERSITY   (United Kingdom)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^e MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Macrophage Biology; Neutrophil Biology; Pneumonia; Tobacco and the lung

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ARTICLE; BODY MASS; BRONCHOSCOPY; COHORT ANALYSIS; COMMUNITY ACQUIRED PNEUMONIA; COMORBIDITY; CONTROLLED STUDY; EFFEROCYTOSIS; FLOW CYTOMETRY; HUMAN; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MAJOR CLINICAL STUDY; PHAGOCYTOSIS; PRIORITY JOURNAL; SMOKING; ADULT; AGED; APOPTOSIS; COMMUNITY ACQUIRED INFECTION; ENGLAND; MIDDLE AGED; NEUTROPHIL; PHYSIOLOGY; PNEUMONIA;

ADULT; AGED; APOPTOSIS; BODY MASS INDEX; BRONCHOALVEOLAR LAVAGE; BRONCHOSCOPY; COMMUNITY-ACQUIRED INFECTIONS; COMORBIDITY; ENGLAND; FLOW CYTOMETRY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MACROPHAGES, ALVEOLAR; MIDDLE AGED; NEUTROPHILS; PHAGOCYTOSIS; PNEUMONIA; SMOKING;

EID: 84979652116     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2016-208505     Document Type: Article

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