Brief Report: Changes in Antiphospholipid Antibody Titers During Pregnancy: Effects on Pregnancy Outcomes

Arthritis and Rheumatology

Volumn 68, Issue 8, 2016, Pages 1964-1969

  Yelnik, Cecile M ^a   Porter, T Flint ^b   Branch, D Ware ^b   Laskin, Carl A ^c   Merrill, Joan T ^d   Guerra, Marta M ^e   Lockshin, Michael D ^e   Buyon, Jill P ^f   Petri, Michelle ^g   Sammaritano, Lisa R ^e   Stephenson, Mary D ^h   Kim, Mimi Y ⁱ   Salmon, Jane E ^e  

^a UNIV LILLE   (France)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^e HOSPITAL FOR SPECIAL SURGERY   (United States)

^f NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF ILLINOIS   (United States)

ⁱ ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; HEPARIN; HYDROXYCHLOROQUINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G PHOSPHOLIPID; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M PHOSPHOLIPID; LUPUS ANTICOAGULANT; PHOSPHOLIPID; PHOSPHOLIPID ANTIBODY; PREDNISONE; UNCLASSIFIED DRUG;

ADULT; ADVERSE OUTCOME; ANTIBODY TITER; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CORTICOSTEROID THERAPY; FEMALE; FETUS DEATH; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTRAUTERINE GROWTH RETARDATION; MAJOR CLINICAL STUDY; NEWBORN DEATH; PLACENTA INSUFFICIENCY; PREECLAMPSIA; PREGNANCY; PREGNANCY OUTCOME; PREMATURE LABOR; PRIORITY JOURNAL; PUERPERIUM; SECOND TRIMESTER PREGNANCY; SYSTEMIC LUPUS ERYTHEMATOSUS; THIRD TRIMESTER PREGNANCY;

EID: 84979516620     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39668     Document Type: Article

References (16)

1. De Jesus GR, Agmon-Levin N, Andrade CA, Andreoli L, Chighizola CB, Porter TF, et al. 14th International Congress on Antiphospholipid Antibodies Task Force report on obstetric antiphospholipid syndrome. Autoimmun Rev 2014;13:795–813.
2. Viall CA, Chamley LW. Histopathology in the placentae of women with antiphospholipid antibodies: a systematic review of the literature. Autoimmun Rev 2015;14:446–71.
3. Mekinian A, Loire-Berson P, Nicaise-Roland P, Lachassinne E, Stirnemann J, Boffa MC, et al. Outcomes and treatment of obstetric antiphospholipid syndrome in women with low antiphospholipid antibody levels. J Reprod Immunol 2012;94:222–6.
4. Lockshin MD, Kim M, Laskin CA, Guerra M, Branch DW, Merrill J, et al. Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies. Arthritis Rheum 2012;64:2311–8.
5. Buyon JP, Kim MY, Guerra MM, Laskin CA, Petri M, Lockshin MD, et al. Predictors of pregnancy outcomes in patients with lupus: a cohort study. Ann Intern Med 2015;163:153–63.
6. Wilson WA, Gharavi AE, Koike T, Lockshin MD, Branch DW, Piette JC, et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthritis Rheum 1999;42:1309–11.
7. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295–306.
8. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
9. Sanchez-Guerrero J, Alarcon-Segovia D. Course of antiphospholipid antibodies in patients with primary antiphospholipid syndrome before, during and after pregnancy treated with low dose aspirin: relationship of antibody levels to outcome in 7 patients. J Rheumatol 1992;19:1083–8.
10. Topping J, Quenby S, Farquharson R, Malia R, Greaves M. Marked variation in antiphospholipid antibodies during pregnancy: relationships to pregnancy outcome. Hum Reprod 1999;14:224–8.
11. Salazar-Páramo M, Jara LJ, Ramos A, Barile L, Machado G, García-De La Torre I. Longitudinal study of antinuclear and anticardiolipin antibodies in pregnant women with systemic lupus erythematosus and antiphospholipid syndrome. Rheumatol Int 2002;22:142–7.
12. Lynch AM, Rutledge JH, Stephens JK, Murphy JR, Marlar RA, Davila GH, et al. Longitudinal measurement of anticardiolipin antibodies during normal pregnancy: a prospective study. Lupus 1995;4:365–9.
13. Donohoe S, Quenby S, Mackie I, Panal G, Farquharson R, Malia R, et al. Fluctuations in levels of antiphospholipid antibodies and increased coagulation activation markers in normal and heparin-treated antiphospholipid syndrome pregnancies. Lupus 2002;11:11–20.
14. Kwak JY, Barini R, Gilman-Sachs A, Beaman KD, Beer AE. Down-regulation of maternal antiphospholipid antibodies during early pregnancy and pregnancy outcome. Am J Obstet Gynecol 1994;171:239–46.
15. Holers VM, Girardi G, Mo L, Guthridge JM, Molina H, Pierangeli SS, et al. Complement C3 activation is required for antiphospholipid antibody-induced fetal loss. J Exp Med 2002;195:211–20.
16. Out HJ, de Groot PG, Hasselaar P, dan Vliet M, Derksen RH. Fluctuations of anticardiolipin antibody levels in patients with systemic lupus erythematosus: a prospective study. Ann Rheum Dis 1989;48:1023–8.